YCF48_THEVB
ID YCF48_THEVB Reviewed; 347 AA.
AC Q8DI95;
DT 13-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 95.
DE RecName: Full=Photosystem II assembly protein Ycf48 {ECO:0000255|HAMAP-Rule:MF_01348, ECO:0000303|PubMed:30061392};
DE Flags: Precursor;
GN Name=ycf48 {ECO:0000255|HAMAP-Rule:MF_01348}; OrderedLocusNames=tll1695;
OS Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1).
OC Bacteria; Cyanobacteria; Pseudanabaenales; Thermosynechococcaceae;
OC Thermosynechococcus.
OX NCBI_TaxID=197221;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-2133 / IAM M-273 / BP-1;
RX PubMed=12240834; DOI=10.1093/dnares/9.4.123;
RA Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S.,
RA Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C.,
RA Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M.,
RA Takeuchi C., Yamada M., Tabata S.;
RT "Complete genome structure of the thermophilic cyanobacterium
RT Thermosynechococcus elongatus BP-1.";
RL DNA Res. 9:123-130(2002).
RN [2] {ECO:0007744|PDB:2XBG, ECO:0007744|PDB:5OJ5, ECO:0007744|PDB:5OJP, ECO:0007744|PDB:5OJR}
RP X-RAY CRYSTALLOGRAPHY (1.08 ANGSTROMS) WILD-TYPE AND MUTATED IN COMPLEX
RP WITH D1 C-TERMINAL PEPTIDES, PROBABLE FUNCTION, INTERACTION WITH PSBA,
RP DOMAIN, AND MUTAGENESIS OF 202-ARG--ARG-226.
RC STRAIN=NIES-2133 / IAM M-273 / BP-1;
RX PubMed=30061392; DOI=10.1073/pnas.1800609115;
RA Yu J., Knoppova J., Michoux F., Bialek W., Cota E., Shukla M.K.,
RA Straskova A., Pascual Aznar G., Sobotka R., Komenda J., Murray J.W.,
RA Nixon P.J.;
RT "Ycf48 involved in the biogenesis of the oxygen-evolving photosystem II
RT complex is a seven-bladed beta-propeller protein.";
RL Proc. Natl. Acad. Sci. U.S.A. 115:E7824-E7833(2018).
CC -!- FUNCTION: A factor required for optimal assembly of photosystem II
CC (PSII), acting in the early stages of PSII assembly. Also plays a role
CC in replacement of photodamaged D1 (psbA). Assists YidC in synthesis of
CC chlorophyll-binding proteins. {ECO:0000255|HAMAP-Rule:MF_01348,
CC ECO:0000305|PubMed:30061392}.
CC -!- SUBUNIT: Interacts with the D1 protein (crystallized with PsbA1 or
CC PsbA3), via the latter's C-terminal prepropeptide, may interact with
CC parts of the mature D1 protein as well. {ECO:0000269|PubMed:30061392}.
CC -!- SUBCELLULAR LOCATION: Cellular thylakoid lumen {ECO:0000255|HAMAP-
CC Rule:MF_01348, ECO:0000305|PubMed:30061392}. Note=Associated with a
CC PSII precusor complex on the lumenal side of the thylakoid membrane.
CC {ECO:0000255|HAMAP-Rule:MF_01348, ECO:0000305|PubMed:30061392}.
CC -!- DOMAIN: A 7-bladed beta-propeller torus, about 54 by 46 Angstroms, with
CC a depth of about 25 Angstroms and a central pore.
CC {ECO:0000269|PubMed:30061392}.
CC -!- SIMILARITY: Belongs to the Ycf48 family. {ECO:0000255|HAMAP-
CC Rule:MF_01348}.
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DR EMBL; BA000039; BAC09247.1; -; Genomic_DNA.
DR RefSeq; NP_682485.1; NC_004113.1.
DR RefSeq; WP_011057532.1; NC_004113.1.
DR PDB; 2XBG; X-ray; 1.50 A; A=38-347.
