ID   YCEM_SALTY              Reviewed;         307 AA.
AC   P37168;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   23-JAN-2002, sequence version 2.
DT   03-AUG-2022, entry version 116.
DE   RecName: Full=Putative oxidoreductase YceM;
DE            EC=1.-.-.-;
GN   Name=yceM; Synonyms=mviM; OrderedLocusNames=STM1169;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2 / KK1004;
RA   van Slooten J.-C., Okada T., Kutsukake K., Pechere J.-C., Harayama S.;
RL   Submitted (SEP-1993) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=LT2;
RX   PubMed=8200538; DOI=10.1016/0378-1119(94)90603-3;
RA   Kutsukake K., Okada T., Yokoseki T., Iino T.;
RT   "Sequence analysis of the flgA gene and its adjacent region in Salmonella
RT   typhimurium, and identification of another flagellar gene, flgN.";
RL   Gene 143:49-54(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
RN   [4]
RP   PROPOSED FUNCTION IN MOUSE VIRULENCE.
RC   STRAIN=LT2 / SL488;
RX   PubMed=2680969; DOI=10.1128/iai.57.11.3276-3280.1989;
RA   Carsiotis M., Stocker B.A., Weinstein D.L., O'Brien A.D.;
RT   "A Salmonella typhimurium virulence gene linked to flg.";
RL   Infect. Immun. 57:3276-3280(1989).
RN   [5]
RP   SHOWS THAT FLGM IS THE REAL MOUSE VIRULENCE GENE IN THIS REGION.
RC   STRAIN=SL3201;
RX   PubMed=8288531; DOI=10.1128/jb.176.2.368-377.1994;
RA   Schmitt C.K., Darnell S.C., Tesh V.L., Stocker B.A.D., O'Brien A.D.;
RT   "Mutation of flgM attenuates virulence of Salmonella typhimurium, and
RT   mutation of fliA represses the attenuated phenotype.";
RL   J. Bacteriol. 176:368-377(1994).
CC   -!- SIMILARITY: Belongs to the Gfo/Idh/MocA family. {ECO:0000305}.
CC   -!- CAUTION: Was originally (PubMed:2680969) thought to be involved in
CC       mouse virulence. It was later shown that the mutation responsible for
CC       the virulence phenotype maps to nearby genes (PubMed:8288531).
CC       {ECO:0000305|PubMed:2680969, ECO:0000305|PubMed:8288531}.
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DR   EMBL; Z26133; CAA81133.1; -; Genomic_DNA.
DR   EMBL; D25292; BAA04981.1; -; Genomic_DNA.
DR   EMBL; AE006468; AAL20099.1; -; Genomic_DNA.
DR   PIR; S40270; S40270.
DR   RefSeq; NP_460140.1; NC_003197.2.
DR   RefSeq; WP_001259734.1; NC_003197.2.
DR   AlphaFoldDB; P37168; -.
DR   SMR; P37168; -.
DR   STRING; 99287.STM1169; -.
DR   PaxDb; P37168; -.
DR   EnsemblBacteria; AAL20099; AAL20099; STM1169.
DR   GeneID; 1252687; -.
DR   KEGG; stm:STM1169; -.
DR   PATRIC; fig|99287.12.peg.1237; -.
DR   HOGENOM; CLU_023194_23_0_6; -.
DR   PhylomeDB; P37168; -.
DR   BioCyc; SENT99287:STM1169-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0000166; F:nucleotide binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
DR   InterPro; IPR000683; Gfo/Idh/MocA-like_OxRdtase_N.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   Pfam; PF01408; GFO_IDH_MocA; 1.
DR   SUPFAM; SSF51735; SSF51735; 1.
PE   1: Evidence at protein level;
KW   Oxidoreductase; Reference proteome.
FT   CHAIN           1..307
FT                   /note="Putative oxidoreductase YceM"
FT                   /id="PRO_0000096655"
FT   CONFLICT        163
FT                   /note="D -> H (in Ref. 1; CAA81133)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        194
FT                   /note="E -> G (in Ref. 1; CAA81133)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   307 AA;  34009 MW;  7CD105D8DFC8B14F CRC64;
     MRTLRIGIVG LGGIAQKAWL PVLTNTAGWT LQGAWSPSRD KALRICESWR IPYVDSLANL
     ASSCDAVFVH SSTASHYAVV SELLNAGVHV CVDKPLAENL RDAERLVALA AQKKLTLMVG
     FNRRFAPLYR ELKTRLGTAA SLRMDKHRTD SVGPHDLRFT LLDDYLHVVD TALWLAGGEA
     RLASGTLLTS ESGEMCYAEH HFSADKLQIT TSMHRRAGSQ RESVQAVTDG GLYDVTDMRE
     WREERGQGIL IKPIPSWQTT LEQRGFVGCA RHFIDCVQNQ TVPETAGEQA ILAQRVVEAL
     WRDAISE