ID   YCF3_TOBAC              Reviewed;         168 AA.
AC   P12204;
DT   01-OCT-1989, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1989, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=Photosystem I assembly protein Ycf3 {ECO:0000255|HAMAP-Rule:MF_00439};
GN   Name=ycf3 {ECO:0000255|HAMAP-Rule:MF_00439};
OS   Nicotiana tabacum (Common tobacco).
OG   Plastid; Chloroplast.
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; lamiids; Solanales; Solanaceae; Nicotianoideae; Nicotianeae;
OC   Nicotiana.
OX   NCBI_TaxID=4097;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Bright Yellow 4;
RX   PubMed=16453699; DOI=10.1002/j.1460-2075.1986.tb04464.x;
RA   Shinozaki K., Ohme M., Tanaka M., Wakasugi T., Hayashida N.,
RA   Matsubayashi T., Zaita N., Chunwongse J., Obokata J.,
RA   Yamaguchi-Shinozaki K., Ohto C., Torazawa K., Meng B.-Y., Sugita M.,
RA   Deno H., Kamogashira T., Yamada K., Kusuda J., Takaiwa F., Kato A.,
RA   Tohdoh N., Shimada H., Sugiura M.;
RT   "The complete nucleotide sequence of the tobacco chloroplast genome: its
RT   gene organization and expression.";
RL   EMBO J. 5:2043-2049(1986).
RN   [2]
RP   FUNCTION, AND DISRUPTION PHENOTYPE.
RX   PubMed=9314531; DOI=10.1083/jcb.139.1.95;
RA   Ruf S., Koessel H., Bock R.;
RT   "Targeted inactivation of a tobacco intron-containing open reading frame
RT   reveals a novel chloroplast-encoded photosystem I-related gene.";
RL   J. Cell Biol. 139:95-102(1997).
RN   [3]
RP   INTERACTION WITH Y3IP1.
RX   PubMed=20807881; DOI=10.1105/tpc.110.073908;
RA   Albus C.A., Ruf S., Schottler M.A., Lein W., Kehr J., Bock R.;
RT   "Y3IP1, a nucleus-encoded thylakoid protein, cooperates with the plastid-
RT   encoded Ycf3 protein in photosystem I assembly of tobacco and
RT   Arabidopsis.";
RL   Plant Cell 22:2838-2855(2010).
CC   -!- FUNCTION: Essential for the assembly of the photosystem I (PSI)
CC       complex. May act as a chaperone-like factor to guide the assembly of
CC       the PSI subunits. {ECO:0000255|HAMAP-Rule:MF_00439,
CC       ECO:0000269|PubMed:9314531}.
CC   -!- SUBUNIT: Interacts with Y3IP1. {ECO:0000269|PubMed:20807881}.
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast thylakoid membrane
CC       {ECO:0000255|HAMAP-Rule:MF_00439}; Peripheral membrane protein
CC       {ECO:0000255|HAMAP-Rule:MF_00439}.
CC   -!- DISRUPTION PHENOTYPE: Non-photosynthetic phenotype due to the absence
CC       of photosystem I (PSI). Can grow only in vitro on sterile sucrose-
CC       containing medium. Under normal light conditions, mutant plants show
CC       severe pigment deficiency and leaf bleaching due to the accumulation of
CC       photooxidative damage. Under low light conditions, mutant plants show a
CC       light-green phenotype, very slow growth and delayed development.
CC       {ECO:0000269|PubMed:9314531}.
CC   -!- SIMILARITY: Belongs to the Ycf3 family. {ECO:0000255|HAMAP-
CC       Rule:MF_00439}.
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DR   EMBL; Z00044; CAA77415.1; -; Genomic_DNA.
DR   PIR; A05191; A05191.
DR   RefSeq; NP_054498.1; NC_001879.2.
DR   AlphaFoldDB; P12204; -.
DR   SMR; P12204; -.
DR   GeneID; 800437; -.
DR   KEGG; nta:800437; -.
DR   OMA; VYYRDGM; -.
DR   OrthoDB; 1270285at2759; -.
DR   GO; GO:0009535; C:chloroplast thylakoid membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0048564; P:photosystem I assembly; IMP:UniProtKB.
DR   Gene3D; 1.25.40.10; -; 1.
DR   HAMAP; MF_00439; Ycf3; 1.
DR   InterPro; IPR022818; PSI_Ycf3_assembly.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR001440; TPR_1.
DR   InterPro; IPR019734; TPR_repeat.
DR   Pfam; PF00515; TPR_1; 1.
DR   SMART; SM00028; TPR; 3.
DR   SUPFAM; SSF48452; SSF48452; 1.
DR   PROSITE; PS50005; TPR; 3.
DR   PROSITE; PS50293; TPR_REGION; 2.
PE   1: Evidence at protein level;
KW   Chloroplast; Membrane; Photosynthesis; Plastid; Repeat; Thylakoid;
KW   TPR repeat.
FT   CHAIN           1..168
FT                   /note="Photosystem I assembly protein Ycf3"
FT                   /id="PRO_0000217825"
FT   REPEAT          35..68
FT                   /note="TPR 1"
FT   REPEAT          72..105
FT                   /note="TPR 2"
FT   REPEAT          120..153
FT                   /note="TPR 3"
SQ   SEQUENCE   168 AA;  19553 MW;  48A0C4C746C4A170 CRC64;
     MPRSRINGNF IDKTFSIVAN ILLRVIPTTS GEKEAFTYYR DGMSAQSEGN YAEALQNYYE
     AMRLEIDPYD RSYILYNIGL IHTSNGEHTK ALEYYFRALE RNPFLPQAFN NMAVICHYRG
     EQAIQQGDSE IAEAWFDQAA EYWKQAIALT PGNYIEAHNW LKITRRFE