YD68_SCHPO
ID YD68_SCHPO Reviewed; 287 AA.
AC Q10320;
DT 01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1996, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=GDT1-like protein C17G8.08c;
GN ORFNames=SPAC17G8.08c;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the GDT1 family. {ECO:0000305}.
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DR EMBL; CU329670; CAA93691.1; -; Genomic_DNA.
DR PIR; T37860; T37860.
DR RefSeq; NP_593731.1; NM_001019162.2.
DR AlphaFoldDB; Q10320; -.
DR BioGRID; 278683; 11.
DR STRING; 4896.SPAC17G8.08c.1; -.
DR TCDB; 2.A.106.2.4; the ca(2+):h(+) antiporter-2 (caca2) family.
DR iPTMnet; Q10320; -.
DR PaxDb; Q10320; -.
DR PRIDE; Q10320; -.
DR EnsemblFungi; SPAC17G8.08c.1; SPAC17G8.08c.1:pep; SPAC17G8.08c.
DR GeneID; 2542208; -.
DR KEGG; spo:SPAC17G8.08c; -.
DR PomBase; SPAC17G8.08c; -.
DR VEuPathDB; FungiDB:SPAC17G8.08c; -.
DR eggNOG; KOG2881; Eukaryota.
DR HOGENOM; CLU_040186_0_0_1; -.
DR InParanoid; Q10320; -.
DR OMA; QGKWHSF; -.
DR PhylomeDB; Q10320; -.
DR PRO; PR:Q10320; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005783; C:endoplasmic reticulum; HDA:PomBase.
DR GO; GO:0005794; C:Golgi apparatus; HDA:PomBase.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015085; F:calcium ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015369; F:calcium:proton antiporter activity; TAS:PomBase.
DR GO; GO:0005384; F:manganese ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0070588; P:calcium ion transmembrane transport; IBA:GO_Central.
DR GO; GO:0032468; P:Golgi calcium ion homeostasis; IBA:GO_Central.
DR GO; GO:0032472; P:Golgi calcium ion transport; IBA:GO_Central.
DR GO; GO:0071421; P:manganese ion transmembrane transport; IBA:GO_Central.
DR GO; GO:1902600; P:proton transmembrane transport; TAS:PomBase.
DR InterPro; IPR001727; Gdt1.
DR PANTHER; PTHR12608; PTHR12608; 1.
DR Pfam; PF01169; UPF0016; 2.
DR PROSITE; PS01214; UPF0016; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..287
FT /note="GDT1-like protein C17G8.08c"
FT /id="PRO_0000212468"
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 50..70
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 89..109
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 112..132
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 194..214
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 232..252
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 267..287
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 287 AA; 31302 MW; 49148BC233D62947 CRC64;
MKNPIKWAII AVLLSTVVAK KIVGEGMADV SAIKHPEEVH PTNRDFLRSL IFSISMIFGC
EIGDKTFIVA ALLAFENSRL TVFAGSYSAL FIMTLLGVLL GHAAPLLFPR KLTDILGGVL
FVIFGIKMLM EAKEVMDSKE SMSDEFQNVR NEIAANGPID QLLEEGAAPS HYTGHRSRSG
HTLMSQLKSK GRNVMATLFS PLFIKAFALT FVSEWGDRSQ IATIAMAASD NVYGVFMGAN
VGHACCTALA VISGKYISTK IKVHKVMFIG GILFIAFGLV YFYQGFF
