YDEO_ECOLI
ID YDEO_ECOLI Reviewed; 253 AA.
AC P76135; P76877;
DT 15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 145.
DE RecName: Full=HTH-type transcriptional regulator YdeO;
GN Name=ydeO; OrderedLocusNames=b1499, JW1494;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA Wada C., Yamamoto Y., Horiuchi T.;
RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 28.0-40.1 min region on the linkage map.";
RL DNA Res. 3:363-377(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [4]
RP INDUCTION.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=12399493; DOI=10.1128/jb.184.22.6225-6234.2002;
RA Masuda N., Church G.M.;
RT "Escherichia coli gene expression responsive to levels of the response
RT regulator EvgA.";
RL J. Bacteriol. 184:6225-6234(2002).
RN [5]
RP FUNCTION.
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=12694615; DOI=10.1046/j.1365-2958.2003.03477.x;
RA Masuda N., Church G.M.;
RT "Regulatory network of acid resistance genes in Escherichia coli.";
RL Mol. Microbiol. 48:699-712(2003).
CC -!- FUNCTION: Induces the expression of gadE and mdtEF. Could also regulate
CC the expression of other genes involved in acid resistance.
CC {ECO:0000269|PubMed:12694615}.
CC -!- INDUCTION: Induced by EvgA. {ECO:0000269|PubMed:12399493}.
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DR EMBL; U00096; AAC74572.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA15173.2; -; Genomic_DNA.
DR PIR; F64903; F64903.
DR RefSeq; NP_416016.1; NC_000913.3.
DR RefSeq; WP_000060495.1; NZ_LN832404.1.
DR AlphaFoldDB; P76135; -.
DR SMR; P76135; -.
DR BioGRID; 4260212; 7.
DR BioGRID; 850287; 1.
DR IntAct; P76135; 1.
DR STRING; 511145.b1499; -.
DR PaxDb; P76135; -.
DR PRIDE; P76135; -.
DR EnsemblBacteria; AAC74572; AAC74572; b1499.
DR EnsemblBacteria; BAA15173; BAA15173; BAA15173.
DR GeneID; 945922; -.
DR KEGG; ecj:JW1494; -.
DR KEGG; eco:b1499; -.
DR PATRIC; fig|1411691.4.peg.767; -.
DR EchoBASE; EB3558; -.
DR eggNOG; COG2207; Bacteria.
DR HOGENOM; CLU_000445_81_4_6; -.
DR InParanoid; P76135; -.
DR OMA; HMGMNTG; -.
DR PhylomeDB; P76135; -.
DR BioCyc; EcoCyc:G6789-MON; -.
DR PRO; PR:P76135; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IDA:EcoCyc.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:EcoCyc.
DR GO; GO:0006351; P:transcription, DNA-templated; IDA:EcoCyc.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR018060; HTH_AraC.
DR InterPro; IPR018062; HTH_AraC-typ_CS.
DR InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR Pfam; PF12833; HTH_18; 1.
DR PRINTS; PR00032; HTHARAC.
DR SMART; SM00342; HTH_ARAC; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE 2: Evidence at transcript level;
KW Activator; DNA-binding; Reference proteome; Transcription;
KW Transcription regulation.
FT CHAIN 1..253
FT /note="HTH-type transcriptional regulator YdeO"
FT /id="PRO_0000194606"
FT DOMAIN 137..233
FT /note="HTH araC/xylS-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT DNA_BIND 154..175
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT DNA_BIND 200..223
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
SQ SEQUENCE 253 AA; 28725 MW; 6898BBAA54DAA997 CRC64;
MSLVCSVIFI HHAFNANILD KDYAFSDGEI LMVDNAVRTH FEPYERHFKE IGFTENTIKK
YLQCTNIQTV TVPVPAKFLR ASNVPTGLLN EMIAYLNSEE RNHHNFSELL LFSCLSIFAA
CKGFITLLTN GVLSVSGKVR NIVNMKPAHP WKLKDICDCL YISESLLKKK LKQEQTTFSQ
ILLDARMQHA KNLIRVEGSV NKIAEQCGYA STSYFIYAFR KHFGNSPKRV SKEYRCQSHT
GMNTGNTMNA LAI
