ID   YCIA_ECOL6              Reviewed;         132 AA.
AC   P0A8Z1; P04379;
DT   20-MAR-1987, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-1987, sequence version 1.
DT   03-AUG-2022, entry version 82.
DE   RecName: Full=Acyl-CoA thioester hydrolase YciA;
DE            EC=3.1.2.-;
GN   Name=yciA; OrderedLocusNames=c1719;
OS   Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=199310;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFT073 / ATCC 700928 / UPEC;
RX   PubMed=12471157; DOI=10.1073/pnas.252529799;
RA   Welch R.A., Burland V., Plunkett G. III, Redford P., Roesch P., Rasko D.,
RA   Buckles E.L., Liou S.-R., Boutin A., Hackett J., Stroud D., Mayhew G.F.,
RA   Rose D.J., Zhou S., Schwartz D.C., Perna N.T., Mobley H.L.T.,
RA   Donnenberg M.S., Blattner F.R.;
RT   "Extensive mosaic structure revealed by the complete genome sequence of
RT   uropathogenic Escherichia coli.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:17020-17024(2002).
CC   -!- FUNCTION: Catalyzes the hydrolysis of the thioester bond in palmitoyl-
CC       CoA and malonyl-CoA. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the acyl coenzyme A hydrolase family.
CC       {ECO:0000305}.
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DR   EMBL; AE014075; AAN80186.1; -; Genomic_DNA.
DR   RefSeq; WP_000108160.1; NC_004431.1.
DR   AlphaFoldDB; P0A8Z1; -.
DR   SMR; P0A8Z1; -.
DR   STRING; 199310.c1719; -.
DR   EnsemblBacteria; AAN80186; AAN80186; c1719.
DR   GeneID; 66674925; -.
DR   KEGG; ecc:c1719; -.
DR   eggNOG; COG1607; Bacteria.
DR   HOGENOM; CLU_050164_2_0_6; -.
DR   OMA; MDEMAFL; -.
DR   BioCyc; ECOL199310:C1719-MON; -.
DR   Proteomes; UP000001410; Chromosome.
DR   GO; GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
DR   InterPro; IPR040170; Cytosol_ACT.
DR   InterPro; IPR033120; HOTDOG_ACOT.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   InterPro; IPR006683; Thioestr_dom.
DR   PANTHER; PTHR11049; PTHR11049; 1.
DR   Pfam; PF03061; 4HBT; 1.
DR   SUPFAM; SSF54637; SSF54637; 1.
DR   PROSITE; PS51770; HOTDOG_ACOT; 1.
PE   3: Inferred from homology;
KW   Hydrolase.
FT   CHAIN           1..132
FT                   /note="Acyl-CoA thioester hydrolase YciA"
FT                   /id="PRO_0000053818"
FT   DOMAIN          8..123
FT                   /note="HotDog ACOT-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01106"
SQ   SEQUENCE   132 AA;  14231 MW;  EF29C49DBB6B50DA CRC64;
     MSTTHNVPQG DLVLRTLAMP ADTNANGDIF GGWLMSQMDI GGAILAKEIA HGRVVTVRVE
     GMTFLRPVAV GDVVCCYARC VQKGTTSVSI NIEVWVKKVA SEPIGQRYKA TEALFKYVAV
     DPEGKPRALP VE