YCY3_SCHPO
ID YCY3_SCHPO Reviewed; 502 AA.
AC O74840; P78823;
DT 29-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT 11-JUL-2012, sequence version 2.
DT 25-MAY-2022, entry version 108.
DE RecName: Full=Smr domain-containing protein C1235.03;
GN ORFNames=SPCC1235.03;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
RN [2]
RP REVISION OF GENE MODEL.
RX PubMed=21511999; DOI=10.1126/science.1203357;
RA Rhind N., Chen Z., Yassour M., Thompson D.A., Haas B.J., Habib N.,
RA Wapinski I., Roy S., Lin M.F., Heiman D.I., Young S.K., Furuya K., Guo Y.,
RA Pidoux A., Chen H.M., Robbertse B., Goldberg J.M., Aoki K., Bayne E.H.,
RA Berlin A.M., Desjardins C.A., Dobbs E., Dukaj L., Fan L., FitzGerald M.G.,
RA French C., Gujja S., Hansen K., Keifenheim D., Levin J.Z., Mosher R.A.,
RA Mueller C.A., Pfiffner J., Priest M., Russ C., Smialowska A., Swoboda P.,
RA Sykes S.M., Vaughn M., Vengrova S., Yoder R., Zeng Q., Allshire R.,
RA Baulcombe D., Birren B.W., Brown W., Ekwall K., Kellis M., Leatherwood J.,
RA Levin H., Margalit H., Martienssen R., Nieduszynski C.A., Spatafora J.W.,
RA Friedman N., Dalgaard J.Z., Baumann P., Niki H., Regev A., Nusbaum C.;
RT "Comparative functional genomics of the fission yeasts.";
RL Science 332:930-936(2011).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 181-502.
RC STRAIN=PR745;
RX PubMed=9501991; DOI=10.1093/dnares/4.6.363;
RA Yoshioka S., Kato K., Nakai K., Okayama H., Nojima H.;
RT "Identification of open reading frames in Schizosaccharomyces pombe
RT cDNAs.";
RL DNA Res. 4:363-369(1997).
RN [4]
RP SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX PubMed=16823372; DOI=10.1038/nbt1222;
RA Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA Yoshida M.;
RT "ORFeome cloning and global analysis of protein localization in the fission
RT yeast Schizosaccharomyces pombe.";
RL Nat. Biotechnol. 24:841-847(2006).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000269|PubMed:16823372}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAA13833.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; CU329672; CAA21107.2; -; Genomic_DNA.
DR EMBL; D89171; BAA13833.1; ALT_FRAME; mRNA.
DR PIR; T40877; T40877.
DR PIR; T42536; T42536.
DR RefSeq; NP_587729.2; NM_001022724.2.
DR AlphaFoldDB; O74840; -.
DR SMR; O74840; -.
DR BioGRID; 275864; 9.
DR STRING; 4896.SPCC1235.03.1; -.
DR MaxQB; O74840; -.
DR PaxDb; O74840; -.
DR EnsemblFungi; SPCC1235.03.1; SPCC1235.03.1:pep; SPCC1235.03.
DR GeneID; 2539296; -.
DR KEGG; spo:SPCC1235.03; -.
DR PomBase; SPCC1235.03; -.
DR VEuPathDB; FungiDB:SPCC1235.03; -.
DR eggNOG; KOG2401; Eukaryota.
DR HOGENOM; CLU_543104_0_0_1; -.
DR InParanoid; O74840; -.
DR OMA; WRVEVGE; -.
DR PRO; PR:O74840; -.
DR Proteomes; UP000002485; Chromosome III.
DR GO; GO:0005737; C:cytoplasm; IC:PomBase.
DR GO; GO:0005730; C:nucleolus; HDA:PomBase.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0004519; F:endonuclease activity; ISO:PomBase.
DR GO; GO:0043130; F:ubiquitin binding; ISO:PomBase.
DR GO; GO:0070966; P:nuclear-transcribed mRNA catabolic process, no-go decay; ISO:PomBase.
DR Gene3D; 3.30.1370.110; -; 1.
DR InterPro; IPR002625; Smr_dom.
DR InterPro; IPR036063; Smr_dom_sf.
DR Pfam; PF01713; Smr; 1.
DR SMART; SM00463; SMR; 1.
DR SUPFAM; SSF160443; SSF160443; 1.
DR PROSITE; PS50828; SMR; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome.
FT CHAIN 1..502
FT /note="Smr domain-containing protein C1235.03"
FT /id="PRO_0000116560"
FT DOMAIN 411..459
FT /note="Smr"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00321"
FT REGION 150..184
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..172
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 322
FT /note="T -> I (in Ref. 3; BAA13833)"
FT /evidence="ECO:0000305"
FT CONFLICT 428
FT /note="E -> G (in Ref. 3; BAA13833)"
FT /evidence="ECO:0000305"
FT CONFLICT 485
FT /note="G -> S (in Ref. 3; BAA13833)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 502 AA; 57496 MW; 002ED5188E555F5D CRC64;
MQDWRAALEE YYSRYLDSAL VLAIVNDSDD SNTAREILEA LSIESQCDSH EEHWDNLRRD
EQELLNLKTL DEEINKIDEE DFTWELKDSS LELDPDVYNF LRSMFSDLSA ARVQLVQAKC
QNDLVRSSDE LLNHRAIQES EQIETAADAL ITSNIGHRSR QRKKKTKKAT NSRKPLSKFQ
SNTEEVNEDP ILKPSLSVWE NNRLLIEKLT SILNIPSSQI NHEFYKNSSA WPITIRNLIH
RHQPLSNITN NELMKYQEEA TQLAKDTGLS LKICTDVLIC SNDYKNALWI LCLIKETQHN
EMGNIKLSSQ TAKSNSSTQT KTCLNDQSSK LVEDDEALSA EDCNRLAEEY LELRNMQYSN
SAKEYRRSKS NHLFGGSAMY HAQLGREYHE KALKYRSLAM RSLAHSGTSH SLDLHGATVR
EAKTIVRERV AAWWAKEADT SPNSIRPFVI VTGRGNHSIG LEARLLPAIV RLLQQDHWRF
DAEHGQITVY GINRHSKLNS NA
