YCCM_ECOLI
ID YCCM_ECOLI Reviewed; 357 AA.
AC P52636; P75886; Q9R7Q0;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 2.
DT 03-AUG-2022, entry version 146.
DE RecName: Full=Putative electron transport protein YccM;
GN Name=yccM; OrderedLocusNames=b0992, JW0977;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 262-357.
RC STRAIN=K12;
RA Rock C.O., Tsay J.-T., Jackowski S.;
RL Submitted (NOV-1995) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP IDENTIFICATION.
RA Rudd K.E.;
RL Unpublished observations (MAR-1996).
RN [6]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U00096; AAC74077.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA36134.1; -; Genomic_DNA.
DR EMBL; U38541; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; F64840; F64840.
DR RefSeq; NP_415512.1; NC_000913.3.
DR RefSeq; WP_000829662.1; NZ_SSZK01000002.1.
DR AlphaFoldDB; P52636; -.
DR BioGRID; 4262838; 8.
DR STRING; 511145.b0992; -.
DR PaxDb; P52636; -.
DR PRIDE; P52636; -.
DR EnsemblBacteria; AAC74077; AAC74077; b0992.
DR EnsemblBacteria; BAA36134; BAA36134; BAA36134.
DR GeneID; 946295; -.
DR KEGG; ecj:JW0977; -.
DR KEGG; eco:b0992; -.
DR PATRIC; fig|1411691.4.peg.1279; -.
DR EchoBASE; EB3023; -.
DR eggNOG; COG0348; Bacteria.
DR HOGENOM; CLU_033147_0_0_6; -.
DR InParanoid; P52636; -.
DR OMA; NFWCRYL; -.
DR PhylomeDB; P52636; -.
DR BioCyc; EcoCyc:G6513-MON; -.
DR PRO; PR:P52636; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR Pfam; PF12801; Fer4_5; 2.
DR PROSITE; PS00198; 4FE4S_FER_1; 2.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 1: Evidence at protein level;
KW 4Fe-4S; Cell inner membrane; Cell membrane; Electron transport; Iron;
KW Iron-sulfur; Membrane; Metal-binding; Reference proteome; Repeat;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..357
FT /note="Putative electron transport protein YccM"
FT /id="PRO_0000159303"
FT TOPO_DOM 1..36
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 37..54
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 55..91
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 92..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 115..158
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 159..181
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 182..195
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 196..218
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 219..309
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 310..332
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TOPO_DOM 333..357
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 242..270
FT /note="4Fe-4S ferredoxin-type 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00711"
FT DOMAIN 269..299
FT /note="4Fe-4S ferredoxin-type 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00711"
FT BINDING 251
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 254
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 257
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT BINDING 261
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 278
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 281
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 284
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000250"
FT BINDING 288
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000250"
FT CONFLICT 262
FT /note="P -> G (in Ref. 4)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 357 AA; 40097 MW; 074076F1DBBAF727 CRC64;
MAENKRTRWQ RRPGTTGGKL PWNDWRNATT WRKATQLLLL AMNIYIAITF WYWVRYYETA
SSTTFVARPG GIEGWLPIAG LMNLKYSLVT GQLPSVHAAA MLLLVAFIVI SLLLKKAFCS
WLCPVGTLSE LIGDLGNKLF GRQCVLPRWL DIPLRGVKYL LLSFFIYIAL LMPAQAIHYF
MLSPYSVVMD VKMLDFFRHM GTATLISVTV LLIASLFIRH AWCRYLCPYG ALMGVVSLLS
PFKIRRNAES CIDCGKCAKN CPSRIPVDKL IQVRTVECTG CMTCVESCPV ASTLTFSLQK
PAANKKAFAL SGWLMTLLVL GIMFAVIGYA MYAGVWQSPV PEELYRRLIP QAPMIGH
