YCUD_SCHPO
ID YCUD_SCHPO Reviewed; 537 AA.
AC O59833;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-AUG-1998, sequence version 1.
DT 25-MAY-2022, entry version 121.
DE RecName: Full=Uncharacterized transporter C965.13;
GN ORFNames=SPCC965.13;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1] {ECO:0000312|EMBL:CAA19073.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2] {ECO:0000305}
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum
CC {ECO:0000269|PubMed:16823372}. Golgi apparatus
CC {ECO:0000269|PubMed:16823372}. Membrane {ECO:0000255}; Multi-pass
CC membrane protein {ECO:0000255}. Note=Barrier septum. Cell tip.
CC {ECO:0000255, ECO:0000269|PubMed:16823372}.
CC -!- SIMILARITY: Belongs to the major facilitator superfamily. CAR1 family.
CC {ECO:0000255}.
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DR EMBL; CU329672; CAA19073.1; -; Genomic_DNA.
DR PIR; T41666; T41666.
DR RefSeq; NP_588523.1; NM_001023512.2.
DR AlphaFoldDB; O59833; -.
DR BioGRID; 275536; 21.
DR STRING; 4896.SPCC965.13.1; -.
DR iPTMnet; O59833; -.
DR SwissPalm; O59833; -.
DR MaxQB; O59833; -.
DR PaxDb; O59833; -.
DR EnsemblFungi; SPCC965.13.1; SPCC965.13.1:pep; SPCC965.13.
DR GeneID; 2538962; -.
DR KEGG; spo:SPCC965.13; -.
DR PomBase; SPCC965.13; -.
DR VEuPathDB; FungiDB:SPCC965.13; -.
DR eggNOG; KOG0255; Eukaryota.
DR HOGENOM; CLU_008455_11_5_1; -.
DR InParanoid; O59833; -.
DR OMA; WFAFTSS; -.
DR PhylomeDB; O59833; -.
DR PRO; PR:O59833; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0032153; C:cell division site; HDA:PomBase.
DR GO; GO:0051286; C:cell tip; HDA:PomBase.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0005887; C:integral component of plasma membrane; ISS:PomBase.
DR GO; GO:0031925; F:pyridoxal transmembrane transporter activity; ISS:PomBase.
DR GO; GO:0031927; F:pyridoxamine transmembrane transporter activity; ISS:PomBase.
DR GO; GO:0031928; F:pyridoxine transmembrane transporter activity; ISS:PomBase.
DR GO; GO:0022857; F:transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:1903090; P:pyridoxal transmembrane transport; ISS:PomBase.
DR GO; GO:1903091; P:pyridoxamine transmembrane transport; ISS:PomBase.
DR GO; GO:1903092; P:pyridoxine transmembrane transport; ISS:PomBase.
DR GO; GO:0055085; P:transmembrane transport; IBA:GO_Central.
DR Gene3D; 1.20.1250.20; -; 1.
DR InterPro; IPR011701; MFS.
DR InterPro; IPR020846; MFS_dom.
DR InterPro; IPR036259; MFS_trans_sf.
DR InterPro; IPR005829; Sugar_transporter_CS.
DR Pfam; PF07690; MFS_1; 1.
DR SUPFAM; SSF103473; SSF103473; 1.
DR PROSITE; PS50850; MFS; 1.
DR PROSITE; PS00216; SUGAR_TRANSPORT_1; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum; Golgi apparatus; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..537
FT /note="Uncharacterized transporter C965.13"
FT /id="PRO_0000372788"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 133..153
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 156..176
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 180..200
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 213..233
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 243..263
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 313..333
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 348..368
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 393..413
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 422..442
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 457..477
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 492..512
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 10..56
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 34..51
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 537 AA; 59707 MW; 31056DEDA6D1A7A6 CRC64;
MSILNVIRSH HDVEPQNVEE EPPLTGQTIV TEDKLETSAK DKKHESPSMS EDEEGSVENV
DAWDLTKALM SIDPNHPAHP HKWPLWKKLF VATVYTFLEV YVIWSSTACI NFFDIYQTNW
HCSIQVSYLV QSLFIVGNAF GPMLLGPMSD IFGRKWVYVG SLILYIIFQI PQALAYNLPM
MAINSAIAGA FGSSALANVA SSMCDIFTPE TVGFGISLFV WGANAGASIG SPIGEALYDH
WRWFYWMNMI VGGFFVILCV LCPETLPVIN IMNYSSTTGE KTVQVSTLAK AKSAVVRTKF
VLSTAFKLLC TEPIIMALGL YNGFAYGLIF LYLDGLFPVF VDNYKMGYMG ANLTYLNFLV
GVTIVVMLQP IQNWLYRWDK RRHGGVARPE ARFLISLLTV WFFPAGLFWF AFTSDGRISW
VSPLIAGGVL GVGDPQLWLA MINYITDSYP SVAGSAIAAF TLPSFAIAAV LVHLGIIMFD
NMTTTWAMAT LAFISLSLVA TIYVIYFFGH LIRKHSRLAV TQQALQEAHD AKVLPEV
