CB015_HUMAN
ID CB015_HUMAN Reviewed; 91 AA.
AC Q8WU43;
DT 05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 23-FEB-2022, sequence version 2.
DT 03-AUG-2022, entry version 114.
DE RecName: Full=Uncharacterized protein C2orf15 {ECO:0000305};
GN Name=C2orf15 {ECO:0000312|HGNC:HGNC:28436};
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15815621; DOI=10.1038/nature03466;
RA Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA Wilson R.K.;
RT "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT 4.";
RL Nature 434:724-731(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Placenta;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q8WU43; Q15109: AGER; NbExp=3; IntAct=EBI-12904676, EBI-1646426;
CC Q8WU43; P51808: DYNLT3; NbExp=3; IntAct=EBI-12904676, EBI-743027;
CC Q8WU43; P15311: EZR; NbExp=3; IntAct=EBI-12904676, EBI-1056902;
CC Q8WU43; Q16512: PKN1; NbExp=3; IntAct=EBI-12904676, EBI-602382;
CC Q8WU43; P31930: UQCRC1; NbExp=3; IntAct=EBI-12904676, EBI-1052596;
CC -!- SEQUENCE CAUTION:
CC Sequence=AAH21264.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC092587; AAX88926.1; -; Genomic_DNA.
DR EMBL; BC021264; AAH21264.1; ALT_INIT; mRNA.
DR CCDS; CCDS2038.1; -.
DR RefSeq; NP_001304921.1; NM_001317992.1.
DR RefSeq; NP_653307.1; NM_144706.3.
DR AlphaFoldDB; Q8WU43; -.
DR BioGRID; 127311; 1.
DR IntAct; Q8WU43; 5.
DR STRING; 9606.ENSP00000302202; -.
DR iPTMnet; Q8WU43; -.
DR PhosphoSitePlus; Q8WU43; -.
DR BioMuta; C2orf15; -.
DR EPD; Q8WU43; -.
DR MassIVE; Q8WU43; -.
DR MaxQB; Q8WU43; -.
DR PeptideAtlas; Q8WU43; -.
DR PRIDE; Q8WU43; -.
DR ProteomicsDB; 74631; -.
DR Antibodypedia; 71553; 39 antibodies from 8 providers.
DR DNASU; 150590; -.
DR Ensembl; ENST00000409684.2; ENSP00000386654.2; ENSG00000273045.7.
DR Ensembl; ENST00000650052.2; ENSP00000497775.2; ENSG00000273045.7.
DR GeneID; 150590; -.
DR KEGG; hsa:150590; -.
DR MANE-Select; ENST00000650052.2; ENSP00000497775.2; NM_144706.4; NP_653307.2.
DR UCSC; uc002szk.4; human.
DR CTD; 150590; -.
DR GeneCards; C2orf15; -.
DR HGNC; HGNC:28436; C2orf15.
DR HPA; ENSG00000273045; Low tissue specificity.
DR neXtProt; NX_Q8WU43; -.
DR OpenTargets; ENSG00000273045; -.
DR PharmGKB; PA134861678; -.
DR VEuPathDB; HostDB:ENSG00000273045; -.
DR eggNOG; ENOG502RWG5; Eukaryota.
DR GeneTree; ENSGT00390000000424; -.
DR HOGENOM; CLU_2090328_0_0_1; -.
DR InParanoid; Q8WU43; -.
DR OrthoDB; 1456667at2759; -.
DR PathwayCommons; Q8WU43; -.
DR SignaLink; Q8WU43; -.
DR BioGRID-ORCS; 150590; 11 hits in 1047 CRISPR screens.
DR GenomeRNAi; 150590; -.
DR Pharos; Q8WU43; Tdark.
DR PRO; PR:Q8WU43; -.
DR Proteomes; UP000005640; Chromosome 2.
DR RNAct; Q8WU43; protein.
DR Bgee; ENSG00000273045; Expressed in oocyte and 103 other tissues.
DR ExpressionAtlas; Q8WU43; baseline and differential.
DR Genevisible; Q8WU43; HS.
DR GO; GO:0003723; F:RNA binding; HDA:UniProtKB.
DR InterPro; IPR041537; DUF5547.
DR Pfam; PF17701; DUF5547; 1.
PE 1: Evidence at protein level;
KW Reference proteome.
FT CHAIN 1..91
FT /note="Uncharacterized protein C2orf15"
FT /id="PRO_0000089345"
SQ SEQUENCE 91 AA; 9962 MW; 0CFDA2CC04B7E55C CRC64;
MGFSLSKSAT QVSAIHMDSK VDDHLIRGTE KSRLEPATQL FQNTKKIRLE DTNQENFTRI
EGTGTGSLSG KALGSVVYVK ESDGLEMTDV E