YCHE_ECOLI
ID YCHE_ECOLI Reviewed; 215 AA.
AC P25743; P76025; Q9R7N0;
DT 01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 2.
DT 03-AUG-2022, entry version 144.
DE RecName: Full=UPF0056 membrane protein YhcE;
GN Name=ychE; OrderedLocusNames=b1242, JW1229;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RX PubMed=2015910; DOI=10.1016/0014-5793(91)80358-a;
RA Kessler D., Leibrecht I., Knappe J.;
RT "Pyruvate-formate-lyase-deactivase and acetyl-CoA reductase activities of
RT Escherichia coli reside on a polymeric protein particle encoded by adhE.";
RL FEBS Lett. 281:59-63(1991).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA Wada C., Yamamoto Y., Horiuchi T.;
RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 28.0-40.1 min region on the linkage map.";
RL DNA Res. 3:363-377(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the UPF0056 (MarC) family. {ECO:0000305}.
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DR EMBL; X59501; CAA42090.1; -; Genomic_DNA.
DR EMBL; U00096; AAC74324.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA36122.2; -; Genomic_DNA.
DR PIR; E64871; E64871.
DR RefSeq; NP_415758.1; NC_000913.3.
DR RefSeq; WP_000616554.1; NZ_SSZK01000031.1.
DR AlphaFoldDB; P25743; -.
DR BioGRID; 4263225; 10.
DR STRING; 511145.b1242; -.
DR TCDB; 2.A.95.1.7; the 6 tms neutral amino acid transporter (naat) family.
DR PaxDb; P25743; -.
DR PRIDE; P25743; -.
DR EnsemblBacteria; AAC74324; AAC74324; b1242.
DR EnsemblBacteria; BAA36122; BAA36122; BAA36122.
DR GeneID; 945836; -.
DR KEGG; ecj:JW1229; -.
DR KEGG; eco:b1242; -.
DR PATRIC; fig|1411691.4.peg.1042; -.
DR EchoBASE; EB1318; -.
DR eggNOG; COG2095; Bacteria.
DR HOGENOM; CLU_079909_2_1_6; -.
DR InParanoid; P25743; -.
DR OMA; LFVIMDP; -.
DR PhylomeDB; P25743; -.
DR BioCyc; EcoCyc:EG11342-MON; -.
DR PRO; PR:P25743; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR InterPro; IPR002771; Multi_antbiot-R_MarC.
DR PANTHER; PTHR33508; PTHR33508; 1.
DR Pfam; PF01914; MarC; 1.
DR TIGRFAMs; TIGR00427; TIGR00427; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..215
FT /note="UPF0056 membrane protein YhcE"
FT /id="PRO_0000156901"
FT TRANSMEM 14..34
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 54..74
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 120..140
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 147..167
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 189..209
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 215 AA; 23521 MW; 82679FE8E7C8B71E CRC64;
MIQTFFDFPV YFKFFIGLFA LVNPVGIIPV FISMTSYQTA AARNKTNLTA NLSVAIILWI
SLFLGDTILQ LFGISIDSFR IAGGILVVTI AMSMISGKLG EDKQNKQEKS ETAVRESIGV
VPLALPLMAG PGAISSTIVW GTRYHSISYL FGFFVAIALF ALCCWGLFRM APWLVRVLRQ
TGINVITRIM GLLLMALGIE FIVTGIKGIF PGLLN
