ID   YCIB_BRUME              Reviewed;         200 AA.
AC   Q8YJF3;
DT   28-FEB-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Inner membrane-spanning protein YciB {ECO:0000255|HAMAP-Rule:MF_00189};
GN   Name=yciB {ECO:0000255|HAMAP-Rule:MF_00189}; OrderedLocusNames=BMEI0130;
OS   Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=224914;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=16M / ATCC 23456 / NCTC 10094;
RX   PubMed=11756688; DOI=10.1073/pnas.221575398;
RA   DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA   Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA   Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA   Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J.,
RA   Haselkorn R., Kyrpides N.C., Overbeek R.;
RT   "The genome sequence of the facultative intracellular pathogen Brucella
RT   melitensis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
CC   -!- FUNCTION: Plays a role in cell envelope biogenesis, maintenance of cell
CC       envelope integrity and membrane homeostasis. {ECO:0000255|HAMAP-
CC       Rule:MF_00189}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00189}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00189}.
CC   -!- SIMILARITY: Belongs to the YciB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00189}.
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DR   EMBL; AE008917; AAL51312.1; -; Genomic_DNA.
DR   PIR; AE3268; AE3268.
DR   AlphaFoldDB; Q8YJF3; -.
DR   STRING; 224914.BMEI0130; -.
DR   EnsemblBacteria; AAL51312; AAL51312; BMEI0130.
DR   KEGG; bme:BMEI0130; -.
DR   eggNOG; COG2917; Bacteria.
DR   OMA; AWVNFKL; -.
DR   Proteomes; UP000000419; Chromosome I.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00189; YciB; 1.
DR   InterPro; IPR006008; YciB.
DR   PANTHER; PTHR36917; PTHR36917; 1.
DR   Pfam; PF04279; IspA; 1.
DR   TIGRFAMs; TIGR00997; ispZ; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..200
FT                   /note="Inner membrane-spanning protein YciB"
FT                   /id="PRO_0000206525"
FT   TRANSMEM        1..21
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        66..86
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        103..123
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        136..156
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        167..187
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
SQ   SEQUENCE   200 AA;  22330 MW;  04A1E42F3418A8F0 CRC64;
     MPPLLKLALE LGPLLVFFFA NARGEMLIER FPILGSIGAP IFLATALFMA ATVIALAISW
     SMTRTLAIMP LVSGIVVLVF GALTLWLHND TFIKMKPTIV NTLFGGILLG GLFFGKSLLG
     YVFDSAFRLD AEGWRKLTLR WGLFFIFLAI VNEIVWRNFS TDTWVSFKVW GIMPITIVFT
     LLQMPLIQKH SLTDEENTAS