ID   YCIB_BRUMB              Reviewed;         220 AA.
AC   C0RFI0;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 59.
DE   RecName: Full=Inner membrane-spanning protein YciB {ECO:0000255|HAMAP-Rule:MF_00189};
GN   Name=yciB {ECO:0000255|HAMAP-Rule:MF_00189}; OrderedLocusNames=BMEA_A1992;
OS   Brucella melitensis biotype 2 (strain ATCC 23457).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=546272;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 23457;
RA   Setubal J.C., Boyle S., Crasta O.R., Gillespie J.J., Kenyon R.W., Lu J.,
RA   Mane S., Nagrani S., Shallom J.M., Shallom S., Shukla M., Snyder E.E.,
RA   Sobral B.W., Wattam A.R., Will R., Williams K., Yoo H., Munk C., Tapia R.,
RA   Han C., Detter J.C., Bruce D., Brettin T.S.;
RT   "Brucella melitensis ATCC 23457 whole genome shotgun sequencing project.";
RL   Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in cell envelope biogenesis, maintenance of cell
CC       envelope integrity and membrane homeostasis. {ECO:0000255|HAMAP-
CC       Rule:MF_00189}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00189}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00189}.
CC   -!- SIMILARITY: Belongs to the YciB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00189}.
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DR   EMBL; CP001488; ACO01652.1; -; Genomic_DNA.
DR   RefSeq; WP_004686251.1; NC_012441.1.
DR   AlphaFoldDB; C0RFI0; -.
DR   EnsemblBacteria; ACO01652; ACO01652; BMEA_A1992.
DR   KEGG; bmi:BMEA_A1992; -.
DR   HOGENOM; CLU_089554_1_1_5; -.
DR   OMA; AWVNFKL; -.
DR   Proteomes; UP000001748; Chromosome I.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00189; YciB; 1.
DR   InterPro; IPR006008; YciB.
DR   PANTHER; PTHR36917; PTHR36917; 1.
DR   Pfam; PF04279; IspA; 1.
DR   TIGRFAMs; TIGR00997; ispZ; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..220
FT                   /note="Inner membrane-spanning protein YciB"
FT                   /id="PRO_1000124249"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        57..77
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        86..106
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        123..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        156..176
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        187..207
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
SQ   SEQUENCE   220 AA;  24808 MW;  79803BC121D5B461 CRC64;
     MEHPVFKRDP SEKSETERRE VPPLLKLALE LGPLLVFFFA NARGEMLIER FPILGSIGAP
     IFLATALFMA ATVIALAISW SMTRTLPIMP LVSGIVVLVF GALTLWLHND TFIKMKPTIV
     NTLFGGILLG GLFFGKSLLG YVFDSAFRLD AEGWRKLTLR WALFFIFLAI VNEIVWRNFS
     TDTWVSFKVW GIMPITIVFT LLQMPLIQKH SLTDEENTAS