YCUB_SCHPO
ID YCUB_SCHPO Reviewed; 537 AA.
AC O59831;
DT 14-AUG-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 25-MAY-2022, entry version 128.
DE RecName: Full=Uncharacterized amino-acid permease C965.11c;
GN ORFNames=SPCC965.11c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the amino acid-polyamine-organocation (APC)
CC superfamily. {ECO:0000305}.
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DR EMBL; CU329672; CAA19071.1; -; Genomic_DNA.
DR PIR; T41664; T41664.
DR RefSeq; NP_588521.1; NM_001023510.2.
DR AlphaFoldDB; O59831; -.
DR SMR; O59831; -.
DR BioGRID; 275744; 2.
DR STRING; 4896.SPCC965.11c.1; -.
DR PaxDb; O59831; -.
DR EnsemblFungi; SPCC965.11c.1; SPCC965.11c.1:pep; SPCC965.11c.
DR GeneID; 2539173; -.
DR KEGG; spo:SPCC965.11c; -.
DR PomBase; SPCC965.11c; -.
DR VEuPathDB; FungiDB:SPCC965.11c; -.
DR eggNOG; KOG1286; Eukaryota.
DR HOGENOM; CLU_007946_12_2_1; -.
DR InParanoid; O59831; -.
DR OMA; KGIANSF; -.
DR PhylomeDB; O59831; -.
DR PRO; PR:O59831; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:0015171; F:amino acid transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015190; F:L-leucine transmembrane transporter activity; IMP:PomBase.
DR GO; GO:0003333; P:amino acid transmembrane transport; IBA:GO_Central.
DR GO; GO:0098713; P:leucine import across plasma membrane; IMP:PomBase.
DR InterPro; IPR004841; AA-permease/SLC12A_dom.
DR Pfam; PF00324; AA_permease; 1.
PE 3: Inferred from homology;
KW Amino-acid transport; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..537
FT /note="Uncharacterized amino-acid permease C965.11c"
FT /id="PRO_0000054178"
FT TRANSMEM 52..72
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 76..96
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 183..203
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 219..239
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 267..287
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 318..338
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 362..382
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 393..413
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 462..482
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 537 AA; 59431 MW; C6022537E9AEE1CF CRC64;
MEAAPSEKVP AKKLSSSENL DIGVSEVVTV DAAENNSNGI KRGLKTRHVS MMALAGIIGP
GVFIGMGSAL HIGGPVGLIV GFAIVSIVVF GVMLSIGEFN SLFDFNFNTH AARWVDPAFG
AAIGWNYVIV WLTNIAAEYT SLTSILQYWG PHVPSYGFFL IFWGFFTCYQ MLGVSVFGES
EYILAFIKLL FITGFYIFAI IYAAGGIPHH KPPNLFKEMP LAHGFGGIVS AFVYAGVFFS
GVESVSMTAA ESKNPKKAIP LAVRQTFWRI LYVYFGISIS YGITVAWNDP NLSSGSKTLK
SPMTIAIMNA GWNHAGDFVN AVILITCLSS INSGIYIGSR SLYNLAKDGM APKIFKRVDK
RGVPWVAVHS VHLFGFLSIM NYSTGAVKAY GYIINLAGVS AFIVWTAIIF VHFRFRRGWV
KQGYALSDLP FKSPLYPFPQ LIGFVIGIIL TLVQGWTVFK PFAAGDFVDA YILLPLFFVI
WLSYKFIKKT KWVSYEDMDF INGRRVIEPT YSNEQSSDKE TEDGKKTSFW NRVWKEV
