ID   CAYP2_MACFA             Reviewed;         313 AA.
AC   Q9GKR6;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Calcyphosin-2;
DE   AltName: Full=Calcyphosine-2;
GN   Name=CAPS2; ORFNames=QnpA-21934;
OS   Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC   Cercopithecidae; Cercopithecinae; Macaca.
OX   NCBI_TaxID=9541;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Parietal cortex;
RX   PubMed=11574149; DOI=10.1016/s0378-1119(01)00665-5;
RA   Osada N., Hida M., Kususda J., Tanuma R., Iseki K., Hirata M., Suto Y.,
RA   Hirai M., Terao K., Suzuki Y., Sugano S., Hashimoto K.;
RT   "Assignment of 118 novel cDNAs of cynomolgus monkey brain to human
RT   chromosomes.";
RL   Gene 275:31-37(2001).
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DR   EMBL; AB052179; BAB18985.1; -; mRNA.
DR   AlphaFoldDB; Q9GKR6; -.
DR   SMR; Q9GKR6; -.
DR   STRING; 9541.XP_005571630.1; -.
DR   eggNOG; KOG0032; Eukaryota.
DR   Proteomes; UP000233100; Unplaced.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd00051; EFh; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   Pfam; PF13499; EF-hand_7; 1.
DR   SMART; SM00054; EFh; 2.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50222; EF_HAND_2; 3.
PE   2: Evidence at transcript level;
KW   Calcium; Metal-binding; Reference proteome; Repeat.
FT   CHAIN           1..313
FT                   /note="Calcyphosin-2"
FT                   /id="PRO_0000073541"
FT   DOMAIN          144..179
FT                   /note="EF-hand 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   DOMAIN          180..215
FT                   /note="EF-hand 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   DOMAIN          216..251
FT                   /note="EF-hand 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         193
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         195
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         197
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         199
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   BINDING         204
FT                   /ligand="Ca(2+)"
FT                   /ligand_id="ChEBI:CHEBI:29108"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
SQ   SEQUENCE   313 AA;  36087 MW;  C24B74E997CC4BDE CRC64;
     MSRNGRDACR ELIGFFFTHD QSLTIYEYRQ FGKNRTIVLP FIQKSIYSHQ CGRRKGKQYR
     LGDFYVGATL TFLSSDHASL PESIKENTFL KLRITHIDQI ALDSLKTASM DQEDDIVIQE
     TNDRLVFKAI QDVLKEKLHK RGVRILTGLG KYFQQLDKEG NGLLDKADFK QALKVFHLEV
     SEKDFESAWL ILDDNGNGKV DYGEFKRGII GEMNEYRKSY VRKAFMKLDF NKTGSVPITN
     IRKCYCAKKH SQVISGHSTE EEIKSSFLET LKVACSKSDE VSYGEFEDYY EGLSIEIIDD
     EDFVTILRTP WGI