YDDE_ECOLI
ID YDDE_ECOLI Reviewed; 297 AA.
AC P37757; P77430;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1997, sequence version 2.
DT 03-AUG-2022, entry version 139.
DE RecName: Full=Uncharacterized isomerase YddE;
DE EC=5.1.-.-;
DE AltName: Full=ORFB;
GN Name=yddE; OrderedLocusNames=b1464, JW1459;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA Wada C., Yamamoto Y., Horiuchi T.;
RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 28.0-40.1 min region on the linkage map.";
RL DNA Res. 3:363-377(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-34.
RX PubMed=2233673; DOI=10.1007/bf00283030;
RA Blasco F., Iobbi C., Ratouchniak J., Bonnefoy V., Chippaux M.;
RT "Nitrate reductases of Escherichia coli: sequence of the second nitrate
RT reductase and comparison with that encoded by the narGHJI operon.";
RL Mol. Gen. Genet. 222:104-111(1990).
RN [5]
RP X-RAY CRYSTALLOGRAPHY (2.05 ANGSTROMS), AND SUBUNIT.
RX PubMed=15103639; DOI=10.1002/prot.20025;
RA Grassick A., Sulzenbacher G., Roig-Zamboni V., Campanacci V., Cambillau C.,
RA Bourne Y.;
RT "Crystal structure of E. coli yddE protein reveals a striking homology with
RT diaminopimelate epimerase.";
RL Proteins 55:764-767(2004).
CC -!- SUBUNIT: Homodimer and homotetramer. {ECO:0000269|PubMed:15103639}.
CC -!- SIMILARITY: Belongs to the PhzF family. {ECO:0000305}.
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DR EMBL; U00096; AAC74546.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA15101.1; -; Genomic_DNA.
DR EMBL; X17110; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; C64899; C64899.
DR RefSeq; NP_415981.1; NC_000913.3.
DR RefSeq; WP_000804385.1; NZ_LN832404.1.
DR PDB; 1QY9; X-ray; 2.05 A; A/B/C/D=1-297.
DR PDB; 1QYA; X-ray; 2.00 A; A/B=2-297.
DR PDB; 1SDJ; X-ray; 2.30 A; A=1-297.
DR PDBsum; 1QY9; -.
DR PDBsum; 1QYA; -.
DR PDBsum; 1SDJ; -.
DR AlphaFoldDB; P37757; -.
DR SMR; P37757; -.
DR BioGRID; 4262893; 18.
DR IntAct; P37757; 5.
DR STRING; 511145.b1464; -.
DR jPOST; P37757; -.
DR PaxDb; P37757; -.
DR PRIDE; P37757; -.
DR EnsemblBacteria; AAC74546; AAC74546; b1464.
DR EnsemblBacteria; BAA15101; BAA15101; BAA15101.
DR GeneID; 944782; -.
DR KEGG; ecj:JW1459; -.
DR KEGG; eco:b1464; -.
DR PATRIC; fig|1411691.4.peg.804; -.
DR EchoBASE; EB1772; -.
DR eggNOG; COG0384; Bacteria.
DR HOGENOM; CLU_048756_0_2_6; -.
DR InParanoid; P37757; -.
DR OMA; CHAWLQA; -.
DR PhylomeDB; P37757; -.
DR BioCyc; EcoCyc:EG11825-MON; -.
DR EvolutionaryTrace; P37757; -.
DR PRO; PR:P37757; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0016853; F:isomerase activity; IBA:GO_Central.
DR GO; GO:0009058; P:biosynthetic process; IEA:InterPro.
DR InterPro; IPR003719; Phenazine_PhzF.
DR PANTHER; PTHR13774; PTHR13774; 1.
DR Pfam; PF02567; PhzC-PhzF; 1.
DR PIRSF; PIRSF016184; PhzC_PhzF; 1.
DR TIGRFAMs; TIGR00654; PhzF_family; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Isomerase; Reference proteome.
FT CHAIN 1..297
FT /note="Uncharacterized isomerase YddE"
FT /id="PRO_0000162388"
FT ACT_SITE 46
FT /evidence="ECO:0000250"
FT STRAND 4..10
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 18..25
FT /evidence="ECO:0007829|PDB:1QYA"
FT HELIX 32..42
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 47..51
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 54..63
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 65..69
FT /evidence="ECO:0007829|PDB:1QYA"
FT HELIX 75..87
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 91..97
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 103..110
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 113..119
FT /evidence="ECO:0007829|PDB:1QYA"
FT HELIX 132..140
FT /evidence="ECO:0007829|PDB:1QYA"
FT HELIX 145..147
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 154..161
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 163..168
FT /evidence="ECO:0007829|PDB:1QYA"
FT HELIX 174..176
FT /evidence="ECO:0007829|PDB:1QYA"
FT HELIX 181..191
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 196..201
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 205..210
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 212..214
FT /evidence="ECO:0007829|PDB:1QYA"
FT HELIX 215..217
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 219..224
FT /evidence="ECO:0007829|PDB:1QYA"
FT HELIX 226..238
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 246..255
FT /evidence="ECO:0007829|PDB:1QYA"
FT HELIX 257..259
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 263..272
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 275..283
FT /evidence="ECO:0007829|PDB:1QYA"
FT STRAND 285..292
FT /evidence="ECO:0007829|PDB:1QYA"
SQ SEQUENCE 297 AA; 32319 MW; FB7B2EE8ABDC266E CRC64;
MKPQVYHVDA FTSQPFRGNS AGVVFPADNL SEAQMQLIAR ELGHSETAFL LHSDDSDVRI
RYFTPTVEVP ICGHATVAAH YVRAKVLGLG NCTIWQTSLA GKHRVTIEKH NDDYRISLEQ
GTPGFEPPLE GETRAAIINA LHLTEDDILP GLPIQVATTG HSKVMIPLKP EVDIDALSPD
LNALTAISKK IGCNGFFPFQ IRPGKNETDG RMFSPAIGIV EDPVTGNANG PMGAWLVHHN
VLPHDGNVLR VKGHQGRALG RDGMIEVTVT IRDNQPEKVT ISGTAVILFH AEWAIEL
