YCBF_ECOLI
ID YCBF_ECOLI Reviewed; 236 AA.
AC P40876; P75861;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 27-APR-2001, sequence version 3.
DT 03-AUG-2022, entry version 147.
DE RecName: Full=Uncharacterized fimbrial chaperone YcbF;
DE Flags: Precursor;
GN Name=ycbF; OrderedLocusNames=b0944, JW5124;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 165-236.
RX PubMed=2992959; DOI=10.1111/j.1432-1033.1985.tb09068.x;
RA Larsen N.J., Jensen K.F.;
RT "Nucleotide sequence of the pyrD gene of Escherichia coli and
RT characterization of the flavoprotein dihydroorotate dehydrogenase.";
RL Eur. J. Biochem. 151:59-65(1985).
RN [5]
RP IDENTIFICATION.
RX PubMed=7984428; DOI=10.1093/nar/22.22.4756;
RA Borodovsky M., Rudd K.E., Koonin E.V.;
RT "Intrinsic and extrinsic approaches for detecting genes in a bacterial
RT genome.";
RL Nucleic Acids Res. 22:4756-4767(1994).
RN [6]
RP FUNCTION, AND INDUCTION.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=20345943; DOI=10.1111/j.1462-2920.2010.02202.x;
RA Korea C.G., Badouraly R., Prevost M.C., Ghigo J.M., Beloin C.;
RT "Escherichia coli K-12 possesses multiple cryptic but functional chaperone-
RT usher fimbriae with distinct surface specificities.";
RL Environ. Microbiol. 12:1957-1977(2010).
CC -!- FUNCTION: Part of the elfADCG-ycbUVF fimbrial operon, which promotes
CC adhesion of bacteria to different abiotic surfaces. Could be required
CC for the biogenesis of fimbriae. {ECO:0000269|PubMed:20345943}.
CC -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250}.
CC -!- INDUCTION: Expression is negatively regulated by H-NS and subjected to
CC cAMP receptor protein (CRP)-mediated catabolite repression.
CC {ECO:0000269|PubMed:20345943}.
CC -!- MISCELLANEOUS: The operon is cryptic under classical laboratory
CC conditions, but is functional when constitutively expressed.
CC {ECO:0000305|PubMed:20345943}.
CC -!- SIMILARITY: Belongs to the periplasmic pilus chaperone family.
CC {ECO:0000305}.
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DR EMBL; U00096; AAC74030.2; -; Genomic_DNA.
DR EMBL; AP009048; BAA35699.2; -; Genomic_DNA.
DR EMBL; X02826; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; G64834; G64834.
DR RefSeq; NP_415464.4; NC_000913.3.
DR RefSeq; WP_001307699.1; NZ_CP047127.1.
DR AlphaFoldDB; P40876; -.
DR SMR; P40876; -.
DR BioGRID; 4259443; 7.
DR STRING; 511145.b0944; -.
DR PaxDb; P40876; -.
DR PRIDE; P40876; -.
DR EnsemblBacteria; AAC74030; AAC74030; b0944.
DR EnsemblBacteria; BAA35699; BAA35699; BAA35699.
DR GeneID; 945559; -.
DR KEGG; ecj:JW5124; -.
DR KEGG; eco:b0944; -.
DR PATRIC; fig|511145.12.peg.978; -.
DR EchoBASE; EB2298; -.
DR eggNOG; COG3121; Bacteria.
DR HOGENOM; CLU_070768_2_2_6; -.
DR OMA; VSWRTIN; -.
DR PhylomeDB; P40876; -.
DR BioCyc; EcoCyc:EG12397-MON; -.
DR PRO; PR:P40876; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0030288; C:outer membrane-bounded periplasmic space; IEA:InterPro.
DR GO; GO:0071555; P:cell wall organization; IEA:InterPro.
DR GO; GO:0061077; P:chaperone-mediated protein folding; IEA:InterPro.
DR Gene3D; 2.60.40.10; -; 2.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR008962; PapD-like_sf.
DR InterPro; IPR036316; Pili_assmbl_chap_C_dom_sf.
DR InterPro; IPR001829; Pili_assmbl_chaperone_bac.
DR InterPro; IPR016148; Pili_assmbl_chaperone_C.
DR InterPro; IPR018046; Pili_assmbl_chaperone_CS.
DR InterPro; IPR016147; Pili_assmbl_chaperone_N.
DR Pfam; PF02753; PapD_C; 1.
DR Pfam; PF00345; PapD_N; 1.
DR PRINTS; PR00969; CHAPERONPILI.
DR SUPFAM; SSF49354; SSF49354; 1.
DR SUPFAM; SSF49584; SSF49584; 1.
DR PROSITE; PS00635; PILI_CHAPERONE; 1.
PE 2: Evidence at transcript level;
KW Chaperone; Fimbrium biogenesis; Immunoglobulin domain; Periplasm;
KW Reference proteome; Signal.
FT SIGNAL 1..26
FT /evidence="ECO:0000255"
FT CHAIN 27..236
FT /note="Uncharacterized fimbrial chaperone YcbF"
FT /id="PRO_0000009291"
SQ SEQUENCE 236 AA; 25853 MW; 19BB101ECDFE5607 CRC64;
MTNTWNRLAL LIFAVLSLLV AGELQAGVVV GGTRFIFPAD RESISILLTN TSQESWLINS
KINRPTRWAG GEASTVPAPL LAAPPLILLK PGTTGTLRLL RTESDILPVD RETLFELSIA
SVPSGKVENQ SVKVAMRSVF KLFWRPEGLP GDPLEAYQQL RWTRNSQGVQ LTNPTPYYIN
LIQVSVNGKA LSNVGVVPPK SQRQTSWCQA IAPCHVAWRA INDYGGLSAK KEQNLP
