YDDA_ECOLI
ID YDDA_ECOLI Reviewed; 561 AA.
AC P31826; P76133; P76876;
DT 01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 2.
DT 03-AUG-2022, entry version 159.
DE RecName: Full=Inner membrane ABC transporter ATP-binding protein YddA;
DE AltName: Full=CDS102;
GN Name=yddA; OrderedLocusNames=b1496, JW5242;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA Wada C., Yamamoto Y., Horiuchi T.;
RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 28.0-40.1 min region on the linkage map.";
RL DNA Res. 3:363-377(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 306-561.
RC STRAIN=K12;
RX PubMed=9116051; DOI=10.1016/s0300-9084(97)84334-9;
RA Turlin E., Gasser F., Biville F.;
RT "Sequence and functional analysis of an Escherichia coli DNA fragment able
RT to complement pqqE and pqqF mutants from Methylobacterium organophilum.";
RL Biochimie 78:823-831(1996).
RN [5]
RP TOPOLOGY [LARGE SCALE ANALYSIS].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=15919996; DOI=10.1126/science.1109730;
RA Daley D.O., Rapp M., Granseth E., Melen K., Drew D., von Heijne G.;
RT "Global topology analysis of the Escherichia coli inner membrane
RT proteome.";
RL Science 308:1321-1323(2005).
CC -!- SUBCELLULAR LOCATION: Cell inner membrane; Multi-pass membrane protein.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA50732.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; U00096; AAC74569.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA15167.2; -; Genomic_DNA.
DR EMBL; X71917; CAA50732.1; ALT_INIT; Genomic_DNA.
DR PIR; C64903; C64903.
DR RefSeq; NP_416013.1; NC_000913.3.
DR RefSeq; WP_000628576.1; NZ_SSZK01000001.1.
DR AlphaFoldDB; P31826; -.
DR SMR; P31826; -.
DR BioGRID; 4260785; 211.
DR STRING; 511145.b1496; -.
DR TCDB; 3.A.1.203.11; the atp-binding cassette (abc) superfamily.
DR PaxDb; P31826; -.
DR PRIDE; P31826; -.
DR EnsemblBacteria; AAC74569; AAC74569; b1496.
DR EnsemblBacteria; BAA15167; BAA15167; BAA15167.
DR GeneID; 945945; -.
DR KEGG; ecj:JW5242; -.
DR KEGG; eco:b1496; -.
DR PATRIC; fig|1411691.4.peg.770; -.
DR EchoBASE; EB1693; -.
DR eggNOG; COG4178; Bacteria.
DR HOGENOM; CLU_007587_6_1_6; -.
DR InParanoid; P31826; -.
DR OMA; FRYGLVH; -.
DR PhylomeDB; P31826; -.
DR BioCyc; EcoCyc:YDDA-MON; -.
DR PRO; PR:P31826; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; ISM:EcoCyc.
DR GO; GO:0005887; C:integral component of plasma membrane; IBA:GO_Central.
DR GO; GO:0005886; C:plasma membrane; IDA:EcoCyc.
DR GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; ISM:EcoCyc.
DR GO; GO:0042626; F:ATPase-coupled transmembrane transporter activity; IBA:GO_Central.
DR Gene3D; 1.20.1560.10; -; 1.
DR Gene3D; 3.40.50.300; -; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011527; ABC1_TM_dom.
DR InterPro; IPR036640; ABC1_TM_sf.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR Pfam; PF06472; ABC_membrane_2; 1.
DR Pfam; PF00005; ABC_tran; 1.
DR SMART; SM00382; AAA; 1.
DR SUPFAM; SSF52540; SSF52540; 1.
DR SUPFAM; SSF90123; SSF90123; 1.
DR PROSITE; PS50929; ABC_TM1F; 1.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 1: Evidence at protein level;
KW ATP-binding; Cell inner membrane; Cell membrane; Membrane;
KW Nucleotide-binding; Reference proteome; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..561
FT /note="Inner membrane ABC transporter ATP-binding protein
FT YddA"
FT /id="PRO_0000093163"
FT TOPO_DOM 1..3
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 4..24
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 25..31
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 32..52
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 53..70
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 92..151
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 152..172
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 173..187
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 188..208
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 209..290
FT /note="Periplasmic"
FT /evidence="ECO:0000255"
FT TRANSMEM 291..311
FT /note="Helical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT TOPO_DOM 312..561
FT /note="Cytoplasmic"
FT /evidence="ECO:0000255"
FT DOMAIN 35..337
FT /note="ABC transmembrane type-1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00441"
FT DOMAIN 367..561
FT /note="ABC transporter"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
FT BINDING 400..407
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00434"
SQ SEQUENCE 561 AA; 64985 MW; 92E47426294413F5 CRC64;
MITIPITLRM LIAKYLCLLK PFWLRKNNKT SVLLIIIILA MILGVVKIQV WLNDWNNDFF
NALSQKETDK LWQLVLWFPA LLGIFVLISV NKTWLIKLLT IRWREWLTDY YLNRWFADKN
YYFTQIYGEH KNTDNPDQRI AEDILLLISK TLSLSFGFIQ SLSMLITFTV ILWESAGTLS
FTVGGTEWNI QGYMVYTVVL IVIGGTLFTH KVGKRIRPLN VEKQRSEATF RTNLVQHNKQ
AELIALSNAE SLQRQELSDN FHTIKENWHR LMNRQRWLDY WQNIYSRSLS VLPYFLLLPQ
FISGQINLGG LMKSRQAFML VSNNLSWFIY KYDELAELAA VIDRLYEFHQ LTEQRPTNKP
KNCQHAVQVA DASIRTPDNK IILENLNFHV SPGKWLLLKG YSGAGKTTLL KTLSHCWPWF
KGDISSPADS WYVSQTPLIK TGLLKEIICK ALPLPVDDKS LSEVLHQVGL GKLAARIHDH
DRWGDILSSG EKQRIALARL ILRRPKWIFL DETTSHLEEQ EAIRLLRLVR EKLPTSGVIM
VTHQPGVWNL ADDICDISAV L
