YDGD_ECOLI
ID YDGD_ECOLI Reviewed; 273 AA.
AC P76176; Q2MB76;
DT 01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1997, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Uncharacterized serine protease YdgD;
DE EC=3.4.21.-;
DE Flags: Precursor;
GN Name=ydgD; OrderedLocusNames=b1598, JW1590;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
CC -!- SIMILARITY: Belongs to the peptidase S1B family. {ECO:0000305}.
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DR EMBL; U00096; AAC74670.1; -; Genomic_DNA.
DR EMBL; AP009048; BAE76480.1; -; Genomic_DNA.
DR PIR; H64915; H64915.
DR RefSeq; NP_416115.1; NC_000913.3.
DR RefSeq; WP_001260865.1; NZ_SSZK01000001.1.
DR AlphaFoldDB; P76176; -.
DR BioGRID; 4259123; 34.
DR DIP; DIP-11712N; -.
DR STRING; 511145.b1598; -.
DR MEROPS; S01.260; -.
DR jPOST; P76176; -.
DR PaxDb; P76176; -.
DR PRIDE; P76176; -.
DR EnsemblBacteria; AAC74670; AAC74670; b1598.
DR EnsemblBacteria; BAE76480; BAE76480; BAE76480.
DR GeneID; 946436; -.
DR KEGG; ecj:JW1590; -.
DR KEGG; eco:b1598; -.
DR PATRIC; fig|1411691.4.peg.664; -.
DR EchoBASE; EB3684; -.
DR eggNOG; COG3591; Bacteria.
DR HOGENOM; CLU_078170_0_0_6; -.
DR InParanoid; P76176; -.
DR OMA; HQDCLIT; -.
DR PhylomeDB; P76176; -.
DR BioCyc; EcoCyc:G6856-MON; -.
DR PRO; PR:P76176; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR Gene3D; 2.40.10.10; -; 2.
DR InterPro; IPR009003; Peptidase_S1_PA.
DR InterPro; IPR043504; Peptidase_S1_PA_chymotrypsin.
DR InterPro; IPR008256; Peptidase_S1B.
DR InterPro; IPR001254; Trypsin_dom.
DR InterPro; IPR018114; TRYPSIN_HIS.
DR InterPro; IPR033116; TRYPSIN_SER.
DR Pfam; PF00089; Trypsin; 1.
DR PRINTS; PR00839; V8PROTEASE.
DR SUPFAM; SSF50494; SSF50494; 1.
DR PROSITE; PS00134; TRYPSIN_HIS; 1.
DR PROSITE; PS00135; TRYPSIN_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase; Protease; Reference proteome; Serine protease; Signal.
FT SIGNAL 1..21
FT /evidence="ECO:0000255"
FT CHAIN 22..273
FT /note="Uncharacterized serine protease YdgD"
FT /id="PRO_0000026904"
FT ACT_SITE 84
FT /note="Charge relay system"
FT /evidence="ECO:0000250"
FT ACT_SITE 223
FT /note="Charge relay system"
FT /evidence="ECO:0000250"
SQ SEQUENCE 273 AA; 29277 MW; C8FCD018A59DBC62 CRC64;
MRTTIAVVLG AISLTSAFVF ADKPDVARSA NDEVSTLFFG HDDRVPVNDT TQSPWDAVGQ
LETASGNLCT ATLIAPNLAL TAGHCLLTPP KGKADKAVAL RFVSNKGLWR YEIHDIEGRV
DPTLGKRLKA DGDGWIVPPA AAPWDFGLIV LRNPPSGITP LPLFEGDKAA LTAALKAAGR
KVTQAGYPED HLDTLYSHQN CEVTGWAQTS VMSHQCDTLP GDSGSPLMLH TDDGWQLIGV
QSSAPAAKDR WRADNRAISV TGFRDKLDQL SQK
