ID   CB050_HUMAN             Reviewed;         162 AA.
AC   Q96LR7; A8K9W3; D6W503;
DT   23-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Uncharacterized protein C2orf50;
GN   Name=C2orf50;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain, and Trachea;
RX   PubMed=14702039; DOI=10.1038/ng1285;
RA   Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA   Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA   Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA   Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA   Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA   Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA   Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA   Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA   Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA   Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA   Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA   Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA   Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA   Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA   Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA   Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA   Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA   Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA   Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA   Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA   Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA   Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA   Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA   Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA   Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA   Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA   Isogai T., Sugano S.;
RT   "Complete sequencing and characterization of 21,243 full-length human
RT   cDNAs.";
RL   Nat. Genet. 36:40-45(2004).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Mural R.J., Istrail S., Sutton G.G., Florea L., Halpern A.L., Mobarry C.M.,
RA   Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA   Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA   Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA   Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA   Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA   Hunkapiller M.W., Myers E.W., Venter J.C.;
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- INTERACTION:
CC       Q96LR7; O15217: GSTA4; NbExp=6; IntAct=EBI-10290932, EBI-752440;
CC       Q96LR7; Q9UHY1: NRBP1; NbExp=3; IntAct=EBI-10290932, EBI-749731;
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DR   EMBL; AK057872; BAB71603.1; -; mRNA.
DR   EMBL; AK292828; BAF85517.1; -; mRNA.
DR   EMBL; CH471053; EAX00943.1; -; Genomic_DNA.
DR   EMBL; CH471053; EAX00944.1; -; Genomic_DNA.
DR   EMBL; BC120930; AAI20931.1; -; mRNA.
DR   CCDS; CCDS1678.1; -.
DR   RefSeq; NP_872306.1; NM_182500.2.
DR   RefSeq; XP_006711920.1; XM_006711857.2.
DR   RefSeq; XP_006711921.1; XM_006711858.2.
DR   RefSeq; XP_006711922.1; XM_006711859.3.
DR   AlphaFoldDB; Q96LR7; -.
DR   BioGRID; 126256; 11.
DR   IntAct; Q96LR7; 2.
DR   BioMuta; C2orf50; -.
DR   MassIVE; Q96LR7; -.
DR   PaxDb; Q96LR7; -.
DR   PeptideAtlas; Q96LR7; -.
DR   PRIDE; Q96LR7; -.
DR   ProteomicsDB; 77240; -.
DR   Antibodypedia; 58728; 60 antibodies from 9 providers.
DR   DNASU; 130813; -.
DR   Ensembl; ENST00000381585.8; ENSP00000370997.3; ENSG00000150873.12.
DR   Ensembl; ENST00000405022.3; ENSP00000384186.3; ENSG00000150873.12.
DR   GeneID; 130813; -.
DR   KEGG; hsa:130813; -.
DR   MANE-Select; ENST00000381585.8; ENSP00000370997.3; NM_001371321.1; NP_001358250.1.
DR   UCSC; uc010yji.1; human.
DR   CTD; 130813; -.
DR   GeneCards; C2orf50; -.
DR   HGNC; HGNC:26324; C2orf50.
DR   HPA; ENSG00000150873; Tissue enhanced (choroid plexus, fallopian tube).
DR   neXtProt; NX_Q96LR7; -.
DR   OpenTargets; ENSG00000150873; -.
DR   PharmGKB; PA162379180; -.
DR   VEuPathDB; HostDB:ENSG00000150873; -.
DR   eggNOG; ENOG502S2T8; Eukaryota.
DR   GeneTree; ENSGT00940000154459; -.
DR   HOGENOM; CLU_101818_0_0_1; -.
DR   InParanoid; Q96LR7; -.
DR   OMA; QRWAQNW; -.
DR   OrthoDB; 1456634at2759; -.
DR   PhylomeDB; Q96LR7; -.
DR   TreeFam; TF329466; -.
DR   PathwayCommons; Q96LR7; -.
DR   SignaLink; Q96LR7; -.
DR   BioGRID-ORCS; 130813; 14 hits in 1033 CRISPR screens.
DR   GenomeRNAi; 130813; -.
DR   Pharos; Q96LR7; Tdark.
DR   PRO; PR:Q96LR7; -.
DR   Proteomes; UP000005640; Chromosome 2.
DR   RNAct; Q96LR7; protein.
DR   Bgee; ENSG00000150873; Expressed in right uterine tube and 64 other tissues.
DR   Genevisible; Q96LR7; HS.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..162
FT                   /note="Uncharacterized protein C2orf50"
FT                   /id="PRO_0000307802"
FT   REGION          1..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..17
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   162 AA;  17838 MW;  51E319A606889CF6 CRC64;
     MGSHPTPGLQ RTTSAGYRLP PTRPPASVSP AARGGPMASR GLAGGCQAPQ ALKAQRVAQG
     AACDGVQQDQ LWRELLEAER RGQQRWIQNW SFLKDYDPMG NKKEPEKLPD HVPLFSDTVP
     SSTNQVVGSR LDTPLGQTLI RMDFFFTEGA RKKKLEDQMQ PI