CB073_MOUSE
ID CB073_MOUSE Reviewed; 233 AA.
AC Q5SPV6; Q810N4; Q9D580;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 21-DEC-2004, sequence version 1.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Uncharacterized protein C2orf73 homolog;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q5SPV6-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q5SPV6-2; Sequence=VSP_033354;
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DR EMBL; AK015698; BAB29936.1; -; mRNA.
DR EMBL; AL844147; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR CCDS; CCDS48764.1; -. [Q5SPV6-1]
DR RefSeq; NP_001093864.1; NM_001100394.1. [Q5SPV6-1]
DR AlphaFoldDB; Q5SPV6; -.
DR BioGRID; 217209; 1.
DR STRING; 10090.ENSMUSP00000045288; -.
DR PhosphoSitePlus; Q5SPV6; -.
DR PaxDb; Q5SPV6; -.
DR PRIDE; Q5SPV6; -.
DR Antibodypedia; 66471; 10 antibodies from 6 providers.
DR Ensembl; ENSMUST00000041763; ENSMUSP00000045288; ENSMUSG00000040919. [Q5SPV6-1]
DR GeneID; 75087; -.
DR KEGG; mmu:75087; -.
DR UCSC; uc007ihv.1; mouse. [Q5SPV6-1]
DR MGI; MGI:1922337; 4930505A04Rik.
DR VEuPathDB; HostDB:ENSMUSG00000040919; -.
DR eggNOG; ENOG502S2FJ; Eukaryota.
DR GeneTree; ENSGT00390000005045; -.
DR HOGENOM; CLU_084649_0_0_1; -.
DR InParanoid; Q5SPV6; -.
DR OMA; PVKHSRM; -.
DR OrthoDB; 1586889at2759; -.
DR PhylomeDB; Q5SPV6; -.
DR TreeFam; TF337686; -.
DR BioGRID-ORCS; 75087; 1 hit in 74 CRISPR screens.
DR PRO; PR:Q5SPV6; -.
DR Proteomes; UP000000589; Chromosome 11.
DR RNAct; Q5SPV6; protein.
DR Bgee; ENSMUSG00000040919; Expressed in seminiferous tubule of testis and 28 other tissues.
DR ExpressionAtlas; Q5SPV6; baseline and differential.
DR Genevisible; Q5SPV6; MM.
DR InterPro; IPR031365; GDWWSH.
DR PANTHER; PTHR35087; PTHR35087; 1.
DR Pfam; PF15667; GDWWSH; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..233
FT /note="Uncharacterized protein C2orf73 homolog"
FT /id="PRO_0000332214"
FT REGION 1..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 192..233
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 194..233
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1..120
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16141072"
FT /id="VSP_033354"
SQ SEQUENCE 233 AA; 26410 MW; 95194743FFF67A33 CRC64;
MEGEEKQQQH KTEDDGIACV AERKVEIKNE KSPGKSTQHP KPCVDRRRVN YAKFIHTNAR
TYNEPVPYID NKGPEKQRKW WFHNEAPKHV SQPSYDTKSV QRSDFQKPAC PLVLPVKHSR
MQKPSCGIVP LTSLDVSGEH ENNFVEYISF IHQYDARRTP NEPIKGKKHG TFVQREIKLG
AMPIVPKAPE VLLNTLESGS SEQPQKTDKG NSSGDKVTSP GLCQQNSQEL LET
