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CB068_MOUSE
ID   CB068_MOUSE             Reviewed;         166 AA.
AC   Q149G0; Q9DCK6;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-AUG-2006, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=UPF0561 protein C2orf68 homolog;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Kidney;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Brain, and Mammary gland;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
CC   -!- SIMILARITY: Belongs to the UPF0561 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB22295.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; AK002701; BAB22295.1; ALT_FRAME; mRNA.
DR   EMBL; BC064080; AAH64080.1; -; mRNA.
DR   EMBL; BC066053; AAH66053.1; -; mRNA.
DR   EMBL; BC117812; AAI17813.1; -; mRNA.
DR   CCDS; CCDS51808.1; -.
DR   RefSeq; NP_080972.1; NM_026696.1.
DR   AlphaFoldDB; Q149G0; -.
DR   SMR; Q149G0; -.
DR   STRING; 10090.ENSMUSP00000076957; -.
DR   iPTMnet; Q149G0; -.
DR   PhosphoSitePlus; Q149G0; -.
DR   EPD; Q149G0; -.
DR   MaxQB; Q149G0; -.
DR   PaxDb; Q149G0; -.
DR   PRIDE; Q149G0; -.
DR   Antibodypedia; 31940; 42 antibodies from 12 providers.
DR   Ensembl; ENSMUST00000077783; ENSMUSP00000076957; ENSMUSG00000058706.
DR   GeneID; 68364; -.
DR   KEGG; mmu:68364; -.
DR   UCSC; uc009cig.2; mouse.
DR   MGI; MGI:1915614; 0610030E20Rik.
DR   VEuPathDB; HostDB:ENSMUSG00000058706; -.
DR   eggNOG; ENOG502S396; Eukaryota.
DR   GeneTree; ENSGT00390000001901; -.
DR   HOGENOM; CLU_100251_0_0_1; -.
DR   InParanoid; Q149G0; -.
DR   OMA; PVNPDCE; -.
DR   OrthoDB; 1627419at2759; -.
DR   PhylomeDB; Q149G0; -.
DR   TreeFam; TF328804; -.
DR   BioGRID-ORCS; 68364; 2 hits in 72 CRISPR screens.
DR   PRO; PR:Q149G0; -.
DR   Proteomes; UP000000589; Chromosome 6.
DR   RNAct; Q149G0; protein.
DR   Bgee; ENSMUSG00000058706; Expressed in granulocyte and 62 other tissues.
DR   Genevisible; Q149G0; MM.
DR   InterPro; IPR018888; UPF0561.
DR   PANTHER; PTHR34256; PTHR34256; 1.
DR   Pfam; PF10573; UPF0561; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..166
FT                   /note="UPF0561 protein C2orf68 homolog"
FT                   /id="PRO_0000328786"
FT   REGION          32..107
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        32..46
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        67..82
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        85..101
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   166 AA;  18643 MW;  22CB2CD9E6D97DF7 CRC64;
     MEAAQDHGPG LCCKPGGRLD MSHGFVHHIR RNQLDRDDYD KKVKQAAKEK ARRRHTPAPT
     RPRKPDLQVY LPRHRDGSTH PVNPDCEEAS ESSSSGSSEL EPPGRQLFCL DYEADSGEVT
     SVIVYQDDDP GRVSEAVSAH TPLDPAMREA LRSRIQEELA KRQSRH
 
 
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