YCIB_LEGPH
ID YCIB_LEGPH Reviewed; 181 AA.
AC Q5ZVZ5;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 78.
DE RecName: Full=Inner membrane-spanning protein YciB {ECO:0000255|HAMAP-Rule:MF_00189};
GN Name=yciB {ECO:0000255|HAMAP-Rule:MF_00189}; OrderedLocusNames=lpg1293;
OS Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC
OS 33152 / DSM 7513).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Legionellales;
OC Legionellaceae; Legionella.
OX NCBI_TaxID=272624;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Philadelphia 1 / ATCC 33152 / DSM 7513;
RX PubMed=15448271; DOI=10.1126/science.1099776;
RA Chien M., Morozova I., Shi S., Sheng H., Chen J., Gomez S.M., Asamani G.,
RA Hill K., Nuara J., Feder M., Rineer J., Greenberg J.J., Steshenko V.,
RA Park S.H., Zhao B., Teplitskaya E., Edwards J.R., Pampou S., Georghiou A.,
RA Chou I.-C., Iannuccilli W., Ulz M.E., Kim D.H., Geringer-Sameth A.,
RA Goldsberry C., Morozov P., Fischer S.G., Segal G., Qu X., Rzhetsky A.,
RA Zhang P., Cayanis E., De Jong P.J., Ju J., Kalachikov S., Shuman H.A.,
RA Russo J.J.;
RT "The genomic sequence of the accidental pathogen Legionella pneumophila.";
RL Science 305:1966-1968(2004).
CC -!- FUNCTION: Plays a role in cell envelope biogenesis, maintenance of cell
CC envelope integrity and membrane homeostasis. {ECO:0000255|HAMAP-
CC Rule:MF_00189}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00189}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_00189}.
CC -!- SIMILARITY: Belongs to the YciB family. {ECO:0000255|HAMAP-
CC Rule:MF_00189}.
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DR EMBL; AE017354; AAU27376.1; -; Genomic_DNA.
DR RefSeq; WP_010947024.1; NC_002942.5.
DR RefSeq; YP_095323.1; NC_002942.5.
DR AlphaFoldDB; Q5ZVZ5; -.
DR STRING; 272624.lpg1293; -.
DR PaxDb; Q5ZVZ5; -.
DR EnsemblBacteria; AAU27376; AAU27376; lpg1293.
DR GeneID; 66490427; -.
DR KEGG; lpn:lpg1293; -.
DR PATRIC; fig|272624.6.peg.1361; -.
DR eggNOG; COG2917; Bacteria.
DR HOGENOM; CLU_089554_2_0_6; -.
DR OMA; AWVNFKL; -.
DR Proteomes; UP000000609; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00189; YciB; 1.
DR InterPro; IPR006008; YciB.
DR PANTHER; PTHR36917; PTHR36917; 1.
DR Pfam; PF04279; IspA; 1.
DR TIGRFAMs; TIGR00997; ispZ; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix.
FT CHAIN 1..181
FT /note="Inner membrane-spanning protein YciB"
FT /id="PRO_1000021025"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT TRANSMEM 54..74
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT TRANSMEM 81..101
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT TRANSMEM 119..139
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT TRANSMEM 149..169
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
SQ SEQUENCE 181 AA; 21275 MW; 15C903C82F731C8D CRC64;
MKLLFDFFPI VLFFIVYKFF GIYTATAVAM VASLTQVAFY RLKFQHYEKM HLFSLAIIMV
LGGATLFFQN PWFIKWKPTG IYWLSALVFY GSSYIGSKPL IQKMMEANIN LTTKIWYRLN
LAWTLFFIVM GALNLYVAYH YDTDVWVNFK LFGGVGFTLL FVLIQAFYLT KHTDEKSFEK
Q