ID   YDFJ_BACSU              Reviewed;         724 AA.
AC   P96687; Q797G4;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1997, sequence version 1.
DT   03-AUG-2022, entry version 108.
DE   RecName: Full=Membrane protein YdfJ;
GN   Name=ydfJ; OrderedLocusNames=BSU05430;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RA   Kasahara Y., Nakai S., Lee S., Sadaie Y., Ogasawara N.;
RT   "A 148 kbp sequence of the region between 35 and 47 degree of the Bacillus
RT   subtilis genome.";
RL   Submitted (MAR-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   TRANSCRIPTIONAL REGULATION.
RC   STRAIN=168;
RX   PubMed=15941986; DOI=10.1099/mic.0.27619-0;
RA   Serizawa M., Sekiguchi J.;
RT   "The Bacillus subtilis YdfHI two-component system regulates the
RT   transcription of ydfJ, a member of the RND superfamily.";
RL   Microbiology 151:1769-1778(2005).
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- INDUCTION: Regulated by the two-component regulatory system YdfH/YdfI.
CC       {ECO:0000269|PubMed:15941986}.
CC   -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC       (TC 2.A.6) family. MmpL subfamily. {ECO:0000305}.
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DR   EMBL; AB001488; BAA19377.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12350.1; -; Genomic_DNA.
DR   PIR; H69780; H69780.
DR   RefSeq; NP_388424.1; NC_000964.3.
DR   RefSeq; WP_003243548.1; NZ_JNCM01000031.1.
DR   AlphaFoldDB; P96687; -.
DR   SMR; P96687; -.
DR   STRING; 224308.BSU05430; -.
DR   PaxDb; P96687; -.
DR   PRIDE; P96687; -.
DR   EnsemblBacteria; CAB12350; CAB12350; BSU_05430.
DR   GeneID; 939901; -.
DR   KEGG; bsu:BSU05430; -.
DR   PATRIC; fig|224308.179.peg.582; -.
DR   eggNOG; COG2409; Bacteria.
DR   InParanoid; P96687; -.
DR   OMA; SLMFAHI; -.
DR   PhylomeDB; P96687; -.
DR   BioCyc; BSUB:BSU05430-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR004869; MMPL_dom.
DR   InterPro; IPR000731; SSD.
DR   Pfam; PF03176; MMPL; 2.
DR   PROSITE; PS50156; SSD; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..724
FT                   /note="Membrane protein YdfJ"
FT                   /id="PRO_0000103585"
FT   TRANSMEM        17..37
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        179..199
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        200..220
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        231..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        277..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        309..329
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        360..380
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        512..532
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        539..559
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        575..595
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        627..647
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        655..675
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   724 AA;  77033 MW;  13355D5CA970C59B CRC64;
     MSKMLYTLGG WVARNRIKAI CAWIVVLVAA IGLAVTLKPS FSEDMSIPDT PSEKAMDVIQ
     KEFPHGPDKG SIRVIFGAGD GEKLTGKPAK KAIEDTFKEI SKDDSVDSIA SPFVTGTIAK
     DGTVAYADIQ YKSSADDIKD YSIKHLKDSL KMADDEGLQT ELSGDVPGAE MEIGGVSEIV
     GIILAFVVLA ITFGSLLIAG LPILTALIGL GVSIGLVLIG TQVFDIASVS LSLAGMIGLA
     VGIDYALFIF TKHRQFLGEG IQKNESIARA VGTAGSAVVF AGLTVIVALC GLTVVNIPFM
     SAMGLTAGLS VLMAVLASIT LVPAVLSIAG KRMIPKSNKK IEKQSTETNV WGRFVTKNPI
     MLSVCSILIL IVISIPSMHL ELGLPDAGMK AKDNPDRRAY DLLAEGFGEG FNGQLTIVAD
     ATNATENKAE AFADAVKEIK GLDHVASVTP AMPNKEGNFA IITVVPETGP NDVTTKDLVH
     DVRSLSDKNG VDLLVTGSTA VNIDISDRLN DAIPVFAVLI VGFAFVLLTI VFRSLLVPLV
     AVAGFMLTMT ATLGICVFVL QDGNLIDFFK IPEKGPILAF LPILSIGILF GLAMDYQVFL
     VSRMREEYVK TNNPVQAIQA GLKHSGPVVT AAGLIMIFVF AGFIFAGEAS IKANGLALSF
     GVLFDAFIVR MTLIPSVMKL MGNAAWYLPK WLDKIIPNVD IEGHQLTKEI QPEIDHEQKK
     QISV