ID   CB092_HUMAN             Reviewed;         265 AA.
AC   A0A1B0GVN3;
DT   31-JAN-2018, integrated into UniProtKB/Swiss-Prot.
DT   05-OCT-2016, sequence version 1.
DT   03-AUG-2022, entry version 22.
DE   RecName: Full=Uncharacterized protein C2orf92 {ECO:0000305};
DE   AltName: Full=Long intergenic non-protein coding RNA 1125 {ECO:0000312|HGNC:HGNC:49272};
DE   Flags: Precursor;
GN   Name=C2orf92 {ECO:0000312|HGNC:HGNC:49272};
GN   Synonyms=LINC01125 {ECO:0000312|HGNC:HGNC:49272};
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=15815621; DOI=10.1038/nature03466;
RA   Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P.,
RA   Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C.,
RA   Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L.,
RA   Du H., Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A.,
RA   Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J.,
RA   Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M.,
RA   Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T.,
RA   Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S.,
RA   Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K.,
RA   McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C.,
RA   Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S.,
RA   Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C.,
RA   Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M.,
RA   Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C.,
RA   Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J.,
RA   Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E.,
RA   Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X.,
RA   Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M.,
RA   Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C.,
RA   Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S.,
RA   Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H.,
RA   Wilson R.K.;
RT   "Generation and annotation of the DNA sequences of human chromosomes 2 and
RT   4.";
RL   Nature 434:724-731(2005).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000255}; Single-pass membrane
CC       protein {ECO:0000255}.
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DR   EMBL; AC017099; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS86862.1; -.
DR   AlphaFoldDB; A0A1B0GVN3; -.
DR   SMR; A0A1B0GVN3; -.
DR   BioMuta; C2orf92; -.
DR   MassIVE; A0A1B0GVN3; -.
DR   Ensembl; ENST00000627399.4; ENSP00000490587.1; ENSG00000228486.11.
DR   MANE-Select; ENST00000627399.4; ENSP00000490587.1; NM_001351368.2; NP_001338297.1.
DR   GeneCards; C2orf92; -.
DR   HGNC; HGNC:49272; C2orf92.
DR   HPA; ENSG00000228486; Tissue enhanced (testis).
DR   neXtProt; NX_A0A1B0GVN3; -.
DR   OpenTargets; ENSG00000228486; -.
DR   VEuPathDB; HostDB:ENSG00000228486; -.
DR   GeneTree; ENSGT00850000133613; -.
DR   OMA; IQDEILM; -.
DR   Pharos; A0A1B0GVN3; Tdark.
DR   PRO; PR:A0A1B0GVN3; -.
DR   Proteomes; UP000005640; Chromosome 2.
DR   RNAct; A0A1B0GVN3; protein.
DR   Bgee; ENSG00000228486; Expressed in right uterine tube and 100 other tissues.
DR   ExpressionAtlas; A0A1B0GVN3; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome; Signal; Transmembrane; Transmembrane helix.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..265
FT                   /note="Uncharacterized protein C2orf92"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_5008408670"
FT   TRANSMEM        192..212
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   265 AA;  30198 MW;  9505459B92BE4E7A CRC64;
     MSRAMALFFV LCWIQDEIVL QVFSKVPYDP SFDETRTAVR SITKRDTQKS YSQQKSLNNA
     AFASGSNERE EHLAKIFDEI LLQVFPKFPY DPSFNEATAV RSITKTDMRK GTSIAWNSPK
     PEYFLGSVDK IPDKDHLSEE KNFKESCLFD RDLREQLTTI DKETLQGAAK PDAHFRTMPC
     GQLLHFLQRN TIIAAVSGVA ILMAIVLLLL GLASYIRKKQ PSSPLANTTY NIFIMDGKTW
     WHNSEEKNFT KLAKKQKQLK SSSCV