DR PDB; 5OJ5; X-ray; 1.08 A; A=1-347.
DR PDB; 5OJP; X-ray; 1.86 A; A/B/C=39-347.
DR PDB; 5OJR; X-ray; 1.96 A; A/B/C/D=39-347.
DR PDBsum; 2XBG; -.
DR PDBsum; 5OJ5; -.
DR PDBsum; 5OJP; -.
DR PDBsum; 5OJR; -.
DR AlphaFoldDB; Q8DI95; -.
DR SMR; Q8DI95; -.
DR STRING; 197221.22295420; -.
DR EnsemblBacteria; BAC09247; BAC09247; BAC09247.
DR KEGG; tel:tll1695; -.
DR PATRIC; fig|197221.4.peg.1776; -.
DR eggNOG; COG4447; Bacteria.
DR OMA; EGWIAGQ; -.
DR OrthoDB; 1293876at2; -.
DR Proteomes; UP000000440; Chromosome.
DR Gene3D; 2.130.10.10; -; 2.
DR HAMAP; MF_01348; Ycf48; 1.
DR InterPro; IPR028203; PSII_CF48-like_dom.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR016705; Ycf48/Hcf136.
DR Pfam; PF14870; PSII_BNR; 1.
DR PIRSF; PIRSF017875; PSII_HCF136; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Photosynthesis; Photosystem II; Reference proteome; Signal;
KW Thylakoid.
FT SIGNAL 1..38
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01348"
FT CHAIN 39..347
FT /note="Photosystem II assembly protein Ycf48"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01348"
FT /id="PRO_0000239681"
FT MOTIF 202..226
FT /note="Arg-rich patch"
FT /evidence="ECO:0000269|PubMed:30061392"
FT MUTAGEN 202..226
FT /note="RGSFYSTWEPGQTAWEPHNRTTSRR->EGSFYSTWEPGQTAWEPHNETTSEE
FT : No dramatic change from wild-type in 3D structure,
FT replaces Arg-patch."
FT /evidence="ECO:0000269|PubMed:30061392"
FT STRAND 47..51
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 58..67
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 69..73
FT /evidence="ECO:0007829|PDB:5OJ5"
FT TURN 74..76
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 77..83
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 101..108
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 111..117
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 120..126
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 144..151
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 154..159
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 164..169
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 175..178
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 186..190
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 196..199
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 203..209
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 217..220
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 222..225
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 227..232
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 238..242
FT /evidence="ECO:0007829|PDB:5OJ5"
FT TURN 243..245
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 246..251
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 254..258
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 266..270
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 272..281
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 283..288
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 292..297
FT /evidence="ECO:0007829|PDB:5OJ5"
FT HELIX 306..310
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 311..313
FT /evidence="ECO:0007829|PDB:2XBG"
FT STRAND 317..322
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 325..329
FT /evidence="ECO:0007829|PDB:5OJ5"
FT STRAND 334..338
FT /evidence="ECO:0007829|PDB:5OJ5"
SQ SEQUENCE 347 AA; 38639 MW; 2C7AAB0944AAEC72 CRC64;
MFAKQIDIHW QKMKGIKFLH WLLGTVLLWV SLSTPALAIP ALDYNPWEAI QLPTTATILD
MSFIDRHHGW LVGVNATLME TRDGGQTWEP RTLVLDHSDY RFNSVSFQGN EGWIVGEPPI
MLHTTDGGQS WSQIPLDPKL PGSPRLIKAL GNGSAEMITN VGAIYRTKDS GKNWQALVQE
AIGVMRNLNR SPSGEYVAVS SRGSFYSTWE PGQTAWEPHN RTTSRRLHNM GFTPDGRLWM
IVNGGKIAFS DPDNSENWGE LLSPLRRNSV GFLDLAYRTP NEVWLAGGAG ALLCSQDGGQ
TWQQDVDVKK VPSNFYKILF FSPDQGFILG QKGILLRYVT DLTAAPA
