YCPE_SCHPO
ID YCPE_SCHPO Reviewed; 687 AA.
AC O74520;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 2.
DT 25-MAY-2022, entry version 107.
DE RecName: Full=Uncharacterized membrane protein C663.14c;
DE Flags: Precursor;
GN ORFNames=SPCC663.14c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the transient receptor potential (TRP) ion
CC channel family. {ECO:0000305}.
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DR EMBL; CU329672; CAA20374.2; -; Genomic_DNA.
DR PIR; T41545; T41545.
DR RefSeq; NP_588275.1; NM_001023265.1.
DR AlphaFoldDB; O74520; -.
DR BioGRID; 276076; 30.
DR STRING; 4896.SPCC663.14c.1; -.
DR SwissPalm; O74520; -.
DR PaxDb; O74520; -.
DR EnsemblFungi; SPCC663.14c.1; SPCC663.14c.1:pep; SPCC663.14c.
DR GeneID; 2539514; -.
DR KEGG; spo:SPCC663.14c; -.
DR PomBase; SPCC663.14c; -.
DR VEuPathDB; FungiDB:SPCC663.14c; -.
DR eggNOG; ENOG502R5MY; Eukaryota.
DR HOGENOM; CLU_399638_0_0_1; -.
DR InParanoid; O74520; -.
DR OMA; WASNFAW; -.
DR PhylomeDB; O74520; -.
DR PRO; PR:O74520; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0032153; C:cell division site; IDA:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IDA:PomBase.
DR GO; GO:0022857; F:transmembrane transporter activity; ISM:PomBase.
DR GO; GO:0009272; P:fungal-type cell wall biogenesis; IBA:GO_Central.
DR GO; GO:0055085; P:transmembrane transport; ISM:PomBase.
DR InterPro; IPR010308; TRP_C.
DR InterPro; IPR040241; TRP_Flc/Pkd2-like.
DR InterPro; IPR032800; TRP_N.
DR PANTHER; PTHR31145; PTHR31145; 4.
DR Pfam; PF06011; TRP; 1.
DR Pfam; PF14558; TRP_N; 1.
DR SMART; SM01320; TRP_N; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix;
KW Transport.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..687
FT /note="Uncharacterized membrane protein C663.14c"
FT /id="PRO_0000372621"
FT TRANSMEM 186..206
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 331..351
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 376..396
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 407..427
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 469..489
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 498..518
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 524..544
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 553..573
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 632..653
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 636..653
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 687 AA; 77218 MW; 2FDA946ED93F7359 CRC64;
MKLILLAYFA VLSNILSSVE GRVRYSKRPN HKLGTAEYAE CMSNAPIVFN RFDASYYTRN
LSVVFNILGY SSVDANVTFD IIVEAYGEQR ARFTFDPCEI NLNTVCPVAR DTAITTQGIL
PVSPQDVQMI PKIAWGIPDF EGLVRFRMYR SEDIAASSID NSTPLACMIA TLNNGHTFKN
KVVKALSGTA LALSIAGVLG FYVIGMEHST YLTRQVFINS VPSLQHMGEL LQCIAFTGAI
GITQPKVLVA WASNFAWILG FITNKEIENS LESFRKHSNG NLSSPKIGGV HRRDAVATNP
QSPIPGFYHG FQGLATEVGT LTTNLFTLTL IWFLISLAIA GGIVIIFVLI IKFLRQTRII
AKSSCDYITR YWFRVLFNAC MRWVLVCWPV LVTMIIYQFT LREAYGPVIL AALLLALLFG
LFLWLTIKVI RVITTSGLSN EDNPETLISD PKIYTWWGWL YLDLKERRWL YVYACFAHYF
SFALVLALVQ QFAKIQTILL FVIEIISFIL LAVFRPFVGF KNSFCVFLVA LTRVVSFALL
IPIAFDLAII PKVIIAIILI IIQGLVFSFM ALWSLWNFIT MLGTAWPAIS YTVPWLRRLI
DEYQRQLHID FENPAVSASE KLSTEEIIPQ ESNFEEPSTT KKEGNVDTKE DGNDDVFSLV
NASPMRPAST IPSHSCDNGI NEMQRTV
