YCGR_CUPTR
ID YCGR_CUPTR Reviewed; 269 AA.
AC B3RD79;
DT 13-JUL-2010, integrated into UniProtKB/Swiss-Prot.
DT 02-SEP-2008, sequence version 1.
DT 03-AUG-2022, entry version 69.
DE RecName: Full=Flagellar brake protein YcgR {ECO:0000255|HAMAP-Rule:MF_01457};
DE AltName: Full=Cyclic di-GMP binding protein YcgR {ECO:0000255|HAMAP-Rule:MF_01457};
GN Name=ycgR {ECO:0000255|HAMAP-Rule:MF_01457}; OrderedLocusNames=RALTA_B2277;
OS Cupriavidus taiwanensis (strain DSM 17343 / BCRC 17206 / CCUG 44338 / CIP
OS 107171 / LMG 19424 / R1) (Ralstonia taiwanensis (strain LMG 19424)).
OC Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC Burkholderiaceae; Cupriavidus.
OX NCBI_TaxID=977880;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 17343 / BCRC 17206 / CCUG 44338 / CIP 107171 / LMG 19424 / R1;
RX PubMed=18490699; DOI=10.1101/gr.076448.108;
RA Amadou C., Pascal G., Mangenot S., Glew M., Bontemps C., Capela D.,
RA Carrere S., Cruveiller S., Dossat C., Lajus A., Marchetti M., Poinsot V.,
RA Rouy Z., Servin B., Saad M., Schenowitz C., Barbe V., Batut J., Medigue C.,
RA Masson-Boivin C.;
RT "Genome sequence of the beta-rhizobium Cupriavidus taiwanensis and
RT comparative genomics of rhizobia.";
RL Genome Res. 18:1472-1483(2008).
CC -!- FUNCTION: Acts as a flagellar brake, regulating swimming and swarming
CC in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)-dependent manner.
CC Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead
CC to decreased motility. {ECO:0000255|HAMAP-Rule:MF_01457}.
CC -!- SUBUNIT: Monomer. Interacts with the flagellar basal bodies.
CC {ECO:0000255|HAMAP-Rule:MF_01457}.
CC -!- SUBCELLULAR LOCATION: Bacterial flagellum basal body
CC {ECO:0000255|HAMAP-Rule:MF_01457}.
CC -!- SIMILARITY: Belongs to the YcgR family. {ECO:0000255|HAMAP-
CC Rule:MF_01457}.
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DR EMBL; CU633750; CAQ72854.1; -; Genomic_DNA.
DR RefSeq; WP_012357066.1; NC_010530.1.
DR AlphaFoldDB; B3RD79; -.
DR SMR; B3RD79; -.
DR STRING; 977880.RALTA_B2277; -.
DR EnsemblBacteria; CAQ72854; CAQ72854; RALTA_B2277.
DR GeneID; 29763785; -.
DR KEGG; cti:RALTA_B2277; -.
DR eggNOG; COG5581; Bacteria.
DR HOGENOM; CLU_086025_0_0_4; -.
DR OMA; REYFRVN; -.
DR OrthoDB; 1084216at2; -.
DR BioCyc; CTAI977880:RALTA_RS26535-MON; -.
DR Proteomes; UP000001692; Chromosome 2.
DR GO; GO:0009425; C:bacterial-type flagellum basal body; IEA:UniProtKB-SubCell.
DR GO; GO:0035438; F:cyclic-di-GMP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0071973; P:bacterial-type flagellum-dependent cell motility; IEA:UniProtKB-UniRule.
DR GO; GO:0071945; P:regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed; IEA:UniProtKB-UniRule.
DR Gene3D; 2.30.110.10; -; 1.
DR HAMAP; MF_01457; YcgR; 1.
DR InterPro; IPR009875; PilZ_domain.
DR InterPro; IPR012349; Split_barrel_FMN-bd.
DR InterPro; IPR023787; T3SS_YcgR.
DR InterPro; IPR009926; T3SS_YcgR_PilZN.
DR Pfam; PF07238; PilZ; 1.
DR Pfam; PF07317; YcgR; 1.
PE 3: Inferred from homology;
KW Bacterial flagellum; c-di-GMP; Nucleotide-binding.
FT CHAIN 1..269
FT /note="Flagellar brake protein YcgR"
FT /id="PRO_0000395270"
FT DOMAIN 149..261
FT /note="PilZ"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_01457"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 269 AA; 30084 MW; 7856217BDF862C19 CRC64;
MLREPMNQHD APGPAETGAD SDAETDAETD AETDAGAADD RYRLSHNSQI GTVLRDLAWQ
KCMLSVRTRT AHQFVTSILH VDPVNRTFVF DWCNAEPERM SLMTSEENAF SGLLRGVPVN
FVVGQPAATR YDDGPAFVAE FPEKLYHFQR RRHFRARTLV TKGYRCEMSL PDKTVLGLDI
ADLSLSGVGL RSRTVTADHL PVGTTVAKCR LDFRELGKLE LDMQVVGHWL VGRDDSAIHH
FGCAFVNPDG RMENFLQRLV FALELAHRG
