YCDY_ECOLI
ID YCDY_ECOLI Reviewed; 184 AA.
AC P75915;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Chaperone protein YcdY;
GN Name=ycdY; OrderedLocusNames=b1035, JW1018;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA Horiuchi T.;
RT "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 12.7-28.0 min region on the linkage map.";
RL DNA Res. 3:137-155(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP FUNCTION, INTERACTION WITH YCDX, DISRUPTION PHENOTYPE, AND IDENTIFICATION
RP BY MASS SPECTROMETRY.
RC STRAIN=K12 / BW25113;
RX PubMed=21965574; DOI=10.1128/jb.05927-11;
RA Redelberger D., Seduk F., Genest O., Mejean V., Leimkuhler S.,
RA Iobbi-Nivol C.;
RT "YcdY protein of Escherichia coli, an atypical member of the TorD chaperone
RT family.";
RL J. Bacteriol. 193:6512-6516(2011).
CC -!- FUNCTION: Acts as a chaperone that increases YcdX activity, maybe by
CC facilitating the correct insertion of the zinc ions into the catalytic
CC site of YcdX. Involved in the swarming motility process.
CC {ECO:0000269|PubMed:21965574}.
CC -!- SUBUNIT: Interacts with YcdX. {ECO:0000269|PubMed:21965574}.
CC -!- INTERACTION:
CC P75915; P75914: ycdX; NbExp=2; IntAct=EBI-1121634, EBI-1121626;
CC -!- DISRUPTION PHENOTYPE: Mutants show no swarming ability.
CC {ECO:0000269|PubMed:21965574}.
CC -!- MISCELLANEOUS: Does not bind zinc.
CC -!- SIMILARITY: Belongs to the TorD/DmsD family. {ECO:0000305}.
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DR EMBL; U00096; AAC74119.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA35816.1; -; Genomic_DNA.
DR PIR; H64845; H64845.
DR RefSeq; NP_415553.1; NC_000913.3.
DR RefSeq; WP_001001921.1; NZ_SSZK01000090.1.
DR AlphaFoldDB; P75915; -.
DR SMR; P75915; -.
DR BioGRID; 4260062; 9.
DR DIP; DIP-11519N; -.
DR IntAct; P75915; 7.
DR STRING; 511145.b1035; -.
DR jPOST; P75915; -.
DR PaxDb; P75915; -.
DR PRIDE; P75915; -.
DR EnsemblBacteria; AAC74119; AAC74119; b1035.
DR EnsemblBacteria; BAA35816; BAA35816; BAA35816.
DR GeneID; 945609; -.
DR KEGG; ecj:JW1018; -.
DR KEGG; eco:b1035; -.
DR PATRIC; fig|1411691.4.peg.1236; -.
DR EchoBASE; EB3630; -.
DR eggNOG; COG3381; Bacteria.
DR HOGENOM; CLU_077650_7_2_6; -.
DR InParanoid; P75915; -.
DR OMA; DEYLLPW; -.
DR PhylomeDB; P75915; -.
DR BioCyc; EcoCyc:G6541-MON; -.
DR PRO; PR:P75915; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005829; C:cytosol; IDA:EcoCyc.
DR GO; GO:0071978; P:bacterial-type flagellum-dependent swarming motility; IMP:EcoCyc.
DR GO; GO:0006974; P:cellular response to DNA damage stimulus; IEP:EcoliWiki.
DR InterPro; IPR026269; DmsD-type.
DR InterPro; IPR020945; DMSO/NO3_reduct_chaperone.
DR InterPro; IPR036411; TorD-like_sf.
DR Pfam; PF02613; Nitrate_red_del; 1.
DR PIRSF; PIRSF004690; DmsD; 1.
DR SUPFAM; SSF89155; SSF89155; 1.
PE 1: Evidence at protein level;
KW Chaperone; Reference proteome.
FT CHAIN 1..184
FT /note="Chaperone protein YcdY"
FT /id="PRO_0000211657"
SQ SEQUENCE 184 AA; 20724 MW; 1227878F6A00557E CRC64;
MNEFSILCRV LGSLYYRQPQ DPLLVPLFTL IREGKLAANW PLEQDELLTR LQKSCDMTQV
SADYNALFIG DECAVPPYRS AWVEGATEAE VRAFLSERGM PLADTPADHI GTLLLAASWL
EDQSTEDESE ALETLFSEYL LPWCGAFLGK VEAHATTPFW RTMAPLTRDA ISAMWDELEE
DSEE
