YCSG_BACSU
ID YCSG_BACSU Reviewed; 404 AA.
AC P42964; P42965; P94436;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 4.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=Uncharacterized membrane protein YcsG;
GN Name=ycsG; Synonyms=ycsH; OrderedLocusNames=BSU04060;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=8574415; DOI=10.1099/13500872-141-12-3241;
RA Akagawa E., Kurita K., Sugawara T., Nakamura K., Kasahara Y., Ogasawara N.,
RA Yamane K.;
RT "Determination of a 17,484 bp nucleotide sequence around the 39 degrees
RT region of the Bacillus subtilis chromosome and similarity analysis of the
RT products of putative ORFs.";
RL Microbiology 141:3241-3245(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
RN [3]
RP SEQUENCE REVISION TO 92; 146 AND 246.
RX PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT 168 reference genome a decade later.";
RL Microbiology 155:1758-1775(2009).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 84-404.
RC STRAIN=168;
RX PubMed=8969502; DOI=10.1099/13500872-142-11-3047;
RA Yamane K., Kumano M., Kurita K.;
RT "The 25 degrees-36 degrees region of the Bacillus subtilis chromosome:
RT determination of the sequence of a 146 kb segment and identification of 113
RT genes.";
RL Microbiology 142:3047-3056(1996).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the NRAMP family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA07358.1; Type=Frameshift; Evidence={ECO:0000305};
CC Sequence=BAA07359.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; D38161; BAA07358.1; ALT_FRAME; Genomic_DNA.
DR EMBL; D38161; BAA07359.1; ALT_INIT; Genomic_DNA.
DR EMBL; AL009126; CAB12214.3; -; Genomic_DNA.
DR EMBL; D50453; BAA09037.1; -; Genomic_DNA.
DR PIR; E69765; E69765.
DR RefSeq; NP_388288.3; NC_000964.3.
DR RefSeq; WP_003234422.1; NZ_JNCM01000031.1.
DR AlphaFoldDB; P42964; -.
DR SMR; P42964; -.
DR STRING; 224308.BSU04060; -.
DR TCDB; 2.A.55.3.2; the metal ion (mn(2+)-iron) transporter (nramp) family.
DR PaxDb; P42964; -.
DR EnsemblBacteria; CAB12214; CAB12214; BSU_04060.
DR GeneID; 938257; -.
DR KEGG; bsu:BSU04060; -.
DR PATRIC; fig|224308.179.peg.432; -.
DR eggNOG; COG1914; Bacteria.
DR InParanoid; P42964; -.
DR OMA; QTNVWRI; -.
DR PhylomeDB; P42964; -.
DR BioCyc; BSUB:BSU04060-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015086; F:cadmium ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0005384; F:manganese ion transmembrane transporter activity; IBA:GO_Central.
DR InterPro; IPR001046; NRAMP_fam.
DR PANTHER; PTHR11706; PTHR11706; 1.
DR Pfam; PF01566; Nramp; 1.
PE 3: Inferred from homology;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..404
FT /note="Uncharacterized membrane protein YcsG"
FT /id="PRO_0000099775"
FT TRANSMEM 15..35
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 84..104
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 121..141
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 154..174
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 187..207
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 279..299
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 316..336
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 338..358
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 373..393
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CONFLICT 92
FT /note="F -> S (in Ref. 1; BAA07358 and 4; BAA09037)"
FT /evidence="ECO:0000305"
FT CONFLICT 146
FT /note="K -> I (in Ref. 1; BAA07358/BAA07359 and 4;
FT BAA09037)"
FT /evidence="ECO:0000305"
FT CONFLICT 246
FT /note="L -> F (in Ref. 1; BAA07359 and 4; BAA09037)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 404 AA; 42134 MW; 9B98F28935F7F88A CRC64;
MEQQKKTAGK KAGSWSLLMG AAFLMATSAI GPGFLTQTAT FTNTLAASFG FVILISIILD
IFAQTNVWRI IAVSGKRGQE IANMVLPGLG YFIAILVVLG GLAFNIGNIG GAGLGLQVLF
GITPETGALI SAVIAILIFV IKEAGKAMDR FTQIAGFVMI ILTVYVAATT APPVGQAVAN
TFVPEHISIF AIVTLVGGTV GGYITFAGGH RLLDAGIKGK ESIPQVTKSS VVGILITSVM
RIALFLAVLG VVSKGLHIDE SNPAASVFKL AAGNVGYKIF GLIMWSAAIT SVIGAAYTSV
SFFKTFSPKI EKNSRGIIIG FIVVSTLAFV TIGQPAKILV LVGSLNGLIL PIALGTLLVA
AYKKNIVGDY KHPLWLTSTG ALVVIVMAVM GIYTLCTQLP QLWS
