ID   YCIA_SALTY              Reviewed;         133 AA.
AC   P0A1A1; P25944;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Acyl-CoA thioester hydrolase YciA;
DE            EC=3.1.2.-;
GN   Name=yciA; OrderedLocusNames=STM1736;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 121-133.
RX   PubMed=2266561; DOI=10.1016/s0022-2836(99)80009-6;
RA   Hannavy K., Barr G.C., Dorman C.J., Adamson J., Mazengera L.R.,
RA   Gallagher M.P., Evans J.S., Levine B.A., Trayer I.P., Higgins C.F.;
RT   "TonB protein of Salmonella typhimurium. A model for signal transduction
RT   between membranes.";
RL   J. Mol. Biol. 216:897-910(1990).
CC   -!- FUNCTION: Catalyzes the hydrolysis of the thioester bond in palmitoyl-
CC       CoA and malonyl-CoA. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the acyl coenzyme A hydrolase family.
CC       {ECO:0000305}.
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DR   EMBL; AE006468; AAL20654.1; -; Genomic_DNA.
DR   EMBL; X56434; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   RefSeq; NP_460695.1; NC_003197.2.
DR   RefSeq; WP_000210317.1; NC_003197.2.
DR   AlphaFoldDB; P0A1A1; -.
DR   SMR; P0A1A1; -.
DR   STRING; 99287.STM1736; -.
DR   PaxDb; P0A1A1; -.
DR   EnsemblBacteria; AAL20654; AAL20654; STM1736.
DR   GeneID; 1253255; -.
DR   KEGG; stm:STM1736; -.
DR   PATRIC; fig|99287.12.peg.1832; -.
DR   HOGENOM; CLU_050164_2_0_6; -.
DR   OMA; MDEMAFL; -.
DR   PhylomeDB; P0A1A1; -.
DR   BioCyc; SENT99287:STM1736-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0047617; F:acyl-CoA hydrolase activity; IBA:GO_Central.
DR   GO; GO:0036042; F:long-chain fatty acyl-CoA binding; IBA:GO_Central.
DR   GO; GO:0006637; P:acyl-CoA metabolic process; IBA:GO_Central.
DR   GO; GO:0006631; P:fatty acid metabolic process; IBA:GO_Central.
DR   InterPro; IPR040170; Cytosol_ACT.
DR   InterPro; IPR033120; HOTDOG_ACOT.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   InterPro; IPR006683; Thioestr_dom.
DR   PANTHER; PTHR11049; PTHR11049; 1.
DR   Pfam; PF03061; 4HBT; 1.
DR   SUPFAM; SSF54637; SSF54637; 1.
DR   PROSITE; PS51770; HOTDOG_ACOT; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..133
FT                   /note="Acyl-CoA thioester hydrolase YciA"
FT                   /id="PRO_0000053820"
FT   DOMAIN          8..123
FT                   /note="HotDog ACOT-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01106"
FT   CONFLICT        121..122
FT                   /note="DP -> GS (in Ref. 2; X56434)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   133 AA;  14364 MW;  2373900804CF65A5 CRC64;
     MTTMDNTPQG ELVLRTLAMP ADTNANGDIF GGWLMSQMDI GGAILAKEIA HGRVVTVRVE
     GMTFLRPVAV GDVVCCYARC VKRGTTSISI NIEVWVKKVA SEPIGQRYKA TEALFIYVAV
     DPDGKPRPLP VQG