ID   YCIB_YERPE              Reviewed;         180 AA.
AC   Q8ZEH5; Q0WEW9;
DT   15-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 126.
DE   RecName: Full=Inner membrane-spanning protein YciB {ECO:0000255|HAMAP-Rule:MF_00189};
GN   Name=yciB {ECO:0000255|HAMAP-Rule:MF_00189};
GN   OrderedLocusNames=YPO2196, y2040, YP_1995;
OS   Yersinia pestis.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Yersiniaceae; Yersinia.
OX   NCBI_TaxID=632;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CO-92 / Biovar Orientalis;
RX   PubMed=11586360; DOI=10.1038/35097083;
RA   Parkhill J., Wren B.W., Thomson N.R., Titball R.W., Holden M.T.G.,
RA   Prentice M.B., Sebaihia M., James K.D., Churcher C.M., Mungall K.L.,
RA   Baker S., Basham D., Bentley S.D., Brooks K., Cerdeno-Tarraga A.-M.,
RA   Chillingworth T., Cronin A., Davies R.M., Davis P., Dougan G., Feltwell T.,
RA   Hamlin N., Holroyd S., Jagels K., Karlyshev A.V., Leather S., Moule S.,
RA   Oyston P.C.F., Quail M.A., Rutherford K.M., Simmonds M., Skelton J.,
RA   Stevens K., Whitehead S., Barrell B.G.;
RT   "Genome sequence of Yersinia pestis, the causative agent of plague.";
RL   Nature 413:523-527(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIM10+ / Biovar Mediaevalis;
RX   PubMed=12142430; DOI=10.1128/jb.184.16.4601-4611.2002;
RA   Deng W., Burland V., Plunkett G. III, Boutin A., Mayhew G.F., Liss P.,
RA   Perna N.T., Rose D.J., Mau B., Zhou S., Schwartz D.C., Fetherston J.D.,
RA   Lindler L.E., Brubaker R.R., Plano G.V., Straley S.C., McDonough K.A.,
RA   Nilles M.L., Matson J.S., Blattner F.R., Perry R.D.;
RT   "Genome sequence of Yersinia pestis KIM.";
RL   J. Bacteriol. 184:4601-4611(2002).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=91001 / Biovar Mediaevalis;
RX   PubMed=15368893; DOI=10.1093/dnares/11.3.179;
RA   Song Y., Tong Z., Wang J., Wang L., Guo Z., Han Y., Zhang J., Pei D.,
RA   Zhou D., Qin H., Pang X., Han Y., Zhai J., Li M., Cui B., Qi Z., Jin L.,
RA   Dai R., Chen F., Li S., Ye C., Du Z., Lin W., Wang J., Yu J., Yang H.,
RA   Wang J., Huang P., Yang R.;
RT   "Complete genome sequence of Yersinia pestis strain 91001, an isolate
RT   avirulent to humans.";
RL   DNA Res. 11:179-197(2004).
CC   -!- FUNCTION: Plays a role in cell envelope biogenesis, maintenance of cell
CC       envelope integrity and membrane homeostasis. {ECO:0000255|HAMAP-
CC       Rule:MF_00189}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_00189}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_00189}.
CC   -!- SIMILARITY: Belongs to the YciB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00189}.
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DR   EMBL; AL590842; CAL20826.1; -; Genomic_DNA.
DR   EMBL; AE009952; AAM85606.1; -; Genomic_DNA.
DR   EMBL; AE017042; AAS62212.1; -; Genomic_DNA.
DR   PIR; AG0267; AG0267.
DR   RefSeq; WP_002210640.1; NZ_WUCM01000001.1.
DR   RefSeq; YP_002347169.1; NC_003143.1.
DR   AlphaFoldDB; Q8ZEH5; -.
DR   STRING; 214092.YPO2196; -.
DR   PaxDb; Q8ZEH5; -.
DR   DNASU; 1146987; -.
DR   EnsemblBacteria; AAM85606; AAM85606; y2040.
DR   EnsemblBacteria; AAS62212; AAS62212; YP_1995.
DR   GeneID; 66841447; -.
DR   KEGG; ype:YPO2196; -.
DR   KEGG; ypk:y2040; -.
DR   KEGG; ypm:YP_1995; -.
DR   PATRIC; fig|214092.21.peg.2592; -.
DR   eggNOG; COG2917; Bacteria.
DR   HOGENOM; CLU_089554_2_0_6; -.
DR   OMA; AWVNFKL; -.
DR   Proteomes; UP000000815; Chromosome.
DR   Proteomes; UP000001019; Chromosome.
DR   Proteomes; UP000002490; Chromosome.
DR   GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR   HAMAP; MF_00189; YciB; 1.
DR   InterPro; IPR006008; YciB.
DR   PANTHER; PTHR36917; PTHR36917; 1.
DR   Pfam; PF04279; IspA; 1.
DR   TIGRFAMs; TIGR00997; ispZ; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..180
FT                   /note="Inner membrane-spanning protein YciB"
FT                   /id="PRO_0000206556"
FT   TRANSMEM        22..42
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        50..70
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        121..141
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
FT   TRANSMEM        149..169
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00189"
SQ   SEQUENCE   180 AA;  20875 MW;  1295C4E7E5CB5D2F CRC64;
     MKQLLDFLPL VVFFIFYKMY DIFVASGALI VATLVALAFT WLKYRKVEKM TLVTAAMVLV
     FGTLTLAFHS DLFIKWKVTV LYVLFALALL VSQWVMKKPL IQRMLGKELT LPDKVWSTLN
     LSWAIFFLVC GLLNIYVAFW LPQDIWVNFK VFGLTALTLI FTLISGVYIY RHMPEEQKKS