ID   YCIC_SHIFL              Reviewed;         247 AA.
AC   Q83LC9;
DT   11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   11-JUL-2003, sequence version 2.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=UPF0259 membrane protein YciC;
GN   Name=yciC; OrderedLocusNames=SF1258, S1344;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the UPF0259 family. {ECO:0000305}.
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DR   EMBL; AE005674; AAN42871.2; -; Genomic_DNA.
DR   EMBL; AE014073; AAP16756.1; -; Genomic_DNA.
DR   RefSeq; NP_707164.2; NC_004337.2.
DR   RefSeq; WP_000028536.1; NZ_WPGW01000009.1.
DR   AlphaFoldDB; Q83LC9; -.
DR   STRING; 198214.SF1258; -.
DR   EnsemblBacteria; AAN42871; AAN42871; SF1258.
DR   EnsemblBacteria; AAP16756; AAP16756; S1344.
DR   GeneID; 1024190; -.
DR   GeneID; 58388667; -.
DR   KEGG; sfl:SF1258; -.
DR   KEGG; sfx:S1344; -.
DR   PATRIC; fig|198214.7.peg.1478; -.
DR   HOGENOM; CLU_073287_0_0_6; -.
DR   OMA; FFRNQFV; -.
DR   OrthoDB; 1620971at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   HAMAP; MF_01067; UPF0259; 1.
DR   InterPro; IPR009627; UPF0259.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix.
FT   CHAIN           1..247
FT                   /note="UPF0259 membrane protein YciC"
FT                   /id="PRO_0000206520"
FT   TOPO_DOM        1..19
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        20..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        41..89
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        90..110
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        111..117
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        118..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        141..151
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        173..186
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        187..209
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        210..224
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        225..245
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        246..247
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   247 AA;  26505 MW;  32B93E8B1019DCC4 CRC64;
     MSITAQSVYR DTGNFFRNQF MTILLVSLLC AFITVVLGHV FSPSDAQLAQ LNDGVPVSGS
     SGLFDLVQNM SPEQQQILLQ ASAASTFSEL IGNAILAGGV ILIIQLVSAG QRVSALRAIG
     ASAPILPKLF ILIFLTTLLV QIGIMLVVVP GIIMAILLAL APVMLVQDKM GIFASMRSSM
     RLTWANMRLV APAVLSWLLA KTLLLLFASS FAALTPEIGA VLANTLSNLI SAILLIYLFR
     LYMLIRQ