YCTB_SCHPO
ID YCTB_SCHPO Reviewed; 476 AA.
AC P78813;
DT 29-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1999, sequence version 2.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=ENTH domain-containing protein C794.11c;
GN ORFNames=SPCC794.11c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 118-476.
RC STRAIN=PR745;
RX PubMed=9501991; DOI=10.1093/dnares/4.6.363;
RA Yoshioka S., Kato K., Nakai K., Okayama H., Nojima H.;
RT "Identification of open reading frames in Schizosaccharomyces pombe
RT cDNAs.";
RL DNA Res. 4:363-369(1997).
RN [3]
RP PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-173; SER-228; TYR-235;
RP SER-243; SER-244 AND SER-459, AND IDENTIFICATION BY MASS SPECTROMETRY.
RX PubMed=18257517; DOI=10.1021/pr7006335;
RA Wilson-Grady J.T., Villen J., Gygi S.P.;
RT "Phosphoproteome analysis of fission yeast.";
RL J. Proteome Res. 7:1088-1097(2008).
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DR EMBL; CU329672; CAA19138.1; -; Genomic_DNA.
DR EMBL; D89162; BAA13824.1; -; mRNA.
DR PIR; T41619; T41619.
DR PIR; T42524; T42524.
DR RefSeq; NP_587759.1; NM_001022752.2.
DR AlphaFoldDB; P78813; -.
DR SMR; P78813; -.
DR BioGRID; 275986; 36.
DR ELM; P78813; -.
DR IntAct; P78813; 1.
DR STRING; 4896.SPCC794.11c.1; -.
DR iPTMnet; P78813; -.
DR MaxQB; P78813; -.
DR PaxDb; P78813; -.
DR PRIDE; P78813; -.
DR EnsemblFungi; SPCC794.11c.1; SPCC794.11c.1:pep; SPCC794.11c.
DR GeneID; 2539421; -.
DR KEGG; spo:SPCC794.11c; -.
DR PomBase; SPCC794.11c; -.
DR VEuPathDB; FungiDB:SPCC794.11c; -.
DR eggNOG; KOG2056; Eukaryota.
DR HOGENOM; CLU_040577_0_1_1; -.
DR InParanoid; P78813; -.
DR OMA; WGPTSKQ; -.
DR PhylomeDB; P78813; -.
DR Reactome; R-SPO-8856825; Cargo recognition for clathrin-mediated endocytosis.
DR PRO; PR:P78813; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0030479; C:actin cortical patch; ISO:PomBase.
DR GO; GO:0030125; C:clathrin vesicle coat; ISO:PomBase.
DR GO; GO:0005829; C:cytosol; IEA:GOC.
DR GO; GO:0005768; C:endosome; IBA:GO_Central.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0005802; C:trans-Golgi network; EXP:PomBase.
DR GO; GO:0030276; F:clathrin binding; IBA:GO_Central.
DR GO; GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; ISM:PomBase.
DR GO; GO:0005543; F:phospholipid binding; IBA:GO_Central.
DR GO; GO:0000147; P:actin cortical patch assembly; ISO:PomBase.
DR GO; GO:0006897; P:endocytosis; ISO:PomBase.
DR GO; GO:0099638; P:endosome to plasma membrane protein transport; IMP:PomBase.
DR GO; GO:0006895; P:Golgi to endosome transport; IMP:PomBase.
DR GO; GO:0042147; P:retrograde transport, endosome to Golgi; IMP:PomBase.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR013809; ENTH.
DR InterPro; IPR008942; ENTH_VHS.
DR Pfam; PF01417; ENTH; 1.
DR SMART; SM00273; ENTH; 1.
DR SUPFAM; SSF48464; SSF48464; 1.
DR PROSITE; PS50942; ENTH; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..476
FT /note="ENTH domain-containing protein C794.11c"
FT /id="PRO_0000116555"
FT DOMAIN 30..154
FT /note="ENTH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00243"
FT REGION 157..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 213..308
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 410..429
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 444..472
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 175..196
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 243..257
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 173
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 228
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 235
FT /note="Phosphotyrosine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 243
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 244
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
FT MOD_RES 459
FT /note="Phosphoserine"
FT /evidence="ECO:0000269|PubMed:18257517"
SQ SEQUENCE 476 AA; 51751 MW; 605C8DA347BB56D6 CRC64;
MESIQSTMKN INLYDIKAAV RKAQNVVMNY TSMEARVREA TNNEPWGAST SLMMEIAQGT
HNYSQLNEIL PMIYRRFTEK TAEEWRQIYK ALQLLEFLVK NGSERVVDDA RAHQATIKML
RNFHYIDHRQ KDQGLNVRTR AKELVELLND SERIRKERKR ARQNRGKFIG VGSDGDSRIS
TSSKSRFPSF GSSRGSYRTR VYGDGGGFTD YGNGYHDSSS MSDSRDASDN DVEEYNEDGD
GGSSDAATAN STRGSRRTTT KQSDKAPEQP KQESAMIDLL GLDNEPSPAQ PQTNTSAPLA
FEDDGFGDFQ SSAAAPASST LNNASLFMGS QTASTAAKND DDAFDDFQSA PSAKPASNTA
AFSSISFGGF NSLNQLPTSS SAFTPQPTTF NTGYTSAFGM SSGLSNTSSQ AGLGLTSQQP
TAAKSSGSNG DAFGSLWSSA VNKVHQENST RERVVSSSSE PVSKTQNFLD NDNLLL
