ID   YCIB_RICTY              Reviewed;         180 AA.
AC   Q68WY5;
DT   20-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 83.
DE   RecName: Full=Inner membrane-spanning protein YciB {ECO:0000255|HAMAP-Rule:MF_00189};
GN   Name=yciB {ECO:0000255|HAMAP-Rule:MF_00189}; OrderedLocusNames=RT0380;
OS   Rickettsia typhi (strain ATCC VR-144 / Wilmington).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; typhus group.
OX   NCBI_TaxID=257363;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC VR-144 / Wilmington;
RX   PubMed=15317790; DOI=10.1128/jb.186.17.5842-5855.2004;
RA   McLeod M.P., Qin X., Karpathy S.E., Gioia J., Highlander S.K., Fox G.E.,
RA   McNeill T.Z., Jiang H., Muzny D., Jacob L.S., Hawes A.C., Sodergren E.,
RA   Gill R., Hume J., Morgan M., Fan G., Amin A.G., Gibbs R.A., Hong C.,
RA   Yu X.-J., Walker D.H., Weinstock G.M.;
RT   "Complete genome sequence of Rickettsia typhi and comparison with sequences
RT   of other Rickettsiae.";
RL   J. Bacteriol. 186:5842-5855(2004).
CC   -!- FUNCTION: Plays a role in cell envelope biogenesis, maintenance of cell
CC       envelope integrity and membrane homeostasis. {ECO:0000255|HAMAP-
CC       Rule:MF_00189}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00189}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00189}.
CC   -!- SIMILARITY: Belongs to the YciB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00189}.
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DR   EMBL; AE017197; AAU03857.1; -; Genomic_DNA.
DR   RefSeq; WP_011190841.1; NC_006142.1.
DR   AlphaFoldDB; Q68WY5; -.
DR   SMR; Q68WY5; -.
DR   STRING; 257363.RT0380; -.
DR   EnsemblBacteria; AAU03857; AAU03857; RT0380.
DR   KEGG; rty:RT0380; -.
DR   eggNOG; COG2917; Bacteria.
DR   HOGENOM; CLU_089554_1_1_5; -.
DR   OMA; AWVNFKL; -.
DR   OrthoDB; 1886685at2; -.
DR   Proteomes; UP000000604; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00189; YciB; 1.
DR   InterPro; IPR006008; YciB.
DR   PANTHER; PTHR36917; PTHR36917; 1.
DR   Pfam; PF04279; IspA; 1.
DR   TIGRFAMs; TIGR00997; ispZ; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..180
FT                   /note="Inner membrane-spanning protein YciB"
FT                   /id="PRO_0000278052"
FT   TRANSMEM        4..24
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        25..45
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        49..69
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        118..138
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
SQ   SEQUENCE   180 AA;  20464 MW;  43DDC75EEC6F91EB CRC64;
     MLKLLSEIGP VIAFFAGFFY GGGIQSATLY MLITSIICIT LCYIIDKKVS KLSIISSTVL
     FVSGIITLIS GDSMYIKIKP TILYVIFGII FLMSGIRKNP FIKYALESIV RLKEESWIIL
     SYRTAAFFFF MAVVNEVVWR NFSDETWVKF KVFGVIPITF IFILLQLPLL LKNKLPDSKI