ID   CB048_HUMAN             Reviewed;         159 AA.
AC   Q96LS8;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Putative uncharacterized protein C2orf48 {ECO:0000305};
GN   Name=C2orf48;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain;
RX   PubMed=14702039; DOI=10.1038/ng1285;
RA   Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA   Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA   Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA   Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA   Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA   Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA   Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA   Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA   Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA   Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA   Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA   Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA   Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA   Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA   Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA   Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA   Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA   Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA   Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA   Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA   Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA   Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA   Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA   Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA   Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA   Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA   Isogai T., Sugano S.;
RT   "Complete sequencing and characterization of 21,243 full-length human
RT   cDNAs.";
RL   Nat. Genet. 36:40-45(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain, Heart, and Lung;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- CAUTION: Product of a dubious gene prediction. {ECO:0000305}.
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DR   EMBL; AK057831; BAB71592.1; -; mRNA.
DR   EMBL; BC093999; AAH93999.1; -; mRNA.
DR   EMBL; BC094001; AAH94001.1; -; mRNA.
DR   RefSeq; NP_872432.1; NM_182626.3.
DR   AlphaFoldDB; Q96LS8; -.
DR   BioGRID; 131528; 45.
DR   IntAct; Q96LS8; 8.
DR   STRING; 9606.ENSP00000482286; -.
DR   iPTMnet; Q96LS8; -.
DR   PhosphoSitePlus; Q96LS8; -.
DR   BioMuta; HGNC:26322; -.
DR   DMDM; 74732249; -.
DR   PaxDb; Q96LS8; -.
DR   PRIDE; Q96LS8; -.
DR   neXtProt; NX_Q96LS8; -.
DR   eggNOG; ENOG502TDYA; Eukaryota.
DR   InParanoid; Q96LS8; -.
DR   OrthoDB; 1340747at2759; -.
DR   PhylomeDB; Q96LS8; -.
DR   PathwayCommons; Q96LS8; -.
DR   SignaLink; Q96LS8; -.
DR   BioGRID-ORCS; 348738; 10 hits in 1040 CRISPR screens.
DR   ChiTaRS; C2orf48; human.
DR   GenomeRNAi; 348738; -.
DR   Pharos; Q96LS8; Tdark.
DR   PRO; PR:Q96LS8; -.
DR   Proteomes; UP000005640; Unplaced.
DR   RNAct; Q96LS8; protein.
PE   5: Uncertain;
KW   Reference proteome.
FT   CHAIN           1..159
FT                   /note="Putative uncharacterized protein C2orf48"
FT                   /id="PRO_0000263748"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        12..29
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VARIANT         90
FT                   /note="P -> L (in dbSNP:rs13406078)"
FT                   /id="VAR_029619"
FT   VARIANT         119
FT                   /note="W -> S (in dbSNP:rs7423163)"
FT                   /id="VAR_050713"
SQ   SEQUENCE   159 AA;  17367 MW;  685BAEC54E451FA3 CRC64;
     MESRPSGRQH ASEGDGDQSP TQCAGMRSSG RSDQPYVLKG NPLLLRVRCY SGCASGSGRQ
     LQLSVFQDLN QFSHCRVWRS PALIVKGEPP WCSQQDTQSP FQTGTPLERP CFRMKLSGWE
     LTKNAQRALG SKLQHILSLD STQACGAGGP TILRPPRAP