YDCF_ECOLI
ID YDCF_ECOLI Reviewed; 266 AA.
AC P34209; P77578;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 3.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Protein YdcF;
GN Name=ydcF; OrderedLocusNames=b1414, JW1411;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12;
RA Hidalgo E., Limon A., Aguilar J.;
RT "A third gene with high homology to gap gene in the Escherichia coli
RT chromosome.";
RL Submitted (NOV-1993) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA Wada C., Yamamoto Y., Horiuchi T.;
RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 28.0-40.1 min region on the linkage map.";
RL DNA Res. 3:363-377(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY.
RC STRAIN=B / BL21;
RX PubMed=10493123;
RX DOI=10.1002/(sici)1522-2683(19990801)20:11<2181::aid-elps2181>3.0.co;2-q;
RA Fountoulakis M., Takacs M.-F., Berndt P., Langen H., Takacs B.;
RT "Enrichment of low abundance proteins of Escherichia coli by hydroxyapatite
RT chromatography.";
RL Electrophoresis 20:2181-2195(1999).
RN [6]
RP X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS), SUBUNIT, AND S-ADENOSYL-L-METHIONINE
RP BINDING.
RX PubMed=18393394; DOI=10.1002/prot.22046;
RA Chao K.L., Lim K., Lehmann C., Doseeva V., Howard A.J., Schwarz F.P.,
RA Herzberg O.;
RT "The Escherichia coli YdcF binds S-adenosyl-L-methionine and adopts an
RT alpha/beta-fold characteristic of nucleotide-utilizing enzymes.";
RL Proteins 72:506-509(2008).
CC -!- FUNCTION: Binds S-adenosyl-L-methionine (AdoMet).
CC -!- SUBUNIT: Monomer. {ECO:0000269|PubMed:18393394}.
CC -!- SIMILARITY: To S.coelicolor SCO4629. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA24246.1; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; L09068; AAA24246.1; ALT_FRAME; Genomic_DNA.
DR EMBL; U00096; AAC74496.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA15030.1; -; Genomic_DNA.
DR PIR; A64893; A64893.
DR RefSeq; NP_415932.1; NC_000913.3.
DR RefSeq; WP_001027942.1; NZ_SSZK01000021.1.
DR PDB; 3CA8; X-ray; 1.80 A; A/B=1-266.
DR PDBsum; 3CA8; -.
DR AlphaFoldDB; P34209; -.
DR SMR; P34209; -.
DR BioGRID; 4261553; 9.
DR BioGRID; 850575; 1.
DR DIP; DIP-11642N; -.
DR IntAct; P34209; 2.
DR STRING; 511145.b1414; -.
DR jPOST; P34209; -.
DR PaxDb; P34209; -.
DR PRIDE; P34209; -.
DR EnsemblBacteria; AAC74496; AAC74496; b1414.
DR EnsemblBacteria; BAA15030; BAA15030; BAA15030.
DR GeneID; 946215; -.
DR KEGG; ecj:JW1411; -.
DR KEGG; eco:b1414; -.
DR PATRIC; fig|1411691.4.peg.857; -.
DR EchoBASE; EB2033; -.
DR eggNOG; COG1434; Bacteria.
DR HOGENOM; CLU_084257_0_0_6; -.
DR InParanoid; P34209; -.
DR OMA; VIQDPTM; -.
DR PhylomeDB; P34209; -.
DR BioCyc; EcoCyc:EG12110-MON; -.
DR EvolutionaryTrace; P34209; -.
DR PRO; PR:P34209; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR CDD; cd06259; YdcF-like; 1.
DR Gene3D; 3.40.50.620; -; 1.
DR InterPro; IPR003848; DUF218.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR Pfam; PF02698; DUF218; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Reference proteome.
FT CHAIN 1..266
FT /note="Protein YdcF"
FT /id="PRO_0000168929"
FT CONFLICT 97
FT /note="A -> R (in Ref. 1; AAA24246)"
FT /evidence="ECO:0000305"
FT CONFLICT 217..266
FT /note="PRLRDDSDGYGPRGRDFIVHVDFPAEVIHAWQTLKHDAVLIEAMESRSLR
FT -> RVYAMIAMATVPAGEILSFTLIFRQKSSMHGKR (in Ref. 1)"
FT /evidence="ECO:0000305"
FT HELIX 11..25
FT /evidence="ECO:0007829|PDB:3CA8"
FT TURN 29..32
FT /evidence="ECO:0007829|PDB:3CA8"
FT STRAND 38..44
FT /evidence="ECO:0007829|PDB:3CA8"
FT HELIX 48..61
FT /evidence="ECO:0007829|PDB:3CA8"
FT STRAND 65..68
FT /evidence="ECO:0007829|PDB:3CA8"
FT HELIX 75..83
FT /evidence="ECO:0007829|PDB:3CA8"
FT HELIX 88..90
FT /evidence="ECO:0007829|PDB:3CA8"
FT HELIX 98..108
FT /evidence="ECO:0007829|PDB:3CA8"
FT HELIX 114..116
FT /evidence="ECO:0007829|PDB:3CA8"
FT STRAND 117..120
FT /evidence="ECO:0007829|PDB:3CA8"
FT HELIX 126..138
FT /evidence="ECO:0007829|PDB:3CA8"
FT STRAND 147..150
FT /evidence="ECO:0007829|PDB:3CA8"
FT TURN 153..155
FT /evidence="ECO:0007829|PDB:3CA8"
FT HELIX 156..167
FT /evidence="ECO:0007829|PDB:3CA8"
FT STRAND 175..178
FT /evidence="ECO:0007829|PDB:3CA8"
FT STRAND 186..189
FT /evidence="ECO:0007829|PDB:3CA8"
FT STRAND 192..197
FT /evidence="ECO:0007829|PDB:3CA8"
FT HELIX 205..219
FT /evidence="ECO:0007829|PDB:3CA8"
FT STRAND 225..227
FT /evidence="ECO:0007829|PDB:3CA8"
FT TURN 228..231
FT /evidence="ECO:0007829|PDB:3CA8"
FT HELIX 241..251
FT /evidence="ECO:0007829|PDB:3CA8"
FT HELIX 254..262
FT /evidence="ECO:0007829|PDB:3CA8"
SQ SEQUENCE 266 AA; 29706 MW; DA59CFB3D34728A5 CRC64;
MNITPFPTLS PATIDAINVI GQWLAQDDFS GEVPYQADCV ILAGNAVMPT IDAACKIARD
QQIPLLISGG IGHSTTFLYS AIAQHPHYNT IRTTGRAEAT ILADIAHQFW HIPHEKIWIE
DQSTNCGENA RFSIALLNQA VERVHTAIVV QDPTMQRRTM ATFRRMTGDN PDAPRWLSYP
GFVPQLGNNA DSVIFINQLQ GLWPVERYLS LLTGELPRLR DDSDGYGPRG RDFIVHVDFP
AEVIHAWQTL KHDAVLIEAM ESRSLR
