YCUA_SCHPO
ID YCUA_SCHPO Reviewed; 525 AA.
AC O59830;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 25-MAY-2022, entry version 117.
DE RecName: Full=Uncharacterized transcriptional regulatory protein C965.10;
GN ORFNames=SPCC965.10;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC {ECO:0000255|PROSITE-ProRule:PRU00227, ECO:0000269|PubMed:16823372}.
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DR EMBL; CU329672; CAA19070.1; -; Genomic_DNA.
DR PIR; T41663; T41663.
DR RefSeq; NP_588520.1; NM_001023509.2.
DR AlphaFoldDB; O59830; -.
DR SMR; O59830; -.
DR BioGRID; 275963; 3.
DR STRING; 4896.SPCC965.10.1; -.
DR MaxQB; O59830; -.
DR PaxDb; O59830; -.
DR EnsemblFungi; SPCC965.10.1; SPCC965.10.1:pep; SPCC965.10.
DR GeneID; 2539398; -.
DR KEGG; spo:SPCC965.10; -.
DR PomBase; SPCC965.10; -.
DR VEuPathDB; FungiDB:SPCC965.10; -.
DR eggNOG; ENOG502RIXM; Eukaryota.
DR HOGENOM; CLU_500636_0_0_1; -.
DR InParanoid; O59830; -.
DR OMA; FQGCIQP; -.
DR PhylomeDB; O59830; -.
DR PRO; PR:O59830; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; NAS:PomBase.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; ISM:PomBase.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; ISM:PomBase.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd00067; GAL4; 1.
DR Gene3D; 4.10.240.10; -; 1.
DR InterPro; IPR021858; Fun_TF.
DR InterPro; IPR001138; Zn2-C6_fun-type_DNA-bd.
DR InterPro; IPR036864; Zn2-C6_fun-type_DNA-bd_sf.
DR Pfam; PF11951; Fungal_trans_2; 1.
DR Pfam; PF00172; Zn_clus; 1.
DR SMART; SM00066; GAL4; 1.
DR SUPFAM; SSF57701; SSF57701; 1.
DR PROSITE; PS00463; ZN2_CY6_FUNGAL_1; 1.
DR PROSITE; PS50048; ZN2_CY6_FUNGAL_2; 1.
PE 3: Inferred from homology;
KW Cytoplasm; DNA-binding; Metal-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation; Zinc.
FT CHAIN 1..525
FT /note="Uncharacterized transcriptional regulatory protein
FT C965.10"
FT /id="PRO_0000310378"
FT DNA_BIND 21..48
FT /note="Zn(2)-C6 fungal-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00227"
SQ SEQUENCE 525 AA; 59800 MW; 5A2508FD0DBA090F CRC64;
MTSTSHFVAS TVKKPRSRYG CLICRSMRKK CDEVHPQCGR CLKAGKQCIW KQPGTERKNK
TKWRKAMQNN SIPIQDLADD FELDFPDTLD LTNPDALPVL GESIVNPISL PVDVASPFLP
SECYPSKVEL PYFPLLSKPN TLLSLLNDEE ISCCEYYCYS VAPITTILPG QPNFLPQLLL
PMALHEESVL YSLVASGYRL KYGNDNSLAL QKSKVFVNRA LLTLPERRSL NLSKSEFVVS
LACYILLVYT EIAFADTTEW ATYFLNAYNM INKMGGFKIL KECSSEGKLL AECFAYFDIL
ASQSNLNGTY YSISDYTDVY GVDELQLFES LENCIKPLVL IIGDIINLLV ESRRAGFDDL
QHTLNIYEKS QTIEGKIWSC VPQYEDMKSN KLDSEKSEPL QLFKLYKTTT EMYLRQVISR
MPPVSLEMQV LLHKQTQLID LLLESSLRNS LSFPMLIAGL NAATDLQRTN FKNRVNCLCQ
NYTIGSLKKV WIVVQEIWKM NQNGNICIDW YEVVQKFGWR LNTGV