ID   YCIC_SALTI              Reviewed;         247 AA.
AC   Q8Z7E3;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=UPF0259 membrane protein YciC;
GN   Name=yciC; OrderedLocusNames=STY1317, t1646;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0259 family. {ECO:0000305}.
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DR   EMBL; AL513382; CAD08398.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO69273.1; -; Genomic_DNA.
DR   RefSeq; NP_455764.1; NC_003198.1.
DR   RefSeq; WP_000028506.1; NZ_WSUR01000006.1.
DR   AlphaFoldDB; Q8Z7E3; -.
DR   STRING; 220341.16502441; -.
DR   EnsemblBacteria; AAO69273; AAO69273; t1646.
DR   KEGG; stt:t1646; -.
DR   KEGG; sty:STY1317; -.
DR   PATRIC; fig|220341.7.peg.1324; -.
DR   eggNOG; ENOG502Z96Y; Bacteria.
DR   HOGENOM; CLU_073287_0_0_6; -.
DR   OMA; FFRNQFV; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01067; UPF0259; 1.
DR   InterPro; IPR009627; UPF0259.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..247
FT                   /note="UPF0259 membrane protein YciC"
FT                   /id="PRO_0000206518"
FT   TOPO_DOM        1..19
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        41..86
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        87..107
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        108..117
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        118..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        141..151
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        173..193
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        194..214
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        215..218
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        219..239
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        240..247
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   247 AA;  26343 MW;  B90B6CFD2B702B22 CRC64;
     MSITAKSVYR DAGNFFRNQF ITILLVSLLC AFITVVLGHA FSPSDAQIAQ LSEGEHLAGS
     AGLFELVQNM TPEQQQILLR ASAASTFSGL IGNAILAGGI ILMIQLVSAG HRVSALRAIG
     ASAPALPKLF ILIFLTTLLV QIGIMLIVVP GIIMAIVLAL APVMLVEEKM GVFAAMRSSM
     RLAWANMKLV APAVIGWLLA KTLLLLFAPS FAVLTPNVGA VLANTLSNLI SAVLLIYLFR
     LYMLIRQ