YCY0_YEAST
ID YCY0_YEAST Reviewed; 182 AA.
AC P25654; D6VR90;
DT 01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-1992, sequence version 1.
DT 03-AUG-2022, entry version 133.
DE RecName: Full=UPF0587 protein YCR090C;
GN OrderedLocusNames=YCR090C; ORFNames=YCR1104, YCR90C;
OS Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=559292;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=1523889; DOI=10.1002/yea.320080708;
RA Wilson C., Grisanti P., Frontali L.;
RT "The complete sequence of a 6146 bp fragment of Saccharomyces cerevisiae
RT chromosome III contains two new open reading frames.";
RL Yeast 8:569-575(1992).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=1574125; DOI=10.1038/357038a0;
RA Oliver S.G., van der Aart Q.J.M., Agostoni-Carbone M.L., Aigle M.,
RA Alberghina L., Alexandraki D., Antoine G., Anwar R., Ballesta J.P.G.,
RA Benit P., Berben G., Bergantino E., Biteau N., Bolle P.-A.,
RA Bolotin-Fukuhara M., Brown A., Brown A.J.P., Buhler J.-M., Carcano C.,
RA Carignani G., Cederberg H., Chanet R., Contreras R., Crouzet M.,
RA Daignan-Fornier B., Defoor E., Delgado M.D., Demolder J., Doira C.,
RA Dubois E., Dujon B., Duesterhoeft A., Erdmann D., Esteban M., Fabre F.,
RA Fairhead C., Faye G., Feldmann H., Fiers W., Francingues-Gaillard M.-C.,
RA Franco L., Frontali L., Fukuhara H., Fuller L.J., Galland P., Gent M.E.,
RA Gigot D., Gilliquet V., Glansdorff N., Goffeau A., Grenson M., Grisanti P.,
RA Grivell L.A., de Haan M., Haasemann M., Hatat D., Hoenicka J.,
RA Hegemann J.H., Herbert C.J., Hilger F., Hohmann S., Hollenberg C.P.,
RA Huse K., Iborra F., Indge K.J., Isono K., Jacq C., Jacquet M., James C.M.,
RA Jauniaux J.-C., Jia Y., Jimenez A., Kelly A., Kleinhans U., Kreisl P.,
RA Lanfranchi G., Lewis C., van der Linden C.G., Lucchini G.,
RA Lutzenkirchen K., Maat M.J., Mallet L., Mannhaupt G., Martegani E.,
RA Mathieu A., Maurer C.T.C., McConnell D., McKee R.A., Messenguy F.,
RA Mewes H.-W., Molemans F., Montague M.A., Muzi Falconi M., Navas L.,
RA Newlon C.S., Noone D., Pallier C., Panzeri L., Pearson B.M., Perea J.,
RA Philippsen P., Pierard A., Planta R.J., Plevani P., Poetsch B., Pohl F.M.,
RA Purnelle B., Ramezani Rad M., Rasmussen S.W., Raynal A., Remacha M.A.,
RA Richterich P., Roberts A.B., Rodriguez F., Sanz E.,
RA Schaaff-Gerstenschlaeger I., Scherens B., Schweitzer B., Shu Y., Skala J.,
RA Slonimski P.P., Sor F., Soustelle C., Spiegelberg R., Stateva L.I.,
RA Steensma H.Y., Steiner S., Thierry A., Thireos G., Tzermia M.,
RA Urrestarazu L.A., Valle G., Vetter I., van Vliet-Reedijk J.C., Voet M.,
RA Volckaert G., Vreken P., Wang H., Warmington J.R., von Wettstein D.,
RA Wicksteed B.L., Wilson C., Wurst H., Xu G., Yoshikawa A., Zimmermann F.K.,
RA Sgouros J.G.;
RT "The complete DNA sequence of yeast chromosome III.";
RL Nature 357:38-46(1992).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=24374639; DOI=10.1534/g3.113.008995;
RA Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL G3 (Bethesda) 4:389-398(2014).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 204508 / S288c;
RX PubMed=17322287; DOI=10.1101/gr.6037607;
RA Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA LaBaer J.;
RT "Approaching a complete repository of sequence-verified protein-encoding
RT clones for Saccharomyces cerevisiae.";
RL Genome Res. 17:536-543(2007).
RN [5]
RP LEVEL OF PROTEIN EXPRESSION [LARGE SCALE ANALYSIS].
RX PubMed=14562106; DOI=10.1038/nature02046;
RA Ghaemmaghami S., Huh W.-K., Bower K., Howson R.W., Belle A., Dephoure N.,
RA O'Shea E.K., Weissman J.S.;
RT "Global analysis of protein expression in yeast.";
RL Nature 425:737-741(2003).
CC -!- DOMAIN: Requires a bound zinc ion for normal folding and solubility.
CC {ECO:0000250|UniProtKB:Q9NWV4}.
CC -!- MISCELLANEOUS: Present with 3970 molecules/cell in log phase SD medium.
CC {ECO:0000269|PubMed:14562106}.
CC -!- SIMILARITY: Belongs to the UPF0587 family. {ECO:0000305}.
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DR EMBL; X59720; CAA42255.1; -; Genomic_DNA.
DR EMBL; AY558154; AAS56480.1; -; Genomic_DNA.
DR EMBL; BK006937; DAA07559.1; -; Genomic_DNA.
DR PIR; S19506; S19506.
DR RefSeq; NP_010014.1; NM_001178796.1.
DR AlphaFoldDB; P25654; -.
DR SMR; P25654; -.
DR BioGRID; 31062; 258.
DR MINT; P25654; -.
DR STRING; 4932.YCR090C; -.
DR MaxQB; P25654; -.
DR PaxDb; P25654; -.
DR PRIDE; P25654; -.
DR EnsemblFungi; YCR090C_mRNA; YCR090C; YCR090C.
DR GeneID; 850452; -.
DR KEGG; sce:YCR090C; -.
DR SGD; S000000686; YCR090C.
DR VEuPathDB; FungiDB:YCR090C; -.
DR eggNOG; KOG1296; Eukaryota.
DR GeneTree; ENSGT00390000001523; -.
DR HOGENOM; CLU_114688_0_0_1; -.
DR InParanoid; P25654; -.
DR OMA; FFMKCKM; -.
DR BioCyc; YEAST:G3O-29384-MON; -.
DR PRO; PR:P25654; -.
DR Proteomes; UP000002311; Chromosome III.
DR RNAct; P25654; protein.
DR GO; GO:0005737; C:cytoplasm; HDA:SGD.
DR GO; GO:0005634; C:nucleus; HDA:SGD.
DR GO; GO:0008270; F:zinc ion binding; IBA:GO_Central.
DR InterPro; IPR008584; CXXC_Zn-binding_euk.
DR PANTHER; PTHR12857; PTHR12857; 1.
DR Pfam; PF05907; DUF866; 1.
PE 1: Evidence at protein level;
KW Metal-binding; Reference proteome; Zinc.
FT CHAIN 1..182
FT /note="UPF0587 protein YCR090C"
FT /id="PRO_0000202580"
FT BINDING 36
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:Q9NWV4"
FT BINDING 39
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:Q9NWV4"
FT BINDING 70
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:Q9NWV4"
FT BINDING 73
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000250|UniProtKB:Q9NWV4"
SQ SEQUENCE 182 AA; 20704 MW; BF03D05179E74483 CRC64;
MPLFLVLKAT LSENVTKVSI ENTNESRAEF AFDLQCTSCR ELHDSKVIIN TFEEYAMPAS
KGTASFLMKC KFCSKELSVN LCAFEDEYLT DQSDDKWAKI KDVRKKHGLS KVKEDSFIPL
SLDCRGCELI KFYPDTITFE VSLSSGKVMS CQLEDNEWYD YDDNLGEEVT MTDFSSSIIK
GK
