YCIB_HAEI8
ID YCIB_HAEI8 Reviewed; 185 AA.
AC Q4QM74;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Inner membrane-spanning protein YciB {ECO:0000255|HAMAP-Rule:MF_00189};
GN Name=yciB {ECO:0000255|HAMAP-Rule:MF_00189}; OrderedLocusNames=NTHI0991;
OS Haemophilus influenzae (strain 86-028NP).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC Pasteurellaceae; Haemophilus.
OX NCBI_TaxID=281310;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=86-028NP;
RX PubMed=15968074; DOI=10.1128/jb.187.13.4627-4636.2005;
RA Harrison A., Dyer D.W., Gillaspy A., Ray W.C., Mungur R., Carson M.B.,
RA Zhong H., Gipson J., Gipson M., Johnson L.S., Lewis L., Bakaletz L.O.,
RA Munson R.S. Jr.;
RT "Genomic sequence of an otitis media isolate of nontypeable Haemophilus
RT influenzae: comparative study with H. influenzae serotype d, strain KW20.";
RL J. Bacteriol. 187:4627-4636(2005).
CC -!- FUNCTION: Plays a role in cell envelope biogenesis, maintenance of cell
CC envelope integrity and membrane homeostasis. {ECO:0000255|HAMAP-
CC Rule:MF_00189}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00189}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_00189}.
CC -!- SIMILARITY: Belongs to the YciB family. {ECO:0000255|HAMAP-
CC Rule:MF_00189}.
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DR EMBL; CP000057; AAX87873.1; -; Genomic_DNA.
DR RefSeq; WP_011272232.1; NC_007146.2.
DR AlphaFoldDB; Q4QM74; -.
DR EnsemblBacteria; AAX87873; AAX87873; NTHI0991.
DR KEGG; hit:NTHI0991; -.
DR HOGENOM; CLU_089554_2_0_6; -.
DR OMA; AWVNFKL; -.
DR OrthoDB; 1886685at2; -.
DR Proteomes; UP000002525; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00189; YciB; 1.
DR InterPro; IPR006008; YciB.
DR PANTHER; PTHR36917; PTHR36917; 1.
DR Pfam; PF04279; IspA; 1.
DR TIGRFAMs; TIGR00997; ispZ; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..185
FT /note="Inner membrane-spanning protein YciB"
FT /id="PRO_1000021014"
FT TRANSMEM 27..47
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT TRANSMEM 53..73
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT TRANSMEM 118..138
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT TRANSMEM 149..169
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
SQ SEQUENCE 185 AA; 21163 MW; EC95204A42C02270 CRC64;
MKQLLDFIPL ILFFITYKLG GVREAAIVLV VATILQIVIL KWKYGIVEKQ QKIMASAVVF
FGLLTAYFNE IRYLQWKVTI INGLFAIVLL VAQFQFKTPL IKKLLGKELQ LPEKAWNTLN
LGWALFFIIC MLVNIYISHN MSEEAWVDFK SFGIIGMTVI ATIISGVYIY RYLPKDGSNS
KDGEK