ID   YCJW_ECOLI              Reviewed;         332 AA.
AC   P77615;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 147.
DE   RecName: Full=Uncharacterized HTH-type transcriptional regulator YcjW;
GN   Name=ycjW; OrderedLocusNames=b1320, JW1313;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA   Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA   Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA   Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA   Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA   Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA   Wada C., Yamamoto Y., Horiuchi T.;
RT   "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 28.0-40.1 min region on the linkage map.";
RL   DNA Res. 3:363-377(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U00096; AAC74402.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA14901.1; -; Genomic_DNA.
DR   PIR; C64881; C64881.
DR   RefSeq; NP_415836.1; NC_000913.3.
DR   RefSeq; WP_000075375.1; NZ_SSZK01000012.1.
DR   AlphaFoldDB; P77615; -.
DR   SMR; P77615; -.
DR   BioGRID; 4260147; 10.
DR   BioGRID; 850242; 1.
DR   DIP; DIP-11614N; -.
DR   IntAct; P77615; 4.
DR   STRING; 511145.b1320; -.
DR   jPOST; P77615; -.
DR   PaxDb; P77615; -.
DR   PRIDE; P77615; -.
DR   EnsemblBacteria; AAC74402; AAC74402; b1320.
DR   EnsemblBacteria; BAA14901; BAA14901; BAA14901.
DR   GeneID; 945875; -.
DR   KEGG; ecj:JW1313; -.
DR   KEGG; eco:b1320; -.
DR   PATRIC; fig|1411691.4.peg.958; -.
DR   EchoBASE; EB3679; -.
DR   eggNOG; COG1609; Bacteria.
DR   HOGENOM; CLU_037628_6_2_6; -.
DR   InParanoid; P77615; -.
DR   OMA; YNRYDAY; -.
DR   PhylomeDB; P77615; -.
DR   BioCyc; EcoCyc:G6658-MON; -.
DR   PRO; PR:P77615; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IDA:EcoCyc.
DR   GO; GO:0006974; P:cellular response to DNA damage stimulus; IMP:EcoCyc.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:EcoCyc.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   CDD; cd01392; HTH_LacI; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR000843; HTH_LacI.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   InterPro; IPR001761; Peripla_BP/Lac1_sug-bd_dom.
DR   InterPro; IPR028082; Peripla_BP_I.
DR   Pfam; PF00356; LacI; 1.
DR   Pfam; PF00532; Peripla_BP_1; 1.
DR   PRINTS; PR00036; HTHLACI.
DR   SMART; SM00354; HTH_LACI; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   SUPFAM; SSF53822; SSF53822; 1.
DR   PROSITE; PS00356; HTH_LACI_1; 1.
DR   PROSITE; PS50932; HTH_LACI_2; 1.
PE   4: Predicted;
KW   DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..332
FT                   /note="Uncharacterized HTH-type transcriptional regulator
FT                   YcjW"
FT                   /id="PRO_0000108009"
FT   DOMAIN          1..57
FT                   /note="HTH lacI-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
FT   DNA_BIND        5..24
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00111"
SQ   SEQUENCE   332 AA;  36134 MW;  F9779C862327F40D CRC64;
     MSPTIYDIAR VAGVSKSTVS RVLNKQTNIS PEAREKVLRA IEELQYQPNK LARALTSSGF
     DAIMVISTRS TKTTAGNPFF SEVLHAITAK AEEEGFDVIL QTSHNPAEDL QKCESKIKQK
     MIKGIIMLSS PADESFFAQL DKYDIPVVVI GKVEGQYAHV YSVDTDNFGD SIALTDALIE
     SGHQNIACLH APLDVHVSVD RVNGYKQSLA AHNIAVRDEW IVDGGYTHET ALKAARQLLS
     QSPLPEAVFA TDSLKLMSIY RAAAEKNIAI PQQLAVVGYS NETLSFILTP APGGIDVPTQ
     ELGQQSCELL FRLISGKPSP QNITVATHMT LK