YCBU_ECOLI
ID YCBU_ECOLI Reviewed; 180 AA.
AC P75859;
DT 27-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 131.
DE RecName: Full=Uncharacterized fimbrial-like protein YcbU;
DE Flags: Precursor;
GN Name=ycbU; OrderedLocusNames=b0942, JW0925;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP FUNCTION, AND INDUCTION.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=20345943; DOI=10.1111/j.1462-2920.2010.02202.x;
RA Korea C.G., Badouraly R., Prevost M.C., Ghigo J.M., Beloin C.;
RT "Escherichia coli K-12 possesses multiple cryptic but functional chaperone-
RT usher fimbriae with distinct surface specificities.";
RL Environ. Microbiol. 12:1957-1977(2010).
CC -!- FUNCTION: Part of the elfADCG-ycbUVF fimbrial operon, which promotes
CC adhesion of bacteria to different abiotic surfaces.
CC {ECO:0000269|PubMed:20345943}.
CC -!- INDUCTION: Expression is negatively regulated by H-NS and subjected to
CC cAMP receptor protein (CRP)-mediated catabolite repression.
CC {ECO:0000269|PubMed:20345943}.
CC -!- MISCELLANEOUS: The operon is cryptic under classical laboratory
CC conditions, but is functional when constitutively expressed.
CC {ECO:0000305|PubMed:20345943}.
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DR EMBL; U00096; AAC74028.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA35697.1; -; Genomic_DNA.
DR PIR; E64834; E64834.
DR RefSeq; NP_415462.1; NC_000913.3.
DR RefSeq; WP_000730614.1; NZ_STEB01000006.1.
DR AlphaFoldDB; P75859; -.
DR SMR; P75859; -.
DR BioGRID; 4259441; 14.
DR STRING; 511145.b0942; -.
DR PaxDb; P75859; -.
DR PRIDE; P75859; -.
DR EnsemblBacteria; AAC74028; AAC74028; b0942.
DR EnsemblBacteria; BAA35697; BAA35697; BAA35697.
DR GeneID; 66670782; -.
DR GeneID; 945561; -.
DR KEGG; ecj:JW0925; -.
DR KEGG; eco:b0942; -.
DR PATRIC; fig|1411691.4.peg.1332; -.
DR EchoBASE; EB3477; -.
DR eggNOG; COG3539; Bacteria.
DR HOGENOM; CLU_088965_0_1_6; -.
DR InParanoid; P75859; -.
DR OMA; NLEGCPT; -.
DR PhylomeDB; P75859; -.
DR BioCyc; EcoCyc:G6484-MON; -.
DR PRO; PR:P75859; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0009289; C:pilus; IBA:GO_Central.
DR GO; GO:0043709; P:cell adhesion involved in single-species biofilm formation; IMP:EcoCyc.
DR Gene3D; 2.60.40.1090; -; 1.
DR InterPro; IPR000259; Adhesion_dom_fimbrial.
DR InterPro; IPR036937; Adhesion_dom_fimbrial_sf.
DR InterPro; IPR008966; Adhesion_dom_sf.
DR Pfam; PF00419; Fimbrial; 1.
DR SUPFAM; SSF49401; SSF49401; 1.
PE 2: Evidence at transcript level;
KW Reference proteome; Signal.
FT SIGNAL 1..24
FT /evidence="ECO:0000255"
FT CHAIN 25..180
FT /note="Uncharacterized fimbrial-like protein YcbU"
FT /id="PRO_0000013765"
SQ SEQUENCE 180 AA; 18914 MW; C45D8B660ED6E743 CRC64;
MKKKTIFQCV ILFFSILNIH VGMAGPEQVS MHIYGNVVDQ GCDVATKSAL QNIHIGDFNI
SDFQAANTVS TAADLNIDIT GCAAGITGAD VLFSGEADTL APTLLKLTDT GGSGGMATGI
AVQILDAQSQ QEIPLNQVQP LTPLKAGDNT LKYQLRYKST KAGATGGNAT AVLYFDLVYQ
