ID   YDGT_SALCH              Reviewed;          71 AA.
AC   Q57PH6;
DT   02-OCT-2007, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 2.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Transcription modulator YdgT;
DE   AltName: Full=H-NS/StpA-binding protein 2;
DE   AltName: Full=OriC-binding nucleoid-associated protein;
GN   Name=ydgT; Synonyms=cnu; OrderedLocusNames=SCH_1479;
OS   Salmonella choleraesuis (strain SC-B67).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=321314;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC-B67;
RX   PubMed=15781495; DOI=10.1093/nar/gki297;
RA   Chiu C.-H., Tang P., Chu C., Hu S., Bao Q., Yu J., Chou Y.-Y., Wang H.-S.,
RA   Lee Y.-S.;
RT   "The genome sequence of Salmonella enterica serovar Choleraesuis, a highly
RT   invasive and resistant zoonotic pathogen.";
RL   Nucleic Acids Res. 33:1690-1698(2005).
CC   -!- FUNCTION: Binds to H-NS and modified the range of genes it silences; H-
CC       NS alonge silences core gene while the H-NS-Hha complex (and presumably
CC       also H-NS-YdgT) silences genes acquired by horizontal gene transfer.
CC       Plays a role silencing virulence factors in the absence of factors that
CC       induce pathogenicity (By similarity). The complex formed with H-NS
CC       binds to the specific 26-bp cnb site in the origin of replication oriC
CC       (By similarity). {ECO:0000250|UniProtKB:A0A0H3NGF1,
CC       ECO:0000250|UniProtKB:P64467}.
CC   -!- SUBUNIT: Forms complexes with both H-NS and StpA.
CC       {ECO:0000250|UniProtKB:Q7CQK5}.
CC   -!- SIMILARITY: Belongs to the Hha/YmoA/Cnu family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAX65385.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AE017220; AAX65385.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_000217946.1; NC_006905.1.
DR   AlphaFoldDB; Q57PH6; -.
DR   SMR; Q57PH6; -.
DR   EnsemblBacteria; AAX65385; AAX65385; SCH_1479.
DR   GeneID; 66755902; -.
DR   KEGG; sec:SCH_1479; -.
DR   HOGENOM; CLU_190629_0_0_6; -.
DR   Proteomes; UP000000538; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.1280.40; -; 1.
DR   InterPro; IPR007985; Hemolysn_expr_modulating_HHA.
DR   InterPro; IPR036666; HHA_sf.
DR   Pfam; PF05321; HHA; 1.
DR   SUPFAM; SSF68989; SSF68989; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Transcription; Transcription regulation.
FT   CHAIN           1..71
FT                   /note="Transcription modulator YdgT"
FT                   /id="PRO_0000305051"
FT   SITE            44
FT                   /note="Interacts with H-NS"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   71 AA;  8381 MW;  37948CE3814FADA8 CRC64;
     MTVQDYLLKF RKISSLESLE KLFDHLNYTL TDDMDIVNMY RAADHRRAEL VSGGRLFDVG
     QVPQSVWRYV Q