YDHB_ECOLI
ID YDHB_ECOLI Reviewed; 310 AA.
AC P0ACR2; P37598; P77677;
DT 22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT 22-NOV-2005, sequence version 1.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Uncharacterized HTH-type transcriptional regulator YdhB;
GN Name=ydhB; OrderedLocusNames=b1659, JW1651;
OS Escherichia coli (strain K12).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=83333;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=K12 / RR28;
RX PubMed=9022701; DOI=10.1111/j.1432-1033.1996.0712r.x;
RA Eberhardt S.M.R., Richter G., Gimbel W., Werner T., Bacher A.;
RT "Cloning, sequencing, mapping and hyperexpression of the ribC gene coding
RT for riboflavin synthase of Escherichia coli.";
RL Eur. J. Biochem. 242:712-719(1996).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=9097039; DOI=10.1093/dnares/3.6.363;
RA Aiba H., Baba T., Fujita K., Hayashi K., Inada T., Isono K., Itoh T.,
RA Kasai H., Kashimoto K., Kimura S., Kitakawa M., Kitagawa M., Makino K.,
RA Miki T., Mizobuchi K., Mori H., Mori T., Motomura K., Nakade S.,
RA Nakamura Y., Nashimoto H., Nishio Y., Oshima T., Saito N., Sampei G.,
RA Seki Y., Sivasundaram S., Tagami H., Takeda J., Takemoto K., Takeuchi Y.,
RA Wada C., Yamamoto Y., Horiuchi T.;
RT "A 570-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT the 28.0-40.1 min region on the linkage map.";
RL DNA Res. 3:363-377(1996).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / MG1655 / ATCC 47076;
RX PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA Shao Y.;
RT "The complete genome sequence of Escherichia coli K-12.";
RL Science 277:1453-1462(1997).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND SEQUENCE REVISION TO
RP 253.
RC STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX PubMed=16738553; DOI=10.1038/msb4100049;
RA Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT and W3110.";
RL Mol. Syst. Biol. 2:E1-E5(2006).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 106-310.
RC STRAIN=K12;
RX PubMed=2404765; DOI=10.1111/j.1432-1033.1990.tb15314.x;
RA Meng L.M., Kilstrup M., Nygaard P.;
RT "Autoregulation of PurR repressor synthesis and involvement of purR in the
RT regulation of purB, purC, purL, purMN and guaBA expression in Escherichia
RT coli.";
RL Eur. J. Biochem. 187:373-379(1990).
RN [6]
RP IDENTIFICATION.
RA Rudd K.E.;
RL Unpublished observations (FEB-1994).
CC -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC {ECO:0000305}.
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DR EMBL; X69109; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; U00096; AAC74731.1; -; Genomic_DNA.
DR EMBL; AP009048; BAA15425.2; -; Genomic_DNA.
DR EMBL; X51368; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR PIR; E64923; E64923.
DR RefSeq; NP_416176.1; NC_000913.3.
DR RefSeq; WP_000269501.1; NZ_SSZK01000001.1.
DR AlphaFoldDB; P0ACR2; -.
DR SMR; P0ACR2; -.
DR BioGRID; 4262908; 22.
DR IntAct; P0ACR2; 5.
DR STRING; 511145.b1659; -.
DR PaxDb; P0ACR2; -.
DR PRIDE; P0ACR2; -.
DR EnsemblBacteria; AAC74731; AAC74731; b1659.
DR EnsemblBacteria; BAA15425; BAA15425; BAA15425.
DR GeneID; 66674448; -.
DR GeneID; 945208; -.
DR KEGG; ecj:JW1651; -.
DR KEGG; eco:b1659; -.
DR PATRIC; fig|1411691.4.peg.598; -.
DR EchoBASE; EB2061; -.
DR eggNOG; COG0583; Bacteria.
DR HOGENOM; CLU_039613_35_1_6; -.
DR InParanoid; P0ACR2; -.
DR OMA; PKRTTWL; -.
DR PhylomeDB; P0ACR2; -.
DR BioCyc; EcoCyc:EG12140-MON; -.
DR PRO; PR:P0ACR2; -.
DR Proteomes; UP000000318; Chromosome.
DR Proteomes; UP000000625; Chromosome.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR Gene3D; 1.10.10.10; -; 1.
DR InterPro; IPR005119; LysR_subst-bd.
DR InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR Pfam; PF00126; HTH_1; 1.
DR Pfam; PF03466; LysR_substrate; 1.
DR SUPFAM; SSF46785; SSF46785; 1.
DR PROSITE; PS50931; HTH_LYSR; 1.
PE 3: Inferred from homology;
KW DNA-binding; Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..310
FT /note="Uncharacterized HTH-type transcriptional regulator
FT YdhB"
FT /id="PRO_0000105784"
FT DOMAIN 1..59
FT /note="HTH lysR-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT DNA_BIND 19..38
FT /note="H-T-H motif"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00253"
FT CONFLICT 253
FT /note="K -> E (in Ref. 2)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 310 AA; 35250 MW; BBC7A2F2B2AC351A CRC64;
MWSEYSLEVV DAVARNGSFS AAAQELHRVP SAVSYTVRQL EEWLAVPLFE RRHRDVELTA
AGAWFLKEGR SVVKKMQITR QQCQQIANGW RGQLAIAVDN IVRPERTRQM IVDFYRHFDD
VELLVFQEVF NGVWDALSDG RVELAIGATR AIPVGGRYAF RDMGMLSWSC VVASHHPLAL
MDGPFSDDTL RNWPSLVRED TSRTLPKRIT WLLDNQKRVV VPDWESSATC ISAGLCIGMV
PTHFAKPWLN EGKWVALELE NPFPDSACCL TWQQNDMSPA LTWLLEYLGD SETLNKEWLR
EPEETPATGD
