ID   YDA6_SCHPO              Reviewed;         252 AA.
AC   Q10348;
DT   01-OCT-1996, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1996, sequence version 1.
DT   03-AUG-2022, entry version 115.
DE   RecName: Full=Putative endonuclease C1F12.06c;
DE            EC=3.1.-.-;
GN   ORFNames=SPAC1F12.06c;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
RN   [2]
RP   SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS].
RX   PubMed=16823372; DOI=10.1038/nbt1222;
RA   Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S.,
RA   Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S.,
RA   Yoshida M.;
RT   "ORFeome cloning and global analysis of protein localization in the fission
RT   yeast Schizosaccharomyces pombe.";
RL   Nat. Biotechnol. 24:841-847(2006).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:16823372}. Nucleus
CC       {ECO:0000269|PubMed:16823372}.
CC   -!- SIMILARITY: Belongs to the endonuclease V family. {ECO:0000305}.
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DR   EMBL; CU329670; CAA93810.1; -; Genomic_DNA.
DR   PIR; T38064; S67449.
DR   RefSeq; NP_594332.1; NM_001019753.2.
DR   AlphaFoldDB; Q10348; -.
DR   SMR; Q10348; -.
DR   BioGRID; 278896; 2.
DR   STRING; 4896.SPAC1F12.06c.1; -.
DR   PaxDb; Q10348; -.
DR   PRIDE; Q10348; -.
DR   EnsemblFungi; SPAC1F12.06c.1; SPAC1F12.06c.1:pep; SPAC1F12.06c.
DR   GeneID; 2542434; -.
DR   KEGG; spo:SPAC1F12.06c; -.
DR   PomBase; SPAC1F12.06c; -.
DR   VEuPathDB; FungiDB:SPAC1F12.06c; -.
DR   eggNOG; KOG4417; Eukaryota.
DR   HOGENOM; CLU_047631_0_2_1; -.
DR   InParanoid; Q10348; -.
DR   OMA; RIHFRQA; -.
DR   PhylomeDB; Q10348; -.
DR   PRO; PR:Q10348; -.
DR   Proteomes; UP000002485; Chromosome I.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005829; C:cytosol; HDA:PomBase.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; HDA:PomBase.
DR   GO; GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; ISO:PomBase.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0003727; F:single-stranded RNA binding; IBA:GO_Central.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   GO; GO:0006397; P:mRNA processing; ISO:PomBase.
DR   CDD; cd06559; Endonuclease_V; 1.
DR   InterPro; IPR007581; Endonuclease-V.
DR   PANTHER; PTHR28511; PTHR28511; 1.
DR   Pfam; PF04493; Endonuclease_5; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Endonuclease; Hydrolase; Magnesium; Metal-binding; Nuclease;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..252
FT                   /note="Putative endonuclease C1F12.06c"
FT                   /id="PRO_0000159701"
FT   BINDING         43
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   BINDING         114
FT                   /ligand="Mg(2+)"
FT                   /ligand_id="ChEBI:CHEBI:18420"
FT                   /evidence="ECO:0000250"
FT   SITE            82
FT                   /note="Interaction with target DNA"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   252 AA;  28762 MW;  7DA5C029F7BF84B2 CRC64;
     MNNDNLHDKL TIWRQQQIEL KGMLQLIPKF QSLNEIRYVV GLDISFDKSS PKAVSALVIY
     DLEQRMIIYK DYLCIEKLEE DYVPGFLSFR EIKWYLPLLN HIPHQFRIDI ILVDGNGVLH
     PVGFGLACHL GVLLNLPVVG VAKNYLHCVG LTESLDAHRE TLKKHVLKKT TDHPILIHSI
     DQSSEILGAA VWTSSNSKRP VYVSIGNQMN LEQSIQLVQK CSSSHSRVPE PIRQADIYAK
     FVLSQSKRNK KN