YCLN_BACSU
ID YCLN_BACSU Reviewed; 316 AA.
AC P94418; Q797P2;
DT 20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1997, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=Petrobactin import system permease protein YclN {ECO:0000305};
GN Name=yclN; OrderedLocusNames=BSU03800;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=8969502; DOI=10.1099/13500872-142-11-3047;
RA Yamane K., Kumano M., Kurita K.;
RT "The 25 degrees-36 degrees region of the Bacillus subtilis chromosome:
RT determination of the sequence of a 146 kb segment and identification of 113
RT genes.";
RL Microbiology 142:3047-3056(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP FUNCTION, SUBUNIT, AND DISRUPTION PHENOTYPE.
RC STRAIN=168;
RX PubMed=19955416; DOI=10.1073/pnas.0904793106;
RA Zawadzka A.M., Kim Y., Maltseva N., Nichiporuk R., Fan Y., Joachimiak A.,
RA Raymond K.N.;
RT "Characterization of a Bacillus subtilis transporter for petrobactin, an
RT anthrax stealth siderophore.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:21854-21859(2009).
CC -!- FUNCTION: Part of the ABC transporter complex YclNOPQ involved in
CC uptake of ferric-petrobactin. Petrobactin is a photoreactive 3,4-
CC catecholate siderophore produced by many members of the B.cereus group,
CC including B.anthracis. Probably responsible for the translocation of
CC the substrate across the membrane. {ECO:0000269|PubMed:19955416}.
CC -!- SUBUNIT: The complex is composed of two ATP-binding proteins (YclP),
CC two transmembrane proteins (YclN and YclO) and a solute-binding protein
CC (YclQ). {ECO:0000305|PubMed:19955416}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000255}.
CC -!- DISRUPTION PHENOTYPE: Disruption mutants are unable to use petrobactin
CC for iron delivery and growth. {ECO:0000269|PubMed:19955416}.
CC -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC permease family. FecCD subfamily. {ECO:0000305}.
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DR EMBL; D50453; BAA09012.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB12188.1; -; Genomic_DNA.
DR PIR; B69763; B69763.
DR RefSeq; NP_388262.1; NC_000964.3.
DR RefSeq; WP_003234491.1; NZ_JNCM01000031.1.
DR AlphaFoldDB; P94418; -.
DR SMR; P94418; -.
DR STRING; 224308.BSU03800; -.
DR PaxDb; P94418; -.
DR EnsemblBacteria; CAB12188; CAB12188; BSU_03800.
DR GeneID; 938273; -.
DR KEGG; bsu:BSU03800; -.
DR PATRIC; fig|224308.179.peg.403; -.
DR eggNOG; COG4606; Bacteria.
DR InParanoid; P94418; -.
DR OMA; WFAGSFT; -.
DR PhylomeDB; P94418; -.
DR BioCyc; BSUB:BSU03800-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0033214; P:siderophore-dependent iron import into cell; IBA:GO_Central.
DR Gene3D; 1.10.3470.10; -; 1.
DR InterPro; IPR037294; ABC_BtuC-like.
DR InterPro; IPR000522; ABC_transptr_permease_BtuC.
DR PANTHER; PTHR30472; PTHR30472; 1.
DR Pfam; PF01032; FecCD; 1.
DR SUPFAM; SSF81345; SSF81345; 1.
PE 1: Evidence at protein level;
KW Cell membrane; Ion transport; Iron; Iron transport; Membrane;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..316
FT /note="Petrobactin import system permease protein YclN"
FT /id="PRO_0000359514"
FT TRANSMEM 5..25
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 49..69
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 94..114
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 181..201
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 268..288
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 290..310
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 316 AA; 34899 MW; 70C1C696389C8834 CRC64;
MKLRYLFILL IILAVTSVFI GVEDLSPLDL FDLSKQEAST LFASRLPRLI SIVIAGLSMS
ICGLIMQQIS RNKFVSPTTA GTMDWARLGI LISLLLFTSA SPLIKMLVAF VFALAGNFLF
MKILERIKFN DTIFIPLVGL MLGNIVSSIA TFIAYKYDLI QNVSSWLQGD FSLVVKGRYE
LLYLSIPLVI IAYVYADKFT LAGMGESFSV NLGLKYKRVV NIGLIIVSLI TSLVILTVGM
LPFLGLIIPN IVSIYRGDNL KSSLPHTVLL GAVFVLFCDI LGRIIIFPYE ISIGLMVGII
GSGIFLFMLL RRKAYA
