ID   YDEO_SHIFL              Reviewed;         253 AA.
AC   Q83RF4; Q7C1L6;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 114.
DE   RecName: Full=HTH-type transcriptional regulator YdeO;
GN   Name=ydeO; OrderedLocusNames=SF1537, S1654;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: Induces the expression of gadE. Could also regulate the
CC       expression of other genes involved in acid resistance (By similarity).
CC       {ECO:0000250}.
CC   -!- INDUCTION: Induced by EvgA. {ECO:0000250}.
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DR   EMBL; AE005674; AAN43126.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP17017.1; -; Genomic_DNA.
DR   RefSeq; NP_707419.1; NC_004337.2.
DR   RefSeq; WP_000060475.1; NZ_WPGV01000167.1.
DR   AlphaFoldDB; Q83RF4; -.
DR   SMR; Q83RF4; -.
DR   STRING; 198214.SF1537; -.
DR   DNASU; 1077977; -.
DR   EnsemblBacteria; AAN43126; AAN43126; SF1537.
DR   EnsemblBacteria; AAP17017; AAP17017; S1654.
DR   GeneID; 1024745; -.
DR   GeneID; 58391815; -.
DR   KEGG; sfl:SF1537; -.
DR   KEGG; sfx:S1654; -.
DR   PATRIC; fig|198214.7.peg.1814; -.
DR   HOGENOM; CLU_000445_81_4_6; -.
DR   OMA; HMGMNTG; -.
DR   OrthoDB; 1268974at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR018060; HTH_AraC.
DR   InterPro; IPR018062; HTH_AraC-typ_CS.
DR   InterPro; IPR020449; Tscrpt_reg_HTH_AraC-type.
DR   Pfam; PF12833; HTH_18; 1.
DR   PRINTS; PR00032; HTHARAC.
DR   SMART; SM00342; HTH_ARAC; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00041; HTH_ARAC_FAMILY_1; 1.
DR   PROSITE; PS01124; HTH_ARAC_FAMILY_2; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..253
FT                   /note="HTH-type transcriptional regulator YdeO"
FT                   /id="PRO_0000194609"
FT   DOMAIN          137..233
FT                   /note="HTH araC/xylS-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        154..175
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
FT   DNA_BIND        200..223
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00593"
SQ   SEQUENCE   253 AA;  28796 MW;  B223D9DDA763D8DB CRC64;
     MSLVCSVIFI HHAFNANILD KDYAFSDGEI LMVDNAVRTH FEPYERHFKE IGFNENTIKK
     YLQCTNIQTV TVPVPAKFLR ASNVPTGLLN EMIAYLNSEE RNHHNFSELL LFSCLSIFAA
     CKGFITLLTN GVLSVSGKVR NIVNMKLAHP WKLKDICDCL YISESLLKKK LKQEQTTFSQ
     ILLDARMQHA KNLIRVEGSV NKIAEQCGYA STSYFIYAFR KHFGNSPKRV SKEYRCQRHT
     GMNTGNTMSA LAI