YCGJ_BACSU
ID YCGJ_BACSU Reviewed; 253 AA.
AC O31474;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 24-MAR-2009, sequence version 2.
DT 03-AUG-2022, entry version 111.
DE RecName: Full=Uncharacterized methyltransferase YcgJ;
DE EC=2.1.1.-;
GN Name=ycgJ; OrderedLocusNames=BSU03160;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [2]
RP X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 26-253 IN COMPLEX WITH
RP S-ADENOSYL-L-METHIONINE.
RC STRAIN=168;
RG New York structural genomix research consortium (NYSGXRC);
RT "The crystal structure of ycgJ protein from Bacillus subtilis at 2.1 A
RT resolution.";
RL Submitted (APR-2006) to the PDB data bank.
CC -!- SIMILARITY: Belongs to the methyltransferase superfamily.
CC {ECO:0000305}.
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DR EMBL; AL009126; CAB12110.2; -; Genomic_DNA.
DR PIR; E69758; E69758.
DR RefSeq; NP_388198.2; NC_000964.3.
DR RefSeq; WP_003246488.1; NZ_JNCM01000030.1.
DR PDB; 1XXL; X-ray; 2.10 A; A/B=27-253.
DR PDB; 2GLU; X-ray; 2.91 A; A/B=27-253.
DR PDBsum; 1XXL; -.
DR PDBsum; 2GLU; -.
DR AlphaFoldDB; O31474; -.
DR SMR; O31474; -.
DR STRING; 224308.BSU03160; -.
DR PaxDb; O31474; -.
DR PRIDE; O31474; -.
DR EnsemblBacteria; CAB12110; CAB12110; BSU_03160.
DR GeneID; 938344; -.
DR KEGG; bsu:BSU03160; -.
DR PATRIC; fig|224308.179.peg.330; -.
DR eggNOG; COG2226; Bacteria.
DR InParanoid; O31474; -.
DR OMA; FDFDWWC; -.
DR PhylomeDB; O31474; -.
DR BioCyc; BSUB:BSU03160-MON; -.
DR EvolutionaryTrace; O31474; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0008168; F:methyltransferase activity; IBA:GO_Central.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.150; -; 1.
DR InterPro; IPR013216; Methyltransf_11.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR Pfam; PF08241; Methyltransf_11; 1.
DR SUPFAM; SSF53335; SSF53335; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Methyltransferase; Reference proteome;
KW S-adenosyl-L-methionine; Transferase.
FT CHAIN 1..253
FT /note="Uncharacterized methyltransferase YcgJ"
FT /id="PRO_0000360862"
FT BINDING 45
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000269|Ref.2"
FT BINDING 66..67
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT BINDING 94..95
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT BINDING 110
FT /ligand="S-adenosyl-L-methionine"
FT /ligand_id="ChEBI:CHEBI:59789"
FT /evidence="ECO:0000269|Ref.2"
FT HELIX 27..33
FT /evidence="ECO:0007829|PDB:1XXL"
FT STRAND 40..45
FT /evidence="ECO:0007829|PDB:1XXL"
FT TURN 47..49
FT /evidence="ECO:0007829|PDB:2GLU"
FT HELIX 50..55
FT /evidence="ECO:0007829|PDB:1XXL"
FT HELIX 56..58
FT /evidence="ECO:0007829|PDB:1XXL"
FT STRAND 59..67
FT /evidence="ECO:0007829|PDB:1XXL"
FT HELIX 69..82
FT /evidence="ECO:0007829|PDB:1XXL"
FT STRAND 86..91
FT /evidence="ECO:0007829|PDB:1XXL"
FT HELIX 94..96
FT /evidence="ECO:0007829|PDB:2GLU"
FT STRAND 104..111
FT /evidence="ECO:0007829|PDB:1XXL"
FT HELIX 113..115
FT /evidence="ECO:0007829|PDB:1XXL"
FT HELIX 119..129
FT /evidence="ECO:0007829|PDB:1XXL"
FT STRAND 130..141
FT /evidence="ECO:0007829|PDB:1XXL"
FT HELIX 147..160
FT /evidence="ECO:0007829|PDB:1XXL"
FT HELIX 170..179
FT /evidence="ECO:0007829|PDB:1XXL"
FT STRAND 182..195
FT /evidence="ECO:0007829|PDB:1XXL"
FT HELIX 196..203
FT /evidence="ECO:0007829|PDB:1XXL"
FT HELIX 207..218
FT /evidence="ECO:0007829|PDB:1XXL"
FT HELIX 222..227
FT /evidence="ECO:0007829|PDB:1XXL"
FT STRAND 238..252
FT /evidence="ECO:0007829|PDB:1XXL"
SQ SEQUENCE 253 AA; 28658 MW; 52F80C8274848C27 CRC64;
MTNETPFSKN AEMYRDEKVF AEGEDLGLMI KTAECRAEHR VLDIGAGAGH TALAFSPYVQ
ECIGVDATKE MVEVASSFAQ EKGVENVRFQ QGTAESLPFP DDSFDIITCR YAAHHFSDVR
KAVREVARVL KQDGRFLLVD HYAPEDPVLD EFVNHLNRLR DPSHVRESSL SEWQAMFSAN
QLAYQDIQKW NLPIQYDSWI KRGGTPADRE KQIITHLNHA SDEARDTFCI TLNQNGQPIS
FCLKAILIQG IKR
