ID   YCH4_YEAST              Reviewed;         308 AA.
AC   P25600;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 2.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Putative transposon Ty5-1 protein YCL074W;
GN   Name=TY5A; OrderedLocusNames=YCL074W; ORFNames=YCL74W;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=1574125; DOI=10.1038/357038a0;
RA   Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M.,
RA   Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G.,
RA   Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A.,
RA   Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M., Carcano C.,
RA   Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M.,
RA   Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C.,
RA   Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F.,
RA   Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C.,
RA   Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E.,
RA   Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P.,
RA   Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J.,
RA   Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P.,
RA   Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M.,
RA   Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P.,
RA   Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G.,
RA   Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E.,
RA   Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F.,
RA   Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L.,
RA   Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J.,
RA   Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M.,
RA   Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A.,
RA   Richterich P., Roberts A.B., Rodriguez F., Sanz E.,
RA   Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J.,
RA   Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I.,
RA   Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M.,
RA   Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M.,
RA   Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D.,
RA   Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K.,
RA   Sgouros J.G.;
RT   "The complete DNA sequence of yeast chromosome III.";
RL   Nature 357:38-46(1992).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   SEQUENCE REVISION TO 85; 132 AND 246.
RA   Valles G., Volckaerts G.;
RL   Submitted (JUN-2001) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   IDENTIFICATION AS PART OF TRANSPOSON TY5-1.
RX   PubMed=1324434; DOI=10.1038/358717a0;
RA   Voytas D.F., Boeke J.D.;
RT   "Yeast retrotransposon revealed.";
RL   Nature 358:717-717(1992).
CC   -!- CAUTION: Could be the product of a pseudogene unlikely to encode a
CC       functional protein. This is a truncated part of a POL protein in the
CC       mutated, non-functional YCLWTy5-1 transposon. Because of that it is not
CC       part of the S.cerevisiae S288c complete/reference proteome set.
CC       {ECO:0000305|PubMed:1324434, ECO:0000305|PubMed:24374639}.
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DR   EMBL; X59720; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   PIR; S19406; S19406.
DR   AlphaFoldDB; P25600; -.
DR   DIP; DIP-7287N; -.
DR   SGD; S000000579; YCL074W.
DR   VEuPathDB; FungiDB:YCL074W; -.
DR   InParanoid; P25600; -.
DR   GO; GO:0000943; C:retrotransposon nucleocapsid; ISS:SGD.
DR   GO; GO:0003887; F:DNA-directed DNA polymerase activity; ISS:SGD.
DR   GO; GO:0008233; F:peptidase activity; ISS:SGD.
DR   GO; GO:0004540; F:ribonuclease activity; ISS:SGD.
DR   GO; GO:0003723; F:RNA binding; ISS:SGD.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; ISS:SGD.
DR   GO; GO:0032197; P:transposition, RNA-mediated; ISS:SGD.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR013103; RVT_2.
DR   Pfam; PF07727; RVT_2; 1.
DR   SUPFAM; SSF56672; SSF56672; 1.
PE   5: Uncertain;
KW   Transposable element.
FT   CHAIN           1..308
FT                   /note="Putative transposon Ty5-1 protein YCL074W"
FT                   /id="PRO_0000203503"
SQ   SEQUENCE   308 AA;  34507 MW;  63CB03A9AB42E733 CRC64;
     MDVDTAFLNS TMDEPIYVKQ PPGFVNERNP DYVWELYGGM YGLKQAPLLW NEHINNTLKK
     IGFCRHEGEH GLYFRSTSDG PIYIAVYVDD LLVAAPSPKI YDRVKQELTK LYSMKDLGKV
     DKFLGLNIHQ SSNGDITLSL QDYIAKAASE SEINTFKLTQ TPLCNSKPLF ETTSPHLKDI
     TPYQSIVGQL LFCANTGRPD ISYPVSLLSR FLREPRAIHL ESARRVLRYL YTTRSMCLKY
     RSGSQLALTV YCDASHGAIH DLPHSTGGYV TLLAGAPVTW SSKKLKGVIP VPSTEAEYIT
     ASETVMEI