CB078_MOUSE
ID CB078_MOUSE Reviewed; 857 AA.
AC Q3V0A6; B2RW58;
DT 26-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 11-OCT-2005, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Uncharacterized protein C2orf78 homolog;
GN Name=Gm5592;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Testis;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
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DR EMBL; AK133295; BAE21598.1; -; mRNA.
DR EMBL; BC147594; AAI47595.1; -; mRNA.
DR CCDS; CCDS52209.1; -.
DR RefSeq; NP_001028954.1; NM_001033782.3.
DR AlphaFoldDB; Q3V0A6; -.
DR STRING; 10090.ENSMUSP00000094809; -.
DR iPTMnet; Q3V0A6; -.
DR PhosphoSitePlus; Q3V0A6; -.
DR PaxDb; Q3V0A6; -.
DR PRIDE; Q3V0A6; -.
DR ProteomicsDB; 265558; -.
DR Ensembl; ENSMUST00000097044; ENSMUSP00000094809; ENSMUSG00000072259.
DR Ensembl; ENSMUST00000206490; ENSMUSP00000145899; ENSMUSG00000072259.
DR GeneID; 434172; -.
DR KEGG; mmu:434172; -.
DR UCSC; uc009glk.1; mouse.
DR MGI; MGI:3648691; Gm5592.
DR VEuPathDB; HostDB:ENSMUSG00000072259; -.
DR eggNOG; ENOG502SEP6; Eukaryota.
DR GeneTree; ENSGT00390000014208; -.
DR HOGENOM; CLU_016596_0_0_1; -.
DR InParanoid; Q3V0A6; -.
DR OMA; PRICHSM; -.
DR OrthoDB; 669317at2759; -.
DR PhylomeDB; Q3V0A6; -.
DR TreeFam; TF337929; -.
DR BioGRID-ORCS; 434172; 2 hits in 64 CRISPR screens.
DR ChiTaRS; Gm5592; mouse.
DR PRO; PR:Q3V0A6; -.
DR Proteomes; UP000000589; Chromosome 7.
DR RNAct; Q3V0A6; protein.
DR Bgee; ENSMUSG00000072259; Expressed in spermatocyte and 2 other tissues.
DR InterPro; IPR040292; C2orf78-like.
DR InterPro; IPR027898; DUF4629.
DR PANTHER; PTHR31466; PTHR31466; 1.
DR Pfam; PF15442; DUF4629; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..857
FT /note="Uncharacterized protein C2orf78 homolog"
FT /id="PRO_0000319423"
FT REGION 316..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 484..561
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 619..777
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 809..836
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 499..529
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..550
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 679..742
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 749..763
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 809..825
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 857 AA; 93729 MW; A450C4720D6F1284 CRC64;
MSENSQSSPF FGTESTLHPS LPLLSNSIQP AGTVCNFSRV STPDVSSAWL LPSASSTSLQ
PLMGNAYLNP HAGTTMLTVL TEQGQISTST PSYPGALKWD CTGSTHGRED ALQEFNMKLI
DQDTTLSSLA VTNQSDKILD PNVIVPFHPT LSSSFVQITP SQMPNQGYSL APSYQEGSQV
YYYEHNNLGP LIAGEFGQCL KAHGSVSYPG SQTSVLQPEM VMVLKEIQPR NIQMPLFTSA
FSYSTSAQSM PDNGLPVVQM ETSLGLPPSG QTHCQLQSPE LCNTCVQVSQ IRPPAVNGDK
ALTAPIHSPS EFLALPPAPS LEQPENKTMP EIKEGTKENQ DRPVLTLEHP DLQQPLHCTD
TESLRQKPDS DNAHLGCICM GPKELVGLEN ENGSSFNFKD ITRLEADIQL PQLLNTLTDI
DQDQSCETWT VTSGPSDQVR KNKHKSFELL EGAPQAKFQH WDLVEGEGAG GVAGASERAI
DNMAKQPEGK APKGPPSKNR KARKQEQERP SGPQNKSKKT EELKQSRNTA KAEENLSIPK
TKRKRNPPEL SQNSFKKPRT NLAMHMLESV QVFHPLGKKT EKKTGISSFR GLRTFTINKD
PGPGSGTVTT TVLNMPCEGQ FPPKSPGKVQ RAESSIDKDC LSPSQYELPP AGKVKLVPLP
FPTLDKPQSR PASRKPLSLA LRRTTTVQPH SHSAQPTTLR PAQPPPVSSS LIASAKPAPP
ISSSSTGPNV TNPNQSSAVP HLVTSRPVPY RASSHTSFQR ELVSAARNKV PSPPKPQTKY
LLHDFSRQPI PWKKVDILGP VVSQPITKEQ RPEREAMKRQ AQQERENAVK NPSTGKLQIF
LQRERDMEIS QYYGYAM